HIV-1 Transmembrane Glycoprotein (HIV-1 gp41) Protein

Catalog No. ABIN934416

Product Details

Target: HIV-1 Transmembrane Glycoprotein (HIV-1 gp41)

Protein Type: Recombinant

Origin: Human Immunodeficiency Virus (HIV)

Source: Escherichia coli (E. coli)

Application: ELISA, Western Blotting (WB)

Characteristics: Purified recombinant HIV1 gp41 protein
Expression System: E.coli

Purity: > 98 % pure

Application Details

Application Notes: ELISA: 1:500-1:1,000, WB: 1:500-1:1,000

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Reconstitute in sterile distilled water.

Buffer: Supplied lyophilized from PBS buffer, with no preservatives added,

Preservative: Without preservative

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C until reconstitution. Following reconstitution aliquot and freeze at -70 °C for long term storage.

References

Du, Idiart, Mariano, Chen, Jiang, Xu, Ostrow, Wrin, Phung, Binley, Petropoulos, Ballantyne, Whalen: "Effect of trimerization motifs on quaternary structure, antigenicity, and immunogenicity of a noncleavable HIV-1 gp140 envelope glycoprotein." in: Virology, Vol. 395, Issue 1, pp. 33-44, (2009) (PubMed).

Opalka, Pessi, Bianchi, Ciliberto, Schleif, McElhaugh, Danzeisen, Geleziunas, Miller, Eckert, Bramhill, Joyce, Cook, Magilton, Shiver, Emini, Esser: "Analysis of the HIV-1 gp41 specific immune response using a multiplexed antibody detection assay." in: Journal of immunological methods, Vol. 287, Issue 1-2, pp. 49-65, (2004) (PubMed).

Target Details

Target: HIV-1 Transmembrane Glycoprotein (HIV-1 gp41)

Alternative Name: HIV1 gp41

Target Type: Viral Protein

Background: GP41 is a glycoprotein subunit that remains non-covalently-bound to gp120, and provides the second step by which HIV enters the cell. It is originally buried within the viral envelope, but, when gp120 binds to a CD4, gp120 changes its conformation, causing gp41 to become exposed, where it can assist in fusion with the host cell.
Alternative Names: gp41 antigen, HIV 1 gp41, HIV-1 gp41 protein, gp41 antigen, gp41 glycoprotein antigen, Glycoprotein 41 antigen, Envelope surface glycoprotein gp41 antigen, HIV-1 gp41 antigen, Human Immunodeficiency Virus 1 antigen, HIV1 gp41, Surface protein antigen, SU antigen, HIV 1 gp41 protein, HIV-1 gp41, HIV 1 gp41 antigen