IL1RN Protein

Catalog No. ABIN934932

Product Details

Target: IL1RN (Interleukin 1 Receptor Antagonist (IL1RN))

Protein Type: Recombinant

Origin: Human

Source: Escherichia coli (E. coli)

Application: SDS-PAGE (SDS)

Sequence: MRPSGRKSSK MQAFRIWDVN QKTFYLRNNQ LVAGYLQGPN VNLEEKIDVV PIEPHALFLG IHGGKMCLSC VKSGDETRLQ LEAVNITDLS ENRKQDKRFA FIRSDSGPTT SFESAACPGW FLCTAMEADQ PVSLTNMPDE GVMVTKFYFQ EDE

Characteristics: Purified recombinant Human IL1 receptor antagonist protein
Expression System: E.coli
Molecular weight on SDS-PAGE will appear higher.

Purity: > 95 % pure

Application Details

Application Notes: IL1 protein has been used in SDS PAGE and may be suitable for use in other assays to be determined by the end user.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Supplied as a liquid in PBS, pH 7.4.

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: RT/-20 °C

Storage Comment: Store at 4 °C for short term storage (1/2 weeks). Aliquot and store at -20 °C or - 70 °C for long term storage.

Target Details

Target: IL1RN (Interleukin 1 Receptor Antagonist (IL1RN))

Alternative Name: IL1 receptor antagonist (IL1RN Products)

Synonyms: DIRA Protein, ICIL-1RA Protein, IL-1RN Protein, IL-1ra Protein, IL-1ra3 Protein, IL1F3 Protein, IL1RA Protein, IRAP Protein, MVCD4 Protein, IRAP1 Protein, IL1RN Protein, IL-1RA Protein, F630041P17Rik Protein, interleukin 1 receptor antagonist Protein, interleukin 1 receptor antagonist-like Protein, IL1RN Protein, Il1rn Protein, IL1RNL Protein

Background: One of the most potent pro-inflammatory mediators is the early-acting cytokine interleukin-1 (IL-1), whose actions are regulated by the structurally related IL-1 receptor antagonist (IL-1 RA). IL-1 RA is a competitive IL-1 inhibitor and a powerful anti-inflammatory agent. Also, Several autoimmune and inflammatory diseases have been associated with an allelic polymorphism of the IL-1 RA gene. Recombinant human IL-1 RA was expressed in E. coli and purified by using conventional chromatography techniques.
Alternative Names: Anakinra protein, Interleukin-1 receptor antagonist protein, , IL1 inhibitor protein, IL-1, IL 1, IL1F3 protein, IL-1 protein, IL-1ra protein, ICIL-1RA protein, IL 1 protein, IL1, IL1RN protein, ICIL 1RA protein, Interleukin-1 receptor antagonist protein protein, ICIL1RA protein, IRAP protein, IL-1RN protein, IL1 inhibitor protein, IL1RA protein

Molecular Weight: 17.2 kDa (153 AA)

Pathways: NF-kappaB Signaling, Hormone Transport, Cancer Immune Checkpoints