Thymic Stromal Lymphopoietin Protein (TSLP)
Quick Overview for Thymic Stromal Lymphopoietin Protein (TSLP) (ABIN935841)
Target
See all Thymic Stromal Lymphopoietin (TSLP) ProteinsProtein Type
Origin
Source
Purity
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Sequence
- MYDFTNCDFE KIKAAYLSTI SKDLITYMSG TKSTEFNNTV SCSNRPHCLT EIQSLTFNPT AGCASLAKE MFAMKTKAAL AIWCPGYSET QINATQAMKK RRKRKVTTNK CLEQVSQLQG L WRRFNRPL LKQQ
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Characteristics
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Purified recombinant Human TSLP protein
Expression System: E.coli -
Endotoxin Level
- < 0.1 ng per µg (1 EU/µg).
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Thymic Stromal Lymphopoietin (TSLP) (AA 29-159) protein (His-Avi Tag)
TSLP Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Thymic Stromal Lymphopoietin (TSLP) (AA 29-159), (R127A), (R130A) protein (His-Avi Tag,Biotin)TSLP Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Thymic Stromal Lymphopoietin (TSLP) (AA 29-159), (R127A), (R130A) protein (His-Avi Tag)TSLP Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Thymic Stromal Lymphopoietin (TSLP) (AA 29-159) protein (His tag)TSLP Origin: Cynomolgus Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Thymic Stromal Lymphopoietin (TSLP) (Active) protein (His tag)TSLP Origin: Human Host: Human Cells Recombinant >95 % as determined by reducing SDS-PAGE. Active
Thymic Stromal Lymphopoietin (TSLP) (Active) protein (His tag)TSLP Origin: Cynomolgus Host: Escherichia coli (E. coli) Recombinant >95 % as determined by reducing SDS-PAGE. Active
Thymic Stromal Lymphopoietin (TSLP) (AA 29-159) (Active) protein (His tag)TSLP Origin: Cynomolgus Host: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE. Active
Thymic Stromal Lymphopoietin (TSLP) (AA 29-159) (Active) protein (His tag,AVI tag,Biotin)TSLP Origin: Human Host: HEK-293 Cells Recombinant >85 % as determined by SDS-PAGE. Active
Thymic Stromal Lymphopoietin (TSLP) (Active) proteinTSLP Origin: Human Host: Escherichia coli (E. coli) Recombinant >95 % as determined by SDS-PAGE Func Active
Thymic Stromal Lymphopoietin (TSLP) (R127A), (R130A) protein (His tag)TSLP Origin: Human Host: Human Cells Recombinant >95 % as determined by reducing SDS-PAGE.
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Reconstitute in water to a concentration of 0.1 - 1.0 mg/mL.
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Buffer
- Lyophilized from NaC2H3O2, pH 6.0.
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Handling Advice
- Avoid repeated freeze/thaw cycles.
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Storage
- 4 °C/-20 °C
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Storage Comment
- Store at 4 °C until reconstitution. Following reconstitution aliquot and freeze at -20 °C for long term storage.
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- Thymic Stromal Lymphopoietin (TSLP)
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Alternative Name
- TSLP
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Background
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TSLP is a hemopoietic protein that is expressed in the heart, liver and prostate. TSLP overlaps biological activities with IL7 and binds with the heterodimeric receptor complex consisting of the IL7R alpha chain (IL7Ra) and the TSLP-specific chain (TSLPR). Like IL7, TSLP induces phosphorylation of STAT3 and STAT5, but uses kinases other than the JAKs for activation. TSLP prohibited apoptosis and stimulated growth of the human acute myeloid leukemia (AML)-derived cell line MUTZ3. It induces the release of T cell-attracting chemokines TARC and MDC from monocytes and activates CD11c(+) dendritic cells (DCs).
Alternative Names: Thymic Stromal Lymphopoietin protein, TSLP protein -
Molecular Weight
- 15.0 kDa
Target
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