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CD152 Mulg Protein

Origin: Human Host: BHK Cells Recombinant > 95 % pure FACS, ELISA
Catalog No. ABIN935913
  • Target
    CD152 Mulg
    Protein Type
    Recombinant
    Origin
    Human
    Source
    BHK Cells
    Application
    Flow Cytometry (FACS), ELISA
    Characteristics
    Purified recombinant Human CD152 Mulg Fusion protein
    Expression System: BHK cells
    Contaminants: Less than 1 % Bovine Immunoglobulin.
    Purification
    Protein A chromatography
    Purity
    > 95 % pure
    Sterility
    Sterile filtered
  • Application Notes
    FC: 0.5 µg/mL
    Comment

    The CD152 Ig fusion protein has biological activity and binds with high affinity to human or mouse CD80 and CD86. CD152 Ig will block the binding of anti-CD80 and anti-CD86 monoclonal antibodies.

    Restrictions
    For Research Use only
  • Concentration
    0.5 mg/mL
    Buffer
    50 mM Na3PO4 pH 7.5, with 100 mM KCl, and 150 mM NaCl. No preservatives added. Product was sterile filtered under aseptic conditions.
    Contaminants: Less than 1 % Bovine Immunoglobulin.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Open under aseptic sconditions.
    Do not freeze.
    Storage
    4 °C
    Storage Comment
    Store at 4 °C.
  • Target
    CD152 Mulg
    Sub Type
    Fusionprotein
    Background
    Human CD152 is a cell surface glycoprotein expressed at low levels on activated T cells. CD152 is a high affinity receptor for the costimulatory molecules CD80 (B7-1) and CD86 (B7-2) and appears to function as a negative regulator of T cell activation. Therefore, CD152 may be an important player in down regulating T cell mediated immune responses.
    Alternative Names: CD 152 protein, CD152, CD 152, CD-152, CD-152 protein
    Molecular Weight
    110 kDa
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