CD152 Mulg Protein
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- Target
- CD152 Mulg
- Protein Type
- Recombinant
- Origin
- Human
- Source
- BHK Cells
- Application
- Flow Cytometry (FACS), ELISA
- Characteristics
-
Purified recombinant Human CD152 Mulg Fusion protein
Expression System: BHK cells
Contaminants: Less than 1 % Bovine Immunoglobulin. - Purification
- Protein A chromatography
- Purity
- > 95 % pure
- Sterility
- Sterile filtered
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- Application Notes
- FC: 0.5 µg/mL
- Comment
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The CD152 Ig fusion protein has biological activity and binds with high affinity to human or mouse CD80 and CD86. CD152 Ig will block the binding of anti-CD80 and anti-CD86 monoclonal antibodies.
- Restrictions
- For Research Use only
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- Concentration
- 0.5 mg/mL
- Buffer
-
50 mM Na3PO4 pH 7.5, with 100 mM KCl, and 150 mM NaCl. No preservatives added. Product was sterile filtered under aseptic conditions.
Contaminants: Less than 1 % Bovine Immunoglobulin. - Preservative
- Sodium azide
- Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
-
Open under aseptic sconditions.
Do not freeze. - Storage
- 4 °C
- Storage Comment
- Store at 4 °C.
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- Target
- CD152 Mulg
- Sub Type
- Fusionprotein
- Background
-
Human CD152 is a cell surface glycoprotein expressed at low levels on activated T cells. CD152 is a high affinity receptor for the costimulatory molecules CD80 (B7-1) and CD86 (B7-2) and appears to function as a negative regulator of T cell activation. Therefore, CD152 may be an important player in down regulating T cell mediated immune responses.
Alternative Names: CD 152 protein, CD152, CD 152, CD-152, CD-152 protein - Molecular Weight
- 110 kDa
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