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PTP4A1 Products

(Protein Tyrosine Phosphatase Type IVA, Member 1 (PTP4A1))

Categories

The protein encoded by this gene belongs to a small class of prenylated protein tyrosine phosphatases (PTPs), which contains a PTP domain and a characteristic C-terminal prenylation motif. PTPs are cell signaling molecules that play regulatory roles in a variety of cellular processes. This tyrosine phosphatase is a nuclear protein, but may primarily associate with plasma membrane. The surface membrane association of this protein depends on its C-terminal prenylation. Overexpression of this gene in mammalian cells conferred a transformed phenotype, which implicated its role in the tumorigenesis. Studies in rat suggested that this gene may be an immediate-early gene in mitogen-stimulated cells. [provided by RefSeq, Jul 2008].

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Featured PTP4A1 Categories

PTP4A1 Antibodies

High quality antibodies with extensive validation data.

PTP4A1 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended PTP4A1 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse
Application WB, ELISA, IF
Validations
  • (2)
  • (2)
Cat. No. ABIN185274
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, IHC, IF, ICC
Validations
  • (2)
Cat. No. ABIN6264513
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application WB
Validations
  • (2)
Cat. No. ABIN1536716
Quantity 400 μL
Datasheet Datasheet

Recommended PTP4A1 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (2)
Cat. No. ABIN7275477
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7124677
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1316799
Quantity 10 μg
Datasheet Datasheet

Latest Publications for our PTP4A1 products

Min, Kim, Heo, Kim, Kim, Kim, Han, Kim, Yoo: "New p53 target, phosphatase of regenerating liver 1 (PRL-1) downregulates p53." in: Oncogene, Vol. 28, Issue 4, pp. 545-54, (2009) (PubMed).

Achiwa, Lazo: "PRL-1 tyrosine phosphatase regulates c-Src levels, adherence, and invasion in human lung cancer cells." in: Cancer research, Vol. 67, Issue 2, pp. 643-50, (2007) (PubMed).

Jeong, Kim, Kim, Son, Park, Lim, Yoon, Ryu: "Trimeric structure of PRL-1 phosphatase reveals an active enzyme conformation and regulation mechanisms." in: Journal of molecular biology, Vol. 345, Issue 2, pp. 401-13, (2004) (PubMed).

Werner, Lee, DeCamp, Crowell, Randall, Crowell: "Enhanced cell cycle progression and down regulation of p21(Cip1/Waf1) by PRL tyrosine phosphatases." in: Cancer letters, Vol. 202, Issue 2, pp. 201-11, (2003) (PubMed).

Wang, Kirby, Herbst: "The tyrosine phosphatase PRL-1 localizes to the endoplasmic reticulum and the mitotic spindle and is required for normal mitosis." in: The Journal of biological chemistry, Vol. 277, Issue 48, pp. 46659-68, (2002) (PubMed).

Peng, Genin, Spinner, Diamond, Taub: "The gene encoding human nuclear protein tyrosine phosphatase, PRL-1. Cloning, chromosomal localization, and identification of an intron enhancer." in: The Journal of biological chemistry, Vol. 273, Issue 27, pp. 17286-95, (1998) (PubMed).

Synonyms and alternative names related to PTP4A1

protein tyrosine phosphatase type IVA, member 1 (PTP4A1), protein tyrosine phosphatase type IVA, member 1 L homeolog (ptp4a1.L), protein tyrosine phosphatase type IVA, member 1 (ptp4a1), protein tyrosine phosphatase type IVA, member 1 (Ptp4a1), protein tyrosine phosphatase 4a1 (Ptp4a1), AA415290, AU019864, C130021B01, DKFZp459E022, fb54d08, fc01c04, hh72, HH72, MGC79517, MGC83351, prl-1, PRL-1, Prl-1, prl1, PRL1, ptp(caax1), PTP(CAAX1), ptp4a1, Ptp4a1, PTP4A1, ptpcaax1, PTPCAAX1, wu:fb54d08, wu:fc01c04, zgc:101726

Protein level used designations for PTP4A1

  • protein tyrosine phosphatase type IVA 1
  • protein tyrosine phosphatase type IVA, member 1
  • PRL-1
  • Protein tyrosine phosphatase type IVA 1
  • protein-tyrosine phosphatase 4a1
  • protein-tyrosine phosphatase of regenerating liver 1
  • protein tyrosine phosphatase type IVA protein 1
  • protein tyrosine phosphatase 4a1
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