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RAS Guanyl Releasing Protein 2 (Calcium and DAG-Regulated) Products

(RAS Guanyl Releasing Protein 2 (Calcium and DAG-Regulated) (RASGRP2))

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The protein encoded by this gene is a brain-enriched nucleotide exchanged factor that contains an N-terminal GEF domain, 2 tandem repeats of EF-hand calcium-binding motifs, and a C-terminal diacylglycerol/phorbol ester-binding domain. This protein can activate small GTPases, including RAS and RAP1/RAS3. The nucleotide exchange activity of this protein can be stimulated by calcium and diacylglycerol. Three alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008].

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Featured RAS Guanyl Releasing Protein 2 (Calcium and DAG-Regulated) Categories

RAS Guanyl Releasing Protein 2 (Calcium and DAG-Regulated) Antibodies

High quality antibodies with extensive validation data.

RAS Guanyl Releasing Protein 2 (Calcium and DAG-Regulated) Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended RAS Guanyl Releasing Protein 2 (Calcium and DAG-Regulated) Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IF, IHC (p)
Validations
  • (4)
Cat. No. ABIN656117
Quantity 400 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (1)
  • (3)
Cat. No. ABIN523644
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (2)
Cat. No. ABIN564429
Quantity 50 μL
Datasheet Datasheet

Recommended RAS Guanyl Releasing Protein 2 (Calcium and DAG-Regulated) ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6959050
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Sandwich ELISA
Validations
Cat. No. ABIN422861
Quantity 96 tests
Datasheet Datasheet

Recommended RAS Guanyl Releasing Protein 2 (Calcium and DAG-Regulated) Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1317498
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1317496
Quantity 25 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1317497
Quantity 25 μg
Datasheet Datasheet

Latest Publications for our RAS Guanyl Releasing Protein 2 (Calcium and DAG-Regulated) products

Andersson, Nilsson, Fagerberg, Hallström, Sundström, Danielsson, Edlund, Uhlen, Asplund: "The transcriptomic and proteomic landscapes of bone marrow and secondary lymphoid tissues." in: PLoS ONE, Vol. 9, Issue 12, pp. e115911, (2014) (PubMed).

Lima, Parreira, Devuyst, Caplanusi, Nkuli, Marien, Van Der Smissen, Alves, Verroust, Christensen, Terzi, Matter, Balda, Pierreux, Courtoy: "ZONAB promotes proliferation and represses differentiation of proximal tubule epithelial cells." in: Journal of the American Society of Nephrology : JASN, Vol. 21, Issue 3, pp. 478-88, (2010) (PubMed).

Boudreaux, Catalfamo, Klok: "Calcium-diacylglycerol guanine nucleotide exchange factor I gene mutations associated with loss of function in canine platelets." in: Translational research : the journal of laboratory and clinical medicine, Vol. 150, Issue 2, pp. 81-92, (2007) (PubMed).

Katagiri, Shimonaka, Kinashi: "Rap1-mediated lymphocyte function-associated antigen-1 activation by the T cell antigen receptor is dependent on phospholipase C-gamma1." in: The Journal of biological chemistry, Vol. 279, Issue 12, pp. 11875-81, (2004) (PubMed).

Eto, Murphy, Kerrigan, Bertoni, Stuhlmann, Nakano, Leavitt, Shattil: "Megakaryocytes derived from embryonic stem cells implicate CalDAG-GEFI in integrin signaling." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 99, Issue 20, pp. 12819-24, (2002) (PubMed).

Guo, Kumahara, Saffen: "A CalDAG-GEFI/Rap1/B-Raf cassette couples M(1) muscarinic acetylcholine receptors to the activation of ERK1/2." in: The Journal of biological chemistry, Vol. 276, Issue 27, pp. 25568-81, (2001) (PubMed).

Toki, Kawasaki, Tashiro, Housman, Graybiel: "Guanine nucleotide exchange factors CalDAG-GEFI and CalDAG-GEFII are colocalized in striatal projection neurons." in: The Journal of comparative neurology, Vol. 437, Issue 4, pp. 398-407, (2001) (PubMed).

Synonyms and alternative names related to RAS Guanyl Releasing Protein 2 (Calcium and DAG-Regulated)

RAS guanyl releasing protein 2 (RASGRP2), RAS guanyl releasing protein 2 (calcium and DAG-regulated) S homeolog (rasgrp2.S), RAS, guanyl releasing protein 2 (Rasgrp2), RAS guanyl releasing protein 2 (Rasgrp2), RAS guanyl releasing protein 2 (calcium and DAG-regulated) L homeolog (rasgrp2.L), CALDAG-GEFI, CalDAG-GEFI, Caldaggef1, CDC25L, RASGRP2, rasgrp2, xrasgrp2

Protein level used designations for RAS Guanyl Releasing Protein 2 (Calcium and DAG-Regulated)

  • F25B3.3 kinase-like protein
  • RAS guanyl nucleotide-releasing protein 2
  • RAS guanyl-releasing protein 2
  • calcium and DAG-regulated guanine nucleotide exchange factor I
  • calcium and diacylglycerol-regulated guanine nucleotide exchange factor I
  • cdc25-like protein
  • guanine exchange factor MCG7
  • hCDC25L
  • RAS guanyl-releasing protein 2-A
  • RAS guanyl releasing protein 2
  • RAS guanyl releasing protein 2, isoform 3
  • CalDAG-GEFI
  • F25B3.3 kinase like protein
  • RAP 1A protein-specific guanine nucleotide exchange factor 1
  • RAS, guanyl releasing protein 2; RAP 1A protein-specific guanine nucleotide exchange factor 1; CalDAG-GEFI
  • RAS, guanyl releasing protein 2
  • calDAG-GEFI
  • calcium diacylglycerol guanine nucleotide exchange factor I
  • RAS guanyl-releasing protein 2-B
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