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anti-Human GUCA1C Antibodies:
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Human Polyclonal GUCA1C Primary Antibody for WB - ABIN1881400
Stephen, Palczewski, Sousa: The crystal structure of GCAP3 suggests molecular mechanism of GCAP-linked cone dystrophies. in Journal of molecular biology 2006
Show all 3 Pubmed References
Examination of larval and adult stages of the developing zebrafish retina indicates that GCAP3 is first expressed in a non-myristoylated form, but is finally present in the adult retina as a myristoylated protein.
Data show that high guanylate cyclase activities in larval eye preparations and the precisely controlled coexpression of guanylate cyclases and GCAPs 3, 4, and 7 coincide with the onset of visual function at 3-4 days post fertilization.
Results report the crystal structure of unmyristoylated human guanylate cyclase-activating protein 3 (show HSPB3 Antibodies) (GCAP3) with calcium bound.
Stimulates guanylyl cyclase 1 (GC1) and GC2 when free calcium ions concentration is low and inhibits guanylyl cyclases when free calcium ions concentration is elevated. This Ca(2+)- sensitive regulation of guanylyl cyclase (GC) is a key event in recovery of the dark state of rod photoreceptors following light exposure.
guanylate cyclase activator 1C
, GCAP 3
, guanylyl cyclase-activating protein 3