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|Antigen||Lysine (K)-Specific Demethylase 1A (KDM1A) Antibodies|
Dot Blot (DB), Immunocytochemistry (ICC), Western Blotting (WB)
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|Cross-Reactivity||Human, Mouse (Murine), Rat (Rattus)|
|Cross-Reactivity (Details)||Other species not studied.|
|Purification||Protein G affinity chromatography|
|Immunogen||AOF2 antibody was raised in mouse using recombinant Human Amine Oxidase (Flavin Containing) Domain 2 (Aof2)|
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|Alternative Name||AOF2 (KDM1A Antibody Abstract)|
|Background||This gene encodes a nuclear protein containing a SWIRM domain, a FAD-binding motif, and an amine oxidase domain. This protein is a component of several histone deacetylase complexes, though it silences genes by functioning as a histone demethylase. Alternate splicing has been observed, however, not all transcript variants have been fully characterized. Synonyms: Monoclonal AOF2 antibody, Anti-AOF2 antibody, Flavin-containing amine oxidase domain-containing protein 22 antibody, LSD1 antibody, BHC110 antibody, KIAA0601 antibody, RP1-184J9.1 antibody.|
|Pathways||Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, Negative Regulation of intrinsic apoptotic Signaling|
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WB: 0.2-2 µg/mL, ICC: 2-100 µg/mL
Optimal conditions should be determined by the investigator.
|Restrictions||For Research Use only|
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|Buffer||AOF2 antibody in PBS (3.0 mM KCl, 1.5 mM KH2 PO4 , 140 mM NaCl, 8.0 mM Na2 HPO4 (pH 7.4)) containing 1 % bovine serum albumin (BSA) and 0.05 % sodium azide (NaN3 ).|
|Precaution of Use||This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.|
Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.
|Storage Comment||Store at 2-8 °C for up to one year. We recommend long term storage at -20 °C.|
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