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TXK tyrosine Kinase ELISA Kits

2 TXK tyrosine Kinase (TXK) ELISA Kits from 2 manufacturers are available on www.antibodies-online.com.

2 results:

TXK tyrosine Kinase (TXK) ELISA Kit ELISA Kit

TXK Reactivity: Human Colorimetric Sandwich ELISA 0.313 ng/mL - 20 ng/mL Plasma, Serum, Tissue Homogenate
Catalog No. ABIN6971009
$638.85
Plus shipping costs $45.00
96 tests
local_shipping Shipping to: United States
Delivery in 10 to 13 Business Days

TXK tyrosine Kinase (TXK) ELISA Kit ELISA Kit

TXK Reactivity: Human pTyr Colorimetric Sandwich ELISA Cell Lysate, Tissue Lysate
Catalog No. ABIN4886333
$480.70
Plus shipping costs $45.00
96 tests (More quantities available)
local_shipping Shipping to: United States
Delivery in 2 to 3 Business Days
  • Type Kit
    • Kit
  • Target TXK tyrosine Kinase (TXK)
    • TXK tyrosine Kinase (TXK)
    • Interferon gamma (IFNG)
    • Histone 3 (H3)
    • Epidermal Growth Factor Receptor (EGFR)
    • Interleukin 10 (IL10)
    • Interleukin 4 (IL4)
    • Tumor Necrosis Factor alpha (TNF)
    • Interleukin 6 (IL6)
    • Tumor Protein P53 (TP53)
    • Interleukin 1, beta (IL1B)
    • Interleukin 2 (IL2)
    • Transforming Growth Factor, beta 1 (TGFB1)
    • IgG
    • Albumin (ALB)
    • Leptin (LEP)
    • Follicle-Stimulating Hormone (FSH)
    • Interleukin 8 (IL8)
    • Jun Proto-Oncogene (JUN)
    • IgA
    • Interleukin 1 alpha (IL1A)
    • Insulin-Like Growth Factor 1 (IGF1)
    • Interleukin 13 (IL13)
    • Interleukin 17A (IL17A)
    • Vascular Cell Adhesion Molecule 1 (VCAM1)
    • Insulin (INS)
    • Adiponectin (ADIPOQ)
    • Chemokine (C-C Motif) Ligand 5 (CCL5)
    • Interleukin 5 (IL5)
    • Chemokine (C-C Motif) Ligand 2 (CCL2)
    • Metalloproteinase Inhibitor 2 (TIMP2)
    • Cystatin C (CST3)
    • Interleukin 12 (IL12)
    • Platelet-Derived Growth Factor beta Polypeptide (PDGFB)
    • Annexin A5 (ANXA5)
    • Cortisol
    • Retinol Binding Protein 4, Plasma (RBP4)
    • Interleukin 1 Receptor Antagonist (IL1RN)
    • Luteinizing Hormone (LH)
    • Prolactin (PRL)
    • Resistin (RETN)
    • Complement Component 3 (C3)
    • Fas Ligand (TNF Superfamily, Member 6) (FASL)
    • Insulin-Like Growth Factor 2 (IGF2)
    • Serum Amyloid A (SAA)
    • Thyroxine T4 (T4)
    • Epidermal Growth Factor (EGF)
    • Erythropoietin (EPO)
    • IgM
    • Matrix Metallopeptidase 9 (Gelatinase B, 92kDa Gelatinase, 92kDa Type IV Collagenase) (MMP9)
    • Mitogen-Activated Protein Kinase 14 (MAPK14)
    • Nuclear Factor-KB P65 (NFkBP65)
  • Application
    • ELISA
  • Reactivity
    • Human
  • Images available
  • Method Type
    • Sandwich ELISA
  • Analytical Method
    • Quantitative
    • Semi-Quantitative
  • Detection Method
    • Colorimetric
  • Plate
    • Pre-coated
  • Binding Specificity
    • pTyr
  • Sample
    • Cell Lysate
    • Plasma
    • Serum
    • Tissue Homogenate
    • Tissue Lysate

TXK tyrosine Kinase (TXK) Antigen Profile

Protein Summary

Non-receptor tyrosine kinase that plays a redundant role with ITK in regulation of the adaptive immune response. Regulates the development, function and differentiation of conventional T- cells and nonconventional NKT-cells. When antigen presenting cells (APC) activate T-cell receptor (TCR), a series of phosphorylation lead to the recruitment of TXK to the cell membrane, where it is phosphorylated at Tyr-420. Phosphorylation leads to TXK full activation. Contributes also to signaling from many receptors and participates in multiple downstream pathways, including regulation of the actin cytoskekleton. Like ITK, can phosphorylate PLCG1, leading to its localization in lipid rafts and activation, followed by subsequent cleavage of its substrates. In turn, the endoplasmic reticulum releases calcium in the cytoplasm and the nuclear activator of activated T-cells (NFAT) translocates into the nucleus to perform its transcriptional duty. With PARP1 and EEF1A1, TXK forms a complex that acts as a T-helper 1 (Th1) cell- specific transcription factor and binds the promoter of IFNG to directly regulate its transcription, and is thus involved importantly in Th1 cytokine production. Phosphorylates both PARP1 and EEF1A1. Phosphorylates also key sites in LCP2 leading to the up-regulation of Th1 preferred cytokine IL-2. Phosphorylates 'Tyr- 201' of CTLA4 which leads to the association of PI-3 kinase with the CTLA4 receptor.

Alternative names and synonyms associated with TXK tyrosine Kinase (TXK)

  • TXK tyrosine kinase (TXK) antibody
  • TXK tyrosine kinase (Txk) antibody
  • tyrosine-protein kinase TXK (LOC100544958) antibody
  • A130089B16Rik antibody
  • Btkl antibody
  • PSCTK5 antibody
  • PTK4 antibody
  • Rlk antibody
  • TKL antibody

Protein level used designations for TXK tyrosine Kinase (TXK) ELISA Kits

PTK4 protein tyrosine kinase 4 , protein-tyrosine kinase 4 , resting lymphocyte kinase , tyrosine kinase , tyrosine-protein kinase TXK , PTK-RL-18 , TXK tyrosine kinase , tyrosine-protein kinase TXK-like , LOW QUALITY PROTEIN: tyrosine-protein kinase TXK

GENE ID SPECIES
7294 Homo sapiens
22165 Mus musculus
305311 Rattus norvegicus
444993 Sus scrofa
461344 Pan troglodytes
482139 Canis lupus familiaris
504782 Bos taurus
705104 Macaca mulatta
770387 Gallus gallus
100019276 Monodelphis domestica
100054343 Equus caballus
100341671 Oryctolagus cuniculus
100397226 Callithrix jacchus
100455862 Pongo abelii
100464564 Ailuropoda melanoleuca
100544958 Meleagris gallopavo
100598060 Nomascus leucogenys
100722451 Cavia porcellus

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