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Human Polyclonal DRD5 Primary Antibody for IF (p), IHC (p) - ABIN733868
Xu, Wang, Chen, Chen, Li, Shao, Li, Lu, Zhou: Dopamine D1 receptor activation induces dehydroepiandrosterone sulfotransferase (SULT2A1) in HepG2 cells. in Acta pharmacologica Sinica 2014
Mouse (Murine) Monoclonal DRD5 Primary Antibody for ICC, IF - ABIN258727
Luedtke, Griffin, Conroy, Jin, Pinto, Sesack: Immunoblot and immunohistochemical comparison of murine monoclonal antibodies specific for the rat D1a and D1b dopamine receptor subtypes. in Journal of neuroimmunology 1999
DRD5 (dopamine receptor D5) agonists were potent inhibitors of pituitary tumor growth.
Meta-analysis of data from six sites of the International Multicentre persistent ADHD CollaboraTion tested the association of the common DRD5 alleles with categorically defined ADHD and with inattentive and hyperactive/impulsive symptom counts, found evidence that none of the common DRD5 alleles are associated with ADHD risk or ADHD symptom counts in adults.
Study investigated the contribution of DRD5 gene variants in the symptoms of attention-deficit/hyperactivity disorder (ADHD): 19 exonic variants were monomorphic in the Indo (show IDO1 Antibodies)-Caucasoid individuals. rs6283 "C" and rs113828117 "A" exhibited significant higher occurrence in families with ADHD probands. Early and late onset groups exhibited significantly different genotypic frequencies.
This study reveled that DRD5 are up regulation in CD4 (show CD4 Antibodies)+ T effector and regulatory cells in patient with multiple sclerosis.
DRD5 gene expression reduction in breast cancer patients after spiritual intervention
Conserved residues in intracellular loop 1 and transmembrane region 2 of DRD1 (show DRD1 Antibodies) and DRD5 are essential in ligand binding and signal transduction.
D1R and D5R colocalize in renal proximal tubule cells and physically interact in second messenger coupling pathways and heterologous receptor interaction between the two receptors.
This study shown DRD5 to be the risk factor for attention deficit/hyperactivity disorder.
LRs are essential not only for the proper membrane distribution and maintenance of AC5/6 activity but also for the regulation of D1R- and D5R-mediated AC signaling.
We found significant negative correlations regarding the expression of the genes COMT, MAOB, DRD4, DRD5 and FOS, indicating that increased schizotypy coincides with higher levels of dopaminergic dysregulation on the mRNA-level.
Findings demonstrate the relevant contribution of dopamine receptor D5 (D5R) in memory and suggest a functional interaction of D5R with hippocampal glutamatergic pathways.
Data provides evidence that forebrain D5R activation plays a unique role in spatial learning and memory in conjunction with D1R (show DRD1 Antibodies) activation
CCKBR and D5R synergistically interact in the kidney, which may contribute to the maintenance of normal sodium balance following an increase in sodium intake
We suggest that the ability of the dopamine D5 receptor to negatively regulate the renal NADPH oxidase (show NOX4 Antibodies) activity and AT1R (show AGTRAP Antibodies) function may have important implications in the pathogenesis of salt-sensitive blood pressure.
This study demonstrated that D5R stimulation contributes to an efficient CD4(+)T-cell-induced early ERK1/2 phosphorylation, and differentiation.
The renal D5R protein upregulation was not caused by increased transcription because renal mRNA expression of D5R was similar in D3(-/-) and D3(+/+) mice.
This study demonistrated that the dopamine D5 receptor as a regulator of BDNF (show BDNF Antibodies) and Akt (show AKT1 Antibodies) signalling in rodent prefrontal cortex.
SNX1 (show SNX1 Antibodies) has a crucial role in D(5)R trafficking and SNX1 (show SNX1 Antibodies) depletion results in D(5)R dysfunction and thus may represent a novel mechanism for the pathogenesis of essential hypertension
By contributing to CD4(+) T cell activation and differentiation to Th17 phenotype, D5R expressed on DCs is able to modulate the development of an autoimmune response in vivo.
We propose that ciliary DR5 (show TNFRSF10B Antibodies) has functional chemo- and mechano-sensory roles in endothelial cells.
There were significant differences in the allelic frequencies among Bos taurus and Bos indicus breeds of different temperament for the DRD1 (show DRD1 Antibodies), DRD4 (show DRD4 Antibodies), and DRD5 markers.
these data provide evidence that functional D1/D5 receptors are expressed in the internal globus pallidus and the substantia nigra pars (show EPRS Antibodies) reticulata in both normal and parkinsonian states in monkeys
In the basolateral amygdala, the D1R (show DRD1 Antibodies) subtypes colocalize in dendritic spines and terminals, with D(5) predominant in terminals. There were similarities between the primates and rats, such as more prominent D(5) localization to presynaptic structures.
This gene encodes the D5 subtype of the dopamine receptor. The D5 subtype is a G-protein coupled receptor which stimulates adenylyl cyclase. This receptor is expressed in neurons in the limbic regions of the brain. It has a 10-fold higher affinity for dopamine than the D1 subtype. Pseudogenes related to this gene reside on chromosomes 1 and 2.
dopamine receptor D5
, D(1B) dopamine receptor-like
, D(1B) dopamine receptor
, D1beta dopamine receptor
, d(5) dopamine receptor
, dopamine D5 receptor
, dopamine receptor D1B
, dopamine receptor 5
, D(5) dopamine receptor
, D1b dopamine receptor
, D5 dopamine receptor
, dopamine D1B receptor