anti-Human ASS1 antibody for Immunohistochemistry (Paraffin-embedded Sections)

Recommended ASS1 Antibody (supplied by: Log in to see )

Antigen
Argininosuccinate Synthase 1 (ASS1) Antibodies
  • ASS
  • CTLN1
  • AA408052
  • Ass-1
  • fold
  • ASSA
  • Ass
  • ass
  • zgc:92051
  • wu:fb95a04
  • wu:fc01e08
  • argininosuccinate synthase 1
  • argininosuccinate synthetase 1
  • argininosuccinate synthase 1 S homeolog
  • ASS1
  • Ass1
  • ass1.S
  • ass1
Epitope
AA 280-310, C-Term
25
11
10
7
4
4
2
2
2
2
2
1
1
1
1
1
Reactivity
Human
139
61
46
38
9
7
2
2
1
1
1
Host
Rabbit
65
49
25
Clonality
Polyclonal
Conjugate
This ASS1 antibody is un-conjugated
7
5
5
4
4
3
2
2
2
2
2
2
2
2
2
2
2
1
Application
Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
126
94
67
46
39
28
25
22
5
3
2
Supplier
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Catalog No. ABIN950542
$ 390.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
12.35866 ABIN4281472 ICC IF IHC IHC (p) WB Rabbit IgG Log in to see Polyclonal 1
12.35866 ABIN615430 EIA IHC (p) IP WB Goat Internal Region Log in to see Polyclonal 0
12.35866 ABIN314255 IHC (p) IHC ELISA WB Goat Log in to see Polyclonal 3
12.35866 ABIN441522 IHC (p) IHC WB Rabbit IgG Center Log in to see Polyclonal 0
12.35866 ABIN4281473 ICC IF IHC IHC (p) WB Rabbit IgG Log in to see Polyclonal 0
1 ABIN656537 FACS IHC (p) WB Rabbit Ig Fraction AA 281-310, C-Term Log in to see Polyclonal 0
1 ABIN489997 ELISA IHC IHC (p) IP WB Goat AA 196-212 Log in to see Polyclonal 0
1 ABIN320629 IHC IHC (p) WB Rabbit IgG N-Term Log in to see Polyclonal 0
1 ABIN320630 IHC IHC (p) WB Rabbit IgG C-Term Log in to see Polyclonal 0
1 ABIN1105455 EIA IHC (p) WB Mouse IgG1 Log in to see 2C10 1
1 ABIN2855014 IHC (p) WB Rabbit IgG Center Log in to see Polyclonal 0
1 ABIN5553322 EIA IF IHC (p) IP WB Goat Internal Region Log in to see Polyclonal 0
1 ABIN5533736 FACS IHC (p) WB Rabbit Ig Fraction AA 281-310, C-Term Log in to see Polyclonal 0
1 ABIN1731998 IHC (p) IP ELISA WB Goat Internal Region Log in to see Polyclonal 0
1 ABIN1832871 IHC IHC (p) WB Rabbit IgG AA 1-198 Log in to see Polyclonal 0
1 ABIN1960124 ELISA IHC IHC (p) WB Mouse IgG1 Log in to see 2C10 0
1 ABIN1960123 ELISA FACS IHC IHC (p) Mouse IgG1 Log in to see 2B10 0
1 ABIN1806002 FACS IHC IHC (p) WB Rabbit AA 281-310 Log in to see Polyclonal 0
1 ABIN1976828 FACS IF IHC IHC (p) WB Rabbit AA 192-221 Log in to see Polyclonal 0
1 ABIN2961948 ICC FACS IHC (p) ELISA WB Mouse IgG1 Log in to see 2B10 0

General

Antigen Argininosuccinate Synthase 1 (ASS1) Antibodies
Epitope AA 280-310, C-Term
(25), (11), (10), (7), (4), (4), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1)
Reactivity Human
(139), (61), (46), (38), (9), (7), (2), (2), (1), (1), (1)
Host Rabbit
(65), (49), (25)
Clonality
Polyclonal
Conjugate This ASS1 antibody is un-conjugated
(7), (5), (5), (4), (4), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1)
Application Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(126), (94), (67), (46), (39), (28), (25), (22), (5), (3), (2)
Pubmed 5 references available
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Product Details anti-ASS1 Antibody

Target Details ASS1 Application Details Handling References for anti-ASS1 antibody (ABIN950542) Images
Specificity This antibody reacts to ASS1.
Cross-Reactivity (Details) Species reactivity (tested):Human.
Purification Affinity chromatography on Protein A
Immunogen KLH conjugated synthetic peptide between 280-310 amino acids from the C-terminal region of human ASS1
Isotype Ig Fraction

Target Details ASS1

Product Details anti-ASS1 Antibody Application Details Handling References for anti-ASS1 antibody (ABIN950542) Images back to top
Antigen
Alternative Name ASS1 (ASS1 Antibody Abstract)
Background The protein encoded by this gene catalyzes the penultimate step of the arginine biosynthetic pathway. There are approximately 10 to 14 copies of this gene including the pseudogenes scattered across the human genome, among which the one located on chromosome 9 appears to be the only functional gene for argininosuccinate synthetase. Mutations in the chromosome 9 copy of ASS cause citrullinemia. Two transcript variants encoding the same protein have been found for this gene.Synonyms: Argininosuccinate synthase, Citrulline-aspartate ligase
Gene ID 445
NCBI Accession NP_000041
Pathways Response to Growth Hormone Stimulus, Cellular Response to Molecule of Bacterial Origin

Application Details

Product Details anti-ASS1 Antibody Target Details ASS1 Handling References for anti-ASS1 antibody (ABIN950542) Images back to top
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only

Handling

Product Details anti-ASS1 Antibody Target Details ASS1 Application Details References for anti-ASS1 antibody (ABIN950542) Images back to top
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS containing 0.09 % (W/V) sodium azide as preservative
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

References for anti-ASS1 antibody (ABIN950542)

Product Details anti-ASS1 Antibody Target Details ASS1 Application Details Handling Images back to top
Background publications

Hozyasz, Mostowska, Wojcicki, Lianeri, Jagodzinski: "Polymorphic variants of genes related to arginine metabolism and the risk of orofacial clefts." in: Archives of oral biology, Vol. 55, Issue 11, pp. 861-6, 2010

Kobayashi, Masuda, Nakayama, Ichikawa, Satow, Shitashige, Honda, Yamaguchi, Shoji, Tochigi, Morioka, Toyama, Hirohashi, Kawai, Yamada: "Reduced argininosuccinate synthetase is a predictive biomarker for the development of pulmonary metastasis in patients with osteosarcoma." in: Molecular cancer therapeutics, Vol. 9, Issue 3, pp. 535-44, 2010

Bailey, Xie, Do, Montpetit, Diaz, Mohan, Keavney, Yusuf, Gerstein, Engert, Anand: "Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study." in: Diabetes Care, Vol. 33, Issue 10, pp. 2250-3, 2010

Tsai, Aiba, Lee, Feun, Savaraj, Kuo: "Resistance to arginine deiminase treatment in melanoma cells is associated with induced argininosuccinate synthetase expression involving c-Myc/HIF-1alpha/Sp4." in: Molecular cancer therapeutics, Vol. 8, Issue 12, pp. 3223-33, 2009

Talmud, Drenos, Shah, Shah, Palmen, Verzilli, Gaunt, Pallas, Lovering, Li, Casas, Sofat, Kumari, Rodriguez, Johnson, Newhouse, Dominiczak, Samani, Caulfield, Sever, Stanton, Shields, Padmanabhan et al.: "Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip. ..." in: American journal of human genetics, Vol. 85, Issue 5, pp. 628-42, 2009

Images

Product Details anti-ASS1 Antibody Target Details ASS1 Application Details Handling References for anti-ASS1 antibody (ABIN950542) back to top
Supplier Images
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-Argininosuccinate Synthase 1 (ASS1) (AA 280-310), (C-Term) antibody (ABIN950542) ASS1 Antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin e...
Western Blotting (WB) image for anti-Argininosuccinate Synthase 1 (ASS1) (AA 280-310), (C-Term) antibody (ABIN950542) ASS1 Antibody (C-term) western blot analysis in Jurkat cell line lysates (35µg/lane)....
Western Blotting (WB) image for anti-Argininosuccinate Synthase 1 (ASS1) (AA 280-310), (C-Term) antibody (ABIN950542) Western blot analysis of ASS1 (arrow) using rabbit polyclonal ASS1 Antibody (C-term) ...