Ras Homolog Gene Family, Member A Products
(Ras Homolog Gene Family, Member A (RHOA))
Categories
Regulates a signal transduction pathway linking plasma membrane receptors to the assembly of focal adhesions and actin stress fibers. Involved in a microtubule-dependent signal that is required for the myosin contractile ring formation during cell cycle cytokinesis. Plays an essential role in cleavage furrow formation. Required for the apical junction formation of keratinocyte cell-cell adhesion. Serves as a target for the yopT cysteine peptidase from Yersinia pestis, vector of the plague, and Yersinia pseudotuberculosis, which causes gastrointestinal disorders. Stimulates PKN2 kinase activity. May be an activator of PLCE1. Activated by ARHGEF2, which promotes the exchange of GDP for GTP. Essential for the SPATA13-mediated regulation of cell migration and adhesion assembly and disassembly. The MEMO1-RHOA- DIAPH1 signaling pathway plays an important role in ERBB2- dependent stabilization of microtubules at the cell cortex. It controls the localization of APC and CLASP2 to the cell membrane, via the regulation of GSK3B activity. In turn, membrane-bound APC allows the localization of the MACF1 to the cell membrane, which is required for microtubule capture and stabilization.
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Featured Ras Homolog Gene Family, Member A Categories
Ras Homolog Gene Family, Member A Antibodies
High quality antibodies with extensive validation data.
Ras Homolog Gene Family, Member A ELISA Kits
Reliable ELISA kits for a wide range of species.
Ras Homolog Gene Family, Member A Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended Ras Homolog Gene Family, Member A Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC (p), IF
Validations
- (3)
- (6)
Cat. No.
ABIN559931
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC
Validations
- (6)
Cat. No.
ABIN351037
Quantity
500 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC (p), PLA
Validations
- (6)
Cat. No.
ABIN559932
Quantity
100 μg
Datasheet
Datasheet
Recommended Ras Homolog Gene Family, Member A ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
- (1)
Cat. No.
ABIN6959052
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6969836
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6959051
Quantity
96 tests
Datasheet
Datasheet
Recommended Ras Homolog Gene Family, Member A Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN7124783
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN7124784
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1318004
Quantity
10 μg
Datasheet
Datasheet
Latest Publications for our Ras Homolog Gene Family, Member A products
: "Evaluation of the Rho A/Rho-kinase pathway in the uterus of the rat model of polycystic ovary syndrome." in: Reproductive biology, (2019) (PubMed).: "Elevated BMP and mechanical signaling through YAP1/RhoA Poises FOP Mesenchymal Progenitors for Osteogenesis." in: Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, (2019) (PubMed).
: "miR-31-5p Is a LIPUS-Mechanosensitive MicroRNA that Targets HIF-1α Signaling and Cytoskeletal Proteins." in: International journal of molecular sciences, Vol. 20, Issue 7, (2019) (PubMed).
: "Fasudil attenuates soluble fms-like tyrosine kinase-1 (sFlt-1)-induced hypertension in pregnant mice through RhoA/ROCK pathway." in: Oncotarget, Vol. 8, Issue 61, pp. 104104-104112, (2017) (PubMed).
: "Role of RhoA/MERK1/ERK1/2/iNOS signaling in ocular ischemic syndrome." in: Graefe's archive for clinical and experimental ophthalmology, Vol. 254, Issue 11, pp. 2217-2226, (2016) (PubMed).
: "HSF1 Relieves Amyloid-?-Induced Cardiomyocytes Apoptosis." in: Cell biochemistry and biophysics, (2015) (PubMed).
: "RhoA is associated with invasion and poor prognosis in colorectal cancer." in: International journal of oncology, Vol. 48, Issue 2, pp. 714-22, (2015) (PubMed).
: "Relationship of RhoA signaling activity with ezrin expression and its significance in the prognosis for breast cancer patients." in: Chinese medical journal, Vol. 126, Issue 2, pp. 242-7, (2013) (PubMed).
: "Rho GTPases modulate entry of Ebola virus and vesicular stomatitis virus pseudotyped vectors." in: Journal of virology, Vol. 83, Issue 19, pp. 10176-86, (2009) (PubMed).
: "Serine phosphorylation negatively regulates RhoA in vivo." in: The Journal of biological chemistry, Vol. 278, Issue 21, pp. 19023-31, (2003) (PubMed).
Synonyms and alternative names related to Ras Homolog Gene Family, Member A
ras homolog family member A (RHOA), ras homolog family member A (Rhoa), ras homolog family member A S homeolog (rhoa.S), ras homolog family member A (rhoa), ras homolog family member A L homeolog (rhoa.L), ras homolog gene family, member Aa (rhoaa), ras homolog family member Ca (rhoca), ARH12, arh12, ARHA, Arha, arha, Arha1, Arha2, arha2, ARHC, RHO1, RHO12, rho12, rhoa, Rhoa, rhoae, RHOH12, rhoh12, wu:fa66g04, wu:fb26g07, xrhoa, zgc:64015, zgc:66058, zgc:85805Protein level used designations for Ras Homolog Gene Family, Member A
- Aplysia ras-related homolog 12
- h12
- oncogene RHO H12
- ras homolog gene family, member A
- rho cDNA clone 12
- small GTP binding protein RhoA
- transforming protein RhoA
- Ras family member A
- Rho family GTPase
- aplysia ras-related homolog A
- aplysia ras-related homolog A1
- aplysia ras-related homolog A2
- ras homolog A1
- ras homolog A2
- ras homolog gene family, member A1
- ras homolog gene family, member A2
- plysia ras-related homolog A2
- rho1 GTP-binding protein
- gb
- p21
- RhoA GTPase
- Rho A
- ras homolog family member Ca
- ras homolog gene family, member Ae
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