anti-Human FGFR1 antibody for Immunohistochemistry (Paraffin-embedded Sections)

Recommended FGFR1 Antibody (supplied by: Log in to see )

Antigen
Fibroblast Growth Factor Receptor 1 (FGFR1) Antibodies
  • FGFR
  • fgfr
  • X1FGFR
  • XFGFR-1
  • XFGFRA2
  • bfgfr
  • cek
  • fgfr1
  • flg
  • flt-2
  • flt2
  • kal2
  • ogd
  • xfgfr1
  • CG7223
  • CT22273
  • CT39172
  • DFGF-R1
  • DFGF-R2
  • DFR-1
  • DFR1
  • DFR1/DFGF-R2
  • DPR3
  • DTRK(FR1)
  • Dfr-1
  • Dfr1
  • DmHD-38
  • Dmel\\CG7223
  • Dtk1
  • EMS2
  • FGF-R2
  • FGFR2
  • FR1
  • Fr1
  • HD-38
  • HTL/FGFR1
  • Htl
  • Tk1
  • dtk1
  • i100
  • i150
  • i79
  • j372
  • cd331
  • fgfbr
  • fgfr-1
  • hbgfr
  • n-sam
  • ach
  • cd333
  • cek2
  • fgfr-3
  • hsfgfr3ex
  • jtk4
  • BFGFR
  • CD331
  • CEK
  • FGFBR
  • FGFR-1
  • FLG
  • FLT-2
  • FLT2
  • HBGFR
  • HH2
  • KAL2
  • N-SAM
  • OGD
  • bFGF-R-1
  • AW208770
  • Eask
  • Fgfr-1
  • Flt-2
  • Hspy
  • FLG-1
  • FGFRI
  • x1fgfr
  • cb231
  • sb:cb231
  • fibroblast growth factor receptor
  • fibroblast growth factor receptor 1 S homeolog
  • basic fibroblast growth factor receptor 1
  • heartless
  • fibroblast growth factor receptor 1
  • fibroblast growth factor receptor 3 (achondroplasia, thanatophoric dwarfism) L homeolog
  • Fibroblast growth factor receptor 1
  • fibroblast growth factor receptor 1 L homeolog
  • fibroblast growth factor receptor 1a
  • FGFR
  • fgfr
  • fgfr1.S
  • CpipJ_CPIJ005849
  • htl
  • fgfr1
  • fgfr3.L
  • FGFR1
  • Fgfr1
  • fgfr1.L
  • fgfr1a
Epitope
AA 19-48, N-Term
62
59
48
45
37
35
34
30
25
23
20
17
17
12
12
11
11
10
9
9
9
9
8
8
7
5
4
4
4
4
4
4
3
3
3
3
3
3
3
3
3
3
3
3
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Human, Mouse (Murine)
625
289
225
21
14
14
11
10
7
6
6
4
2
2
1
Host
Rabbit
427
179
35
Clonality
Polyclonal
Conjugate
This FGFR1 antibody is un-conjugated
36
33
29
24
24
19
9
9
5
5
5
5
5
5
5
5
5
4
4
4
4
4
4
4
4
4
4
Application
Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
547
258
201
103
99
76
71
52
50
21
19
14
10
8
2
1
1
1
Options
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Catalog No. ABIN1882081
$ 335.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
21.579586 ABIN2854680 ICC IF IHC (p) WB Rabbit IgG C-Term Log in to see Polyclonal 0
14.127748 ABIN364422 ELISA IHC IHC (p) WB Goat AA 837-852 Log in to see Polyclonal 0
14.127748 ABIN614919 EIA IHC (p) WB Goat C-Term Log in to see Polyclonal 0
12.579585 ABIN2141086 IHC (p) WB Rabbit IgG pTyr154 Log in to see Polyclonal 0
11.5 ABIN3044410 IHC (p) WB Rabbit IgG AA 806-822, C-Term Log in to see Polyclonal 2
11.127748 ABIN2649245 IHC (p) Mouse IgG2a AA 1-285 Log in to see 09 0
11.127748 ABIN498220 IHC (p) WB Rabbit Log in to see Polyclonal 0
11.127748 ABIN351555 IHC IHC (p) WB Mouse IgG2b Tyr654, pTyr653 Log in to see 0
11.127748 ABIN4909556 IF IHC (p) WB Mouse IgG1 kappa AA 806-842 Log in to see 1440CT772-50-23 0
10 ABIN358128 EIA IHC (p) WB Rabbit Ig Fraction pTyr766 Log in to see Polyclonal 6
10 ABIN652370 FACS IHC (p) WB Rabbit Ig Fraction C-Term Log in to see Polyclonal 0
10 ABIN5534371 FACS IF IHC (p) WB Rabbit Ig Fraction N-Term Log in to see Polyclonal 0
10 ABIN5534376 FACS IHC (p) WB Rabbit Ig Fraction Log in to see Polyclonal 0
8.127748 ABIN742838 IF (p) IHC (p) WB Rabbit IgG pTyr653, pTyr654 Log in to see Polyclonal 0
8.127748 ABIN498838 IHC (p) Rabbit pTyr154 Log in to see Polyclonal 0
8.127748 ABIN2174125 IF (p) IHC (p) WB Rabbit IgG pTyr766 Log in to see Polyclonal 0
8.127748 ABIN498927 IHC (p) Rabbit Log in to see Polyclonal 0
7 ABIN2888659 ELISA IHC IHC (p) WB Rabbit IgG AA 736-785 Log in to see Polyclonal 0
7 ABIN790674 IHC IHC (fro) IHC (p) IP WB Mouse IgG2a N-Term Log in to see M2F12 0
7 ABIN790675 IHC IHC (p) IP WB Mouse IgG2b N-Term Log in to see M 17A3 0

General

Antigen Fibroblast Growth Factor Receptor 1 (FGFR1) Antibodies
Epitope AA 19-48, N-Term
(62), (59), (48), (45), (37), (35), (34), (30), (25), (23), (20), (17), (17), (12), (12), (11), (11), (10), (9), (9), (9), (9), (8), (8), (7), (5), (4), (4), (4), (4), (4), (4), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human, Mouse (Murine)
(625), (289), (225), (21), (14), (14), (11), (10), (7), (6), (6), (4), (2), (2), (1)
Host Rabbit
(427), (179), (35)
Clonality (Clone)
Polyclonal   ( )
Conjugate This FGFR1 antibody is un-conjugated
(36), (33), (29), (24), (24), (19), (9), (9), (5), (5), (5), (5), (5), (5), (5), (5), (5), (4), (4), (4), (4), (4), (4), (4), (4), (4), (4)
Application Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(547), (258), (201), (103), (99), (76), (71), (52), (50), (21), (19), (14), (10), (8), (2), (1), (1), (1)
Pubmed 12 references available
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Product Details anti-FGFR1 Antibody

Target Details FGFR1 Application Details Handling References for anti-FGFR1 antibody (ABIN1882081) Images
Purification This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS. Purified Rabbit Polyclonal Antibody (Pab)
Immunogen This FGFR1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 19~48 amino acids from the N-terminal region of human FGFR1.
Clone RB04521
Plasmids, Primers & others

Target Details FGFR1

Product Details anti-FGFR1 Antibody Application Details Handling References for anti-FGFR1 antibody (ABIN1882081) Images back to top
Antigen
Alternative Name FGFR1 (FGFR1 Antibody Abstract)
Background FGFR1 is a member of the fibroblast growth factor receptor family, where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein consists of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. This particular family member binds both acidic and basic fibroblast growth factors and is involved in limb induction. Mutations in this gene can lead to Pfeiffer syndrome and Jackson-Weiss syndrome. The genomic organization of the gene is very similar to family members 2-4, encompassing 19 exons that are subject to complex alternative splicing, which allows for structural, tissue expression and ligand affinity variations among the isoforms.

Synonyms: FGFR1, BFGFR, CEK, FGFBR, FLG, FLT2, HBGFR, Fibroblast growth factor receptor 1, Basic fibroblast growth factor receptor 1, Fms-like tyrosine kinase 2, N-sam, Proto-oncogene c-Fgr, CD_antigen=CD331, Flags: Precursor
NCBI Accession NP_075593, NP_001167537, NP_075594, NP_001167536, NP_001167535, NP_001167534, NP_001167538, NP_056934, NP_075598
UniProt P11362
Pathways RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Sensory Perception of Sound, Stem Cell Maintenance

Application Details

Product Details anti-FGFR1 Antibody Target Details FGFR1 Handling References for anti-FGFR1 antibody (ABIN1882081) Images back to top
Application Notes FACS: 1:10-50,WB: 1:1000,IHC (p): 1:50-100,IF: 1:50-100
Restrictions For Research Use only

Handling

Product Details anti-FGFR1 Antibody Target Details FGFR1 Application Details References for anti-FGFR1 antibody (ABIN1882081) Images back to top
Format Liquid
Concentration 2 mg/mL
Buffer Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Preservative Sodium azide
Precaution of Use WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

References for anti-FGFR1 antibody (ABIN1882081)

Product Details anti-FGFR1 Antibody Target Details FGFR1 Application Details Handling Images back to top
Product cited in:

Hirata, Katayama, Tsuji, Imura, Natsume, Sugahara, Kunieda, Nakamura, Otsuki: "Homeobox family Hoxc localization during murine palate formation." in: Congenital anomalies, Vol. 56, Issue 4, pp. 172-9, 2016 Method employed by authors: Immunofluorescence (IF)

Mohanan, Temburni, Kappes, Galileo: "L1CAM stimulates glioma cell motility and proliferation through the fibroblast growth factor receptor." in: Clinical & experimental metastasis, Vol. 30, Issue 4, pp. 507-20, 2013

Kamura, Matsumoto, Fukushi, Fujiwara, Iida, Okada, Iwamoto: "Basic fibroblast growth factor in the bone microenvironment enhances cell motility and invasion of Ewing's sarcoma family of tumours by activating the FGFR1-PI3K-Rac1 pathway." in: British journal of cancer, Vol. 103, Issue 3, pp. 370-81, 2010 Method employed by authors: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Page, Ambady, Holmes, Vilner, Kole, Kashpur, Huntress, Vojtic, Whitton, Dominko: "Induction of stem cell gene expression in adult human fibroblasts without transgenes." in: Cloning and stem cells, Vol. 11, Issue 3, pp. 417-26, 2009 Method employed by authors: Immunocytochemistry (ICC)

Mondrinos, Koutzaki, Lelkes, Finck: "A tissue-engineered model of fetal distal lung tissue." in: American journal of physiology. Lung cellular and molecular physiology, Vol. 293, Issue 3, pp. L639-50, 2007 Method employed by authors: Immunocytochemistry (ICC)

Sahni, Francis: "Stimulation of endothelial cell proliferation by FGF-2 in the presence of fibrinogen requires alphavbeta3." in: Blood, Vol. 104, Issue 12, pp. 3635-41, 2004 Method employed by authors: Western Blotting (WB)

Jiao, Greendorfer, Zhang, Zinn, Diglio, Thompson: "Alternatively spliced FGFR-1 isoform signaling differentially modulates endothelial cell responses to peroxynitrite." in: Archives of biochemistry and biophysics, Vol. 410, Issue 2, pp. 187-200, 2003

Fu, Abu-Khalil, Morrison, Geschwind, Kornblum: "Expression patterns of epidermal growth factor receptor and fibroblast growth factor receptor 1 mRNA in fetal human brain." in: The Journal of comparative neurology, Vol. 462, Issue 2, pp. 265-73, 2003

Lundin, Rönnstrand, Cross, Hellberg, Lindahl, Claesson-Welsh: "Differential tyrosine phosphorylation of fibroblast growth factor (FGF) receptor-1 and receptor proximal signal transduction in response to FGF-2 and heparin." in: Experimental cell research, Vol. 287, Issue 1, pp. 190-8, 2003

Kiselyov, Skladchikova, Hinsby, Jensen, Kulahin, Soroka, Pedersen, Tsetlin, Poulsen, Berezin, Bock: "Structural basis for a direct interaction between FGFR1 and NCAM and evidence for a regulatory role of ATP." in: Structure (London, England : 1993), Vol. 11, Issue 6, pp. 691-701, 2003

Baumann, Kunapuli, Tracy, Cowell: "The oncogenic fusion protein-tyrosine kinase ZNF198/fibroblast growth factor receptor-1 has signaling function comparable with interleukin-6 cytokine receptors." in: The Journal of biological chemistry, Vol. 278, Issue 18, pp. 16198-208, 2003

Hauge: "[Expeditions to high altitudes--what can we learn from them?]." in: Tidsskrift for den Norske lægeforening : tidsskrift for praktisk medicin, ny række, Vol. 111, Issue 8, pp. 926-8, 1991

Images

Product Details anti-FGFR1 Antibody Target Details FGFR1 Application Details Handling References for anti-FGFR1 antibody (ABIN1882081) back to top
Supplier Images
Flow Cytometry (FACS) image for anti-Fibroblast Growth Factor Receptor 1 (FGFR1) (AA 19-48), (N-Term) antibody (ABIN1882081) The anti-FGFR1 Pab (ABIN1882081) is used in Western blot to detect FGFR1 in NIH-3T3 c...
Immunohistochemistry (IHC) image for anti-Fibroblast Growth Factor Receptor 1 (FGFR1) (AA 19-48), (N-Term) antibody (ABIN1882081) The anti-FGFR1 Pab (ABIN1882081) is used in Western blot to detect FGFR1 in NIH-3T3 c...
Western Blotting (WB) image for anti-Fibroblast Growth Factor Receptor 1 (FGFR1) (AA 19-48), (N-Term) antibody (ABIN1882081) The anti-FGFR1 Pab (ABIN1882081) is used in Western blot to detect FGFR1 in NIH-3T3 c...
Immunofluorescence (IF) image for anti-Fibroblast Growth Factor Receptor 1 (FGFR1) (AA 19-48), (N-Term) antibody (ABIN1882081) The anti-FGFR1 Pab (ABIN1882081) is used in Western blot to detect FGFR1 in NIH-3T3 c...