Mouse anti-Human IgE Antibody
WB, EIA
Monoclonal
1A2
IgG1
unconjugated
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- Target See all IgE products
- IgE
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Application
- Western Blotting (WB), Enzyme Immunoassay (EIA)
- Cross-Reactivity (Details)
- Species reactivity (tested):Human.
- Purification
- Protein A Chromatography
- Clone
- 1A2
- Isotype
- IgG1
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Mouse anti-Human IgE (Fc Region) antibody
ELISA, WB, FACS, Func Monoclonal Le27-NBS01 IgG1 kappa unconjugated
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Restrictions
- For Research Use only
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- Concentration
- 1.0 mg/mL
- Buffer
- PBS containing 0.01 % Thimerosal as a preservative.
- Preservative
- Thimerosal (Merthiolate)
- Precaution of Use
- Biohazard Informations: This product contains thimerosal which is hazardous.
- Handling Advice
- Monoclonal antibodies should not be stored at a temperature below -25 °C due to the aggregation effect of the protein.
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- Target
- IgE
- Abstract
- IgE Products
- Background
- Immunoglobulin E (IgE) is a 180 kDa soluble protein serving as an antigen-specific unit of mast cell effector mechanisms. IgE has the lowest serum concentration of all immunoglobulins (approximately 0.5 mg/l) in healthy individuals, but upon allergen challenge its concentration in blood increases dramatically. Although biological survival of free IgE is very short (T1/2 = 2 days), it is stabilized after binding to its high affinity receptor. Unlike IgM- IgG- and IgA-committed B cells, IgE-switched B cells do not undergo clonal expansion.Synonyms: Immunoglobulin E human
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