Goat anti-Human IgG Antibody

Catalog No. ABIN2690353

Product Details

Target: IgG

Reactivity: Human

Host: Goat

Clonality: Polyclonal

Application: ELISA, Western Blotting (WB), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: Purified by Protein A.

Isotype: IgG

Application Details

Application Notes: WB 1:500-2000
ELISA 1:500-2000
IHC-P 1:500-2000
IHC-F 1:500-2000

Restrictions: For Research Use only

Handling

Format: Lyophilized

Storage: -20 °C

Storage Comment: Store at -20°C

Expiry Date: 12 months

References

Wang, Li, Wang, Rong, Pang, Xu, Dong, Xiao, Wang: "Polyethylenimine-interlayered core-shell-satellite 3D magnetic microspheres as versatile SERS substrates." in: Nanoscale, Vol. 7, Issue 44, pp. 18694-707, (2015) (PubMed).

Zhang, Huang, Lu, Liu, Li, Zhang, Yao et al.: "A double signal electrochemical human immunoglobulin G immunosensor based on gold nanoparticles-polydopamine functionalized reduced graphene oxide as a sensor platform and AgNPs/carbon nanocomposite ..." in: Biosensors & bioelectronics, Vol. 77, pp. 1078-85, (2015) (PubMed).

Gao, Li, Ma, Zhang: "An amphioxus gC1q protein binds human IgG and initiates the classical pathway: Implications for a C1q-mediated complement system in the basal chordate." in: European journal of immunology, Vol. 44, Issue 12, pp. 3680-95, (2014) (PubMed).

Zhang, Wang, Song, Yang, Sadaf, Cui: "Immunoassays based on surface-enhanced fluorescence using gap-plasmon-tunable Ag bilayer nanoparticle films." in: Journal of fluorescence, Vol. 23, Issue 1, pp. 71-7, (2013) (PubMed).

Zhang, Wang, Song, Yang, Cui: "A straightforward immunoassay applicable to a wide range of antibodies based on surface enhanced fluorescence." in: Journal of fluorescence, Vol. 23, Issue 3, pp. 551-9, (2013) (PubMed).

Dong, Lin, Deng, Di: "Ultrathin gold-shell coated silver nanoparticles onto a glass platform for improvement of plasmonic sensors." in: ACS applied materials & interfaces, Vol. 5, Issue 7, pp. 2392-9, (2013) (PubMed).

Wu, Wang, Zong, Huang, Zhang, Cui: "A SERS-based immunoassay with highly increased sensitivity using gold/silver core-shell nanorods." in: Biosensors & bioelectronics, Vol. 38, Issue 1, pp. 94-9, (2012) (PubMed).

Wang, Wang, Zhang, Zhou, Siva, Song: "A C1q domain containing protein from scallop Chlamys farreri serving as pattern recognition receptor with heat-aggregated IgG binding activity." in: PLoS ONE, Vol. 7, Issue 8, pp. e43289, (2012) (PubMed).

Target Details

Target: IgG

Abstract: IgG Products

Target Type: Antibody

Background:

Immunoglobulin G (IgG), is one of the most abundant proteins in serum with normal levels between 8-17 mg/mL in adult blood. IgG is important for our defence against microorganisms and the molecules are produced by B lymphocytes as a part of our adaptive immune response. The IgG molecule has two separate functions, to bind to the pathogen that elicited the response and to recruit other cells and molecules to destroy the antigen. The variability of the IgG pool is generated by somatic recombination and the number of specificities in an individual at a given time point is estimated to be 1011 variants.