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Spt6 Products

(Suppressor of Ty 6 Homolog (SUPT6H))

Categories

Acts to stimulate transcriptional elongation by RNA polymerase II (By similarity).

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Featured Spt6 Categories

Spt6 Antibodies

High quality antibodies with extensive validation data.

Recommended Spt6 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IP, IF
Validations
  • (3)
Cat. No. ABIN7270645
Quantity 100 μL
Datasheet Datasheet

Application WB, IHC
Validations
  • (3)
Cat. No. ABIN2780483
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application IF
Validations
  • (1)
Cat. No. ABIN7259156
Quantity 200 μL
Datasheet Datasheet

Recommended Spt6 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6229273
Quantity 96 tests
Datasheet Datasheet

Recommended Spt6 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7415305
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our Spt6 products

Nojima, Tellier, Foxwell, Ribeiro de Almeida, Tan-Wong, Dhir, Dujardin, Dhir, Murphy, Proudfoot: "Deregulated Expression of Mammalian lncRNA through Loss of SPT6 Induces R-Loop Formation, Replication Stress, and Cellular Senescence." in: Molecular cell, Vol. 72, Issue 6, pp. 970-984.e7, (2019) (PubMed).

Baluapuri, Hofstetter, Dudvarski Stankovic, Endres, Bhandare, Vos, Adhikari, Schwarz, Narain, Vogt, Wang, Düster, Jung, Vanselow, Wiegering, Geyer, Maric, Gallant, Walz, Schlosser, Cramer, Eilers et al.: "MYC Recruits SPT5 to RNA Polymerase II to Promote Processive Transcription Elongation. ..." in: Molecular cell, Vol. 74, Issue 4, pp. 674-687.e11, (2019) (PubMed).

Nojima, Rebelo, Gomes, Grosso, Proudfoot, Carmo-Fonseca: "RNA Polymerase II Phosphorylated on CTD Serine 5 Interacts with the Spliceosome during Co-transcriptional Splicing." in: Molecular cell, Vol. 72, Issue 2, pp. 369-379.e4, (2018) (PubMed).

Wang, Juan, Ko, Tsai, Zare, DellOrso, Sartorelli: "The Elongation Factor Spt6 Maintains ESC Pluripotency by Controlling Super-Enhancers and Counteracting Polycomb Proteins." in: Molecular cell, Vol. 68, Issue 2, pp. 398-413.e6, (2017) (PubMed).

Wang, Zare, Mousavi, Wang, Moravec, Sirotkin, Ge, Gutierrez-Cruz, Sartorelli: "The histone chaperone Spt6 coordinates histone H3K27 demethylation and myogenesis." in: The EMBO journal, Vol. 32, Issue 8, pp. 1075-86, (2013) (PubMed).

Cygnar, Hagemeier, Kronemann, Bresnahan: "The cellular protein SPT6 is required for efficient replication of human cytomegalovirus." in: Journal of virology, Vol. 86, Issue 4, pp. 2011-20, (2012) (PubMed).

Chen, Ma, Wu, Xiong, Ma, Xu, Lv, Li, Villen, Gygi, Liu, Shi: "The histone H3 Lys 27 demethylase JMJD3 regulates gene expression by impacting transcriptional elongation." in: Genes & development, Vol. 26, Issue 12, pp. 1364-75, (2012) (PubMed).

Willmann, Milosevic, Pauklin, Schmitz, Rangam, Simon, Maslen, Skehel, Robert, Heyer, Schiavo, Reina-San-Martin, Petersen-Mahrt: "A role for the RNA pol II-associated PAF complex in AID-induced immune diversification." in: The Journal of experimental medicine, Vol. 209, Issue 11, pp. 2099-111, (2012) (PubMed).

Kronemann, Hagemeier, Cygnar, Phillips, Bresnahan: "Binding of the human cytomegalovirus (HCMV) tegument protein UL69 to UAP56/URH49 is not required for efficient replication of HCMV." in: Journal of virology, Vol. 84, Issue 18, pp. 9649-54, (2010) (PubMed).

Synonyms and alternative names related to Spt6

SPT6 homolog, histone chaperone (SUPT6H), suppressor of Ty 6 (Supt6), SPT6 homolog, histone chaperone (Supt6h), SPT6 homolog, histone chaperone (supt6h), SUPT6H,-like protein to suppressor of ty 6 (SUPT6H), transcription elongation factor SPT6 (LOC100092175), suppressor of Ty 6 homolog (S. cerevisiae) (SUPT6H), chromatin-remodeling histone chaperone (SPT6), 5131400N11Rik, AI132449, emb-5, MGC146884, mKIAA0162, SPT6, Spt6, spt6, SPT6H, spt6h, Supt6h, SUPT6H, wu:fj42h11

Protein level used designations for Spt6

  • hSPT6
  • tat-CT2 protein
  • tat-cotransactivator 2 protein
  • transcription elongation factor SPT6
  • suppressor of Ty 6 homolog
  • pan
  • pandora
  • protein pandora
  • suppressor of Ty 6 homolog (S. cerevisiae)
  • Spt6 gene product
  • SUPT6H,-like protein to suppressor of ty 6
  • transcription elongation factor SPT6-like
  • hypothetical protein
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