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SPTBN1 Products

(Spectrin Beta, Non-Erythrocytic 1 (SPTBN1))

Categories

Spectrin is an actin crosslinking and molecular scaffold protein that links the plasma membrane to the actin cytoskeleton, and functions in the determination of cell shape, arrangement of transmembrane proteins, and organization of organelles. It is composed of two antiparallel dimers of alpha- and beta- subunits. This gene is one member of a family of beta-spectrin genes. The encoded protein contains an N-terminal actin-binding domain, and 17 spectrin repeats which are involved in dimer formation. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].

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Featured SPTBN1 Categories

SPTBN1 Antibodies

High quality antibodies with extensive validation data.

Recommended SPTBN1 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application ELISA, IHC, IF
Validations
  • (3)
Cat. No. ABIN7170440
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA, IF, ICC
Validations
  • (2)
Cat. No. ABIN6265268
Quantity 100 μL
Datasheet Datasheet
Reactivity Mouse
Application WB
Validations
  • (1)
Cat. No. ABIN6244059
Quantity 50 μL
Datasheet Datasheet

Recommended SPTBN1 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6233402
Quantity 96 tests
Datasheet Datasheet

Latest Publications for our SPTBN1 products

Lin, Yao, Bhuvaneshwar, Gusev, Kallakury, Yang, Shetty, He: "Transcriptional regulation of STAT3 by SPTBN1 and SMAD3 in HCC through cAMP-response element-binding proteins ATF3 and CREB2." in: Carcinogenesis, Vol. 35, Issue 11, pp. 2393-403, (2014) (PubMed).

Salcedo-Sicilia, Granell, Jovic, Sicart, Mato, Johannes, Balla, Egea: "βIII spectrin regulates the structural integrity and the secretory protein transport of the Golgi complex." in: The Journal of biological chemistry, Vol. 288, Issue 4, pp. 2157-66, (2013) (PubMed).

Dai, Lidie, Chen, Adelsberger, Zheng, Huang, Yang, Lempicki, Rehman, Dewar, Wang, Hornung, Canizales, Lockett, Lane, Imamichi: "IL-27 inhibits HIV-1 infection in human macrophages by down-regulating host factor SPTBN1 during monocyte to macrophage differentiation." in: The Journal of experimental medicine, Vol. 210, Issue 3, pp. 517-34, (2013) (PubMed).

Nicolas, Fournier, Galand, Malbert-Colas, Bournier, Kroviarski, Bourgeois, Camonis, Dhermy, Grandchamp, Lecomte: "Tyrosine phosphorylation regulates alpha II spectrin cleavage by calpain." in: Molecular and cellular biology, Vol. 22, Issue 10, pp. 3527-36, (2002) (PubMed).

Hu, Watanabe, Bennett: "Characterization of human brain cDNA encoding the general isoform of beta-spectrin." in: The Journal of biological chemistry, Vol. 267, Issue 26, pp. 18715-22, (1992) (PubMed).

Moon, McMahon: "Generation of diversity in nonerythroid spectrins. Multiple polypeptides are predicted by sequence analysis of cDNAs encompassing the coding region of human nonerythroid alpha-spectrin." in: The Journal of biological chemistry, Vol. 265, Issue 8, pp. 4427-33, (1990) (PubMed).

Synonyms and alternative names related to SPTBN1

spectrin beta, non-erythrocytic 1 (Sptbn1), spectrin beta, non-erythrocytic 1 (SPTBN1), spectrin, beta, non-erythrocytic 1 (Sptbn1), 9930031C03Rik, AL033301, betaSpII, ELF, elf1, elf3, mKIAA4049, Spnb-2, Spnb1, Spnb2, SPTB2

Protein level used designations for SPTBN1

  • beta fodrin
  • beta-II spectrin
  • beta-spectrin 2, non-erythrocytic
  • brain spectrin
  • embryonic liver fodrin
  • fodrin beta chain
  • non-erythrocytic
  • spectrin G
  • spectrin beta 2
  • spectrin beta chain, brain 1
  • spectrin beta chain, non-erythrocytic 1
  • spectrin, non-erythroid beta chain 1
  • beta-G spectrin
  • beta-fodrin
  • beta-spectrin 2
  • beta-spectrin II
  • beta-spectrin non-erythrocytic 1
  • embryonic liver beta-fodrin
  • bSPII-
  • beta II spectrin-like (short form)
  • cytoskeleton protein
  • non-erythroid spectrin beta
  • short form of beta II spectrin
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