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anti-Human FZD7 Antibodies:
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Cow (Bovine) Polyclonal FZD7 Primary Antibody for IHC, WB - ABIN2776708
Vincan, Darcy, Smyth, Thompson, Thomas, Phillips, Ramsay: Frizzled-7 receptor ectodomain expression in a colon cancer cell line induces morphological change and attenuates tumor growth. in Differentiation; research in biological diversity 2005
Show all 6 Pubmed References
Human Monoclonal FZD7 Primary Antibody for CyTOF, FACS - ABIN4900224
Wu, Seita, Zhang, Lu, Roth: Antibody-directed lentiviral gene transduction for live-cell monitoring and selection of human iPS and hES cells. in PLoS ONE 2012
Show all 3 Pubmed References
Human Monoclonal FZD7 Primary Antibody for CyTOF, FACS - ABIN4900225
Vijayaragavan, Szabo, Bossé, Ramos-Mejia, Moon, Bhatia: Noncanonical Wnt signaling orchestrates early developmental events toward hematopoietic cell fate from human embryonic stem cells. in Cell stem cell 2009
Show all 3 Pubmed References
Bat Polyclonal FZD7 Primary Antibody for IHC (p) - ABIN4312615
Metsuyanim, Harari-Steinberg, Buzhor, Omer, Pode-Shakked, Ben-Hur, Halperin, Schneider, Dekel: Expression of stem cell markers in the human fetal kidney. in PLoS ONE 2009
Human Polyclonal FZD7 Primary Antibody for ELISA, WB - ABIN408661
Vincan, Darcy, Farrelly, Faux, Brabletz, Ramsay: Frizzled-7 dictates three-dimensional organization of colorectal cancer cell carcinoids. in Oncogene 2007
Human Polyclonal FZD7 Primary Antibody for IF (p), IHC (p) - ABIN710051
Deng, Zhang, Zhang, Wen, Miao, Guo: MicroRNA-142-3p inhibits cell proliferation and invasion of cervical cancer cells by targeting FZD7. in Tumour biology 2015
Chimpanzee FZD7 and cow Fzd7 genes were identified and characterized.
FZD7 and IDH1 (show IDH1 Antibodies) were assessed by immunohistochemistry in tissue microarrays.
FZD7 transmits non-canonical Wnt (show WNT2 Antibodies) signaling by interacting Wnt5A (show WNT5A Antibodies) in the regulation of extracellular matrix expression.
RSPO2 (show RSPO2 Antibodies) suppresses colorectal cancer metastasis by counteracting the Wnt5a (show WNT5A Antibodies)/Fzd7-driven noncanonical Wnt (show WNT2 Antibodies) pathway.
Silencing of FZD7 inhibits the growth, migration and invasion of esophageal squamous cell carcinoma cells. Silencing of FZD7 impedes the activation of Wnt (show WNT2 Antibodies) signaling.
Taken together, our study suggests that miR (show MLXIP Antibodies)-542-3p inhibits HCC (show FAM126A Antibodies) cell growth by targeting FZD7 and inhibiting Wnt (show WNT2 Antibodies) signaling pathway. The decreased miR (show MLXIP Antibodies)-542-3p expression may also contribute to the progression of HCC (show FAM126A Antibodies) and may represent a novel molecular therapeutic target for HCC (show FAM126A Antibodies).
Findings suggest that FZD7, involved in canonical Wnt signaling pathway, plays a critical role in mediating BMSCs-dependent protection of CML cells.
Results found that FZD7 was highly upregulated by H. pylori infection and was associated with H. pylori infection-induced cell proliferation.
This paper suggests that Fzd7 may act as one of the molecules that take part in the course of renal cell carcinoma (show MOK Antibodies) formation
FZD7 is a unique and nonredundant target of NOTCH3 (show NOTCH3 Antibodies) in human breast epithelial cells.
SNX27 inhibits the Wnt regulated transcription activity of TCF/LEF. Our results suggested that SNX27 interacts with Frizzled receptors to regulate the endocytosis and stability of Fzds
cysteine-rich domain of sFRP2 (show SFRP2 Antibodies) is sufficient for Ror2 (show ROR2 Antibodies) activation, and related sFRPs can substitute for this function. Notably, direct interaction of the two receptors via their cysteine-rich domains also promotes Ror2 (show ROR2 Antibodies)-mediated papc (show PCDH8 Antibodies) expression but inhibits Fz7 signaling.
in the foregut Fzd7 signals via both the Wnt (show WNT2 Antibodies)/beta-catenin (show CTNNB1 Antibodies) and Wnt (show WNT2 Antibodies)/JNK (show MAPK8 Antibodies) pathways and different thresholds of Wnt11, 5 and 8-Fzd7 activity coordinate progenitor cell fate, proliferation and morphogenesis
Because paraxial protocadherin and C-cadherin do not directly interact nor form a joint complex with Fz7, Wnt-11 triggers the formation of two distinct complexes that act in parallel to reduce cell adhesion by hampering clustering of C-cadherin.
We therefore demonstrate that Xfz7 is regulated by BMP antagonism and is required for neural crest induction by Wnt (show WNT2 Antibodies) in the developing vertebrate embryo.
Wnt11-induced polarized accumulation of Frizzled7 and Dishevelled (show DVL2 Antibodies) at adherens junctions underlies the formation and maintenance of apicobasal cell polarity.
Results suggest that Ryk (show RYK Antibodies) functions as an essential regulator for noncanonical Wnt11/frizzled 7-mediated endocytosis in the regulation of Xenopus laevis convergent extension movements.
Fzd7 expressed by endothelial cells drives postnatal angiogenesis via activation of Dvl (show DVL1 Antibodies)/beta-catenin (show CTNNB1 Antibodies) signaling and can control the integrative interaction of Wnt (show WNT2 Antibodies) and Notch (show NOTCH1 Antibodies) signaling during postnatal angiogenesis.
Fzd7 is enriched in Lgr5 (show LGR5 Antibodies)(+) stem cells and binds Wnt3 (show WNT3 Antibodies) and Wnt2b (show WNT2B Antibodies).
the Wnt receptor, frizzled-7, is a downstream target of miR (show MLXIP Antibodies)-184, and delivery of miR (show MLXIP Antibodies)-184 mimic inhibits Wnt (show WNT2 Antibodies) signaling in the OIR retina.
Fzd7 is a new partner of adherens junctional complex and represents a novel molecular switch for the control of vascular permeabilityvia activation of the Wnt (show WNT2 Antibodies)-canonical pathway
observed genetic interactions between Fz2 (show FZD2 Antibodies) and Fz7 and five canonical and/or non-canonical signaling molecules: Dvl3 (show DVL3 Antibodies), Wnt3a (show WNT3A Antibodies), Wnt11 (show WNT11 Antibodies), Vangl2 (show VANGL2 Antibodies), and Wnt5a (show WNT5A Antibodies)
Data show that the Fzd7 receptor complex was associated with Galpha (show SUCLG1 Antibodies)(s) and PI(3 (show PI3 Antibodies))K and these components were required for Wnt7a (show WNT7A Antibodies) to activate the Akt (show AKT1 Antibodies)/mTOR (show FRAP1 Antibodies) growth pathway in myotubes.
Ror2 (show ROR2 Antibodies)/Fz7 receptor complex plays an important role in the Wnt5a (show WNT5A Antibodies)/Rac1/AP-1 (show JUN Antibodies) pathway by regulating the polymerization of Dvl (show DVL1 Antibodies).
Data suggest that upregulation of frizzled-7 receptors in association with activation of the canonical Wnt (show WNT2 Antibodies)/beta-catenin (show CTNNB1 Antibodies) pathway is a common molecular event in hepatocellular carcinoma.
Interprets Wnt (show WNT2 Antibodies) signals during embryonic mesoderm and neural induction.
Members of the 'frizzled' gene family encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. The FZD7 protein contains an N-terminal signal sequence, 10 cysteine residues typical of the cysteine-rich extracellular domain of Fz family members, 7 putative transmembrane domains, and an intracellular C-terminal tail with a PDZ domain-binding motif. FZD7 gene expression may downregulate APC function and enhance beta-catenin-mediated signals in poorly differentiated human esophageal carcinomas.
frizzled 7, seven transmembrane spanning receptor
, frizzled homolog 7
, frizzled 7
, Frizzled, drosophila, homolog of, 7