anti-Zebrafish (Danio rerio) BMP7 antibody for Immunohistochemistry

Recommended BMP7 Antibody (supplied by: Log in to see )

Antigen
Bone Morphogenetic Protein 7 (BMP7) Antibodies
  • bmp-7
  • bmp7
  • op-1
  • BMP7
  • zgc:153025
  • OP-1
  • OP1
  • BMP-7
  • fb83f09
  • wu:fb83f09
  • bone morphogenetic protein 7
  • bone morphogenetic protein 7, gene 1 L homeolog
  • bone morphogenetic protein 7b
  • bone morphogenetic protein 7, gene 2 L homeolog
  • bone morphogenetic protein 7a
  • BMP7
  • bmp7.1.L
  • LOC100136282
  • bmp7b
  • Bmp7
  • LOC100008826
  • bmp7.2.L
  • bmp7a
Epitope
N-Term
31
15
13
12
11
10
7
7
6
6
5
5
3
3
3
3
3
2
2
2
1
1
1
1
1
1
Reactivity
Cow (Bovine), Dog (Canine), Guinea Pig, Horse (Equine), Human, Mouse (Murine), Rabbit, Rat (Rattus), Sheep (Ovine), Zebrafish (Danio rerio)
240
82
54
9
7
5
5
4
4
2
1
1
1
Host
Rabbit
167
81
10
3
1
Clonality
Polyclonal
Conjugate
This BMP7 antibody is un-conjugated
23
13
11
6
6
6
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Application
Immunohistochemistry (IHC), Western Blotting (WB)
207
139
94
23
22
17
15
14
13
7
3
3
3
2
2
1
1
1
1
1
1
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Catalog No. ABIN2779569
$ 249.00
Plus shipping costs $45.00

General

Antigen Bone Morphogenetic Protein 7 (BMP7) Antibodies
Epitope N-Term
(31), (15), (13), (12), (11), (10), (7), (7), (6), (6), (5), (5), (3), (3), (3), (3), (3), (2), (2), (2), (1), (1), (1), (1), (1), (1)
Reactivity Cow (Bovine), Dog (Canine), Guinea Pig, Horse (Equine), Human, Mouse (Murine), Rabbit, Rat (Rattus), Sheep (Ovine), Zebrafish (Danio rerio)
(240), (82), (54), (9), (7), (5), (5), (4), (4), (2), (1), (1), (1)
Host Rabbit
(167), (81), (10), (3), (1)
Clonality
Polyclonal
Conjugate This BMP7 antibody is un-conjugated
(23), (13), (11), (6), (6), (6), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Immunohistochemistry (IHC), Western Blotting (WB)
(207), (139), (94), (23), (22), (17), (15), (14), (13), (7), (3), (3), (3), (2), (2), (1), (1), (1), (1), (1), (1)
Pubmed 9 references available
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Product Details anti-BMP7 Antibody

Target Details BMP7 Application Details Handling References for anti-BMP7 antibody (ABIN2779569) Images
Sequence QGKHNSAPMF MLDLYNAMAV EEGGGPGGQG FSYPYKAVFS TQGPPLASLQ
Predicted Reactivity Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 91%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%, Zebrafish: 82%
Characteristics This is a rabbit polyclonal antibody against BMP7. It was validated on Western Blot and immunohistochemistry.
Purification Protein A purified
Immunogen The immunogen is a synthetic peptide directed towards the N terminal region of human BMP7
Plasmids, Primers & others

Target Details BMP7

Product Details anti-BMP7 Antibody Application Details Handling References for anti-BMP7 antibody (ABIN2779569) Images back to top
Antigen
Alternative Name BMP7 (BMP7 Antibody Abstract)
Background The bone morphogenetic proteins (BMPs) are a family of secreted signaling molecules that can induce ectopic bone growth. Many BMPs are part of the transforming growth factor-beta (TGFB) superfamily. BMPs were originally identified by an ability of demineralized bone extract to induce endochondral osteogenesis in vivo in an extraskeletal site. Based on its expression early in embryogenesis, the BMP has a proposed role in early development. In addition, the fact that this BMP is closely related to BMP5 and BMP7 has lead to speculation of possible bone inductive activity.The bone morphogenetic proteins (BMPs) are a family of secreted signaling molecules that can induce ectopic bone growth. Many BMPs are part of the transforming growth factor-beta (TGFB) superfamily. BMPs were originally identified by an ability of demineralized bone extract to induce endochondral osteogenesis in vivo in an extraskeletal site. Based on its expression early in embryogenesis, the BMP encoded by this gene has a proposed role in early development. In addition, the fact that this BMP is closely related to BMP5 and BMP7 has lead to speculation of possible bone inductive activity.
Alias Symbols: OP-1
Protein Interaction Partner: NOTCH2NL, KRTAP10-3, KRTAP10-8, KRTAP10-5, KRTAP10-7, MTUS2, TRIM27, KRTAP5-9, ACTN4, BMPR2, UBC, SMAD3, SOSTDC1, CHRDL2, GDF7, BMPR1B, NOG, ACVR2B, NCOA3, BMPR1A, ENG, ACVR2A, ACVR1, SMAD1, BMP7,
Protein Size: 431
Molecular Weight 49 kDa
Gene ID 655
NCBI Accession NM_001719, NP_001710
UniProt P18075
Pathways Steroid Hormone Mediated Signaling Pathway, Stem Cell Maintenance

Application Details

Product Details anti-BMP7 Antibody Target Details BMP7 Handling References for anti-BMP7 antibody (ABIN2779569) Images back to top
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 431 AA

Restrictions For Research Use only

Handling

Product Details anti-BMP7 Antibody Target Details BMP7 Application Details References for anti-BMP7 antibody (ABIN2779569) Images back to top
Format Liquid
Concentration Lot specific
Buffer Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-BMP7 antibody (ABIN2779569)

Product Details anti-BMP7 Antibody Target Details BMP7 Application Details Handling Images back to top
Product cited in:

Whiteland, Spencer-Harty, Thomas, Davies, Morgan, Kynaston, Bose, Fenn, Lewis, Bodger, Jenkins, Doak: "Putative prognostic epithelial-to-mesenchymal transition biomarkers for aggressive prostate cancer." in: Experimental and molecular pathology, Vol. 95, Issue 2, pp. 220-6, 2013

Lovric, Chen, Yu, Oliver, Genin, Walsh: "Effects of demineralized bone matrix on tendon-bone healing in an intra-articular rodent model." in: The American journal of sports medicine, Vol. 40, Issue 10, pp. 2365-74, 2012

Rui, Lui, Rolf, Wong, Lee, Chan: "Expression of chondro-osteogenic BMPs in clinical samples of patellar tendinopathy." in: Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA, Vol. 20, Issue 7, pp. 1409-17, 2012

Fiaschetti, Castelletti, Zoller, Schramm, Schroeder, Nagaishi, Stearns, Mittelbronn, Eggert, Westermann, Ohgaki, Shalaby, Pruschy, Arcaro, Grotzer: "Bone morphogenetic protein-7 is a MYC target with prosurvival functions in childhood medulloblastoma." in: Oncogene, Vol. 30, Issue 25, pp. 2823-35, 2011

Filion, Li, Mason-Savas, Kreider, Goldstein, Ayers, Song: "Elastomeric osteoconductive synthetic scaffolds with acquired osteoinductivity expedite the repair of critical femoral defects in rats." in: Tissue engineering. Part A, Vol. 17, Issue 3-4, pp. 503-11, 2011

Mae, Shirasawa, Yoshie, Sato, Kanoh, Ichikawa, Yokoyama, Yue, Tomotsune, Sasaki: "Combination of small molecules enhances differentiation of mouse embryonic stem cells into intermediate mesoderm through BMP7-positive cells." in: Biochemical and biophysical research communications, Vol. 393, Issue 4, pp. 877-82, 2010

Yi, Tan, Cho, Wang, Luo, Zhang, Li, Liu: "Regulation of embryonic kidney branching morphogenesis and glomerular development by KISS1 receptor (Gpr54) through NFAT2- and Sp1-mediated Bmp7 expression." in: The Journal of biological chemistry, Vol. 285, Issue 23, pp. 17811-20, 2010

Morrissey, Brown, Pitts, Vessella, Corey: "Bone morphogenetic protein 7 is expressed in prostate cancer metastases and its effects on prostate tumor cells depend on cell phenotype and the tumor microenvironment." in: Neoplasia (New York, N.Y.), Vol. 12, Issue 2, pp. 192-205, 2010

Background publications

Gregory, Ono, Charbonneau, Kuo, Keene, Bächinger, Sakai: "The prodomain of BMP-7 targets the BMP-7 complex to the extracellular matrix." in: The Journal of biological chemistry, Vol. 280, Issue 30, pp. 27970-80, 2005

Images

Product Details anti-BMP7 Antibody Target Details BMP7 Application Details Handling References for anti-BMP7 antibody (ABIN2779569) back to top
Supplier Images
Immunohistochemistry (IHC) image for anti-Bone Morphogenetic Protein 7 (BMP7) (N-Term) antibody (ABIN2779569) Human kidney
Western Blotting (WB) image for anti-Bone Morphogenetic Protein 7 (BMP7) (N-Term) antibody (ABIN2779569) WB Suggested Anti-BMP7 Antibody Titration: 1.25ug/ml ELISA Titer: 1:1562500 Posit...
Western Blotting (WB) image for anti-Bone Morphogenetic Protein 7 (BMP7) (N-Term) antibody (ABIN2779569) Host: Rabbit Target Name: BMP7 Sample Tissue: Human NCI-H226 Antibody Dilution:...
Western Blotting (WB) image for anti-Bone Morphogenetic Protein 7 (BMP7) (N-Term) antibody (ABIN2779569) Host: Rabbit Target Name: BMP7 Sample Type: Human Thyroid Antibody Dilution: 1...