anti-Ferret CD8 antibody for Immunohistochemistry (Paraffin-embedded Sections)

Recommended CD8 Antibody (supplied by: Log in to see )

Antigen
CD8a Molecule (CD8A) Antibodies
  • cd8
  • LOC100136450
  • BB154331
  • Ly-2
  • Ly-35
  • Ly-B
  • Lyt-2
  • zgc:136643
  • CD8
  • Leu2
  • MAL
  • p32
  • RHACD8-4
  • CD8a molecule
  • uncharacterized LOC100125537
  • CD8 alpha
  • CD8 antigen, alpha chain
  • T-cell surface glycoprotein CD8 alpha chain
  • Cd8a
  • LOC100125537
  • LOC100136450
  • CD8A
  • cd8a
  • LOC100126556
Epitope
AA 1-186
81
26
19
17
15
12
12
12
12
11
11
9
9
8
7
7
6
5
4
3
3
3
2
2
2
2
1
1
1
1
1
1
1
1
Reactivity
Ferret
614
479
147
91
47
24
15
15
15
12
12
9
6
4
2
2
2
2
2
2
2
1
1
Host
Rabbit
729
428
266
1
Clonality
Polyclonal
Conjugate
This CD8 antibody is un-conjugated
152
147
89
88
37
33
32
26
23
22
21
19
18
17
17
17
17
17
16
15
14
14
12
12
11
10
8
8
7
6
5
5
4
4
4
4
3
3
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), ELISA
1166
444
294
254
249
217
210
154
146
29
20
20
18
14
13
11
10
6
6
5
4
4
2
2
2
2
2
1
1
1
1
1
1
1
Options
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Available images

Catalog No. ABIN2001461
$ 352.65
Plus shipping costs $45.00

General

Antigen CD8a Molecule (CD8A) Antibodies
Epitope AA 1-186
(81), (26), (19), (17), (15), (12), (12), (12), (12), (11), (11), (9), (9), (8), (7), (7), (6), (5), (4), (3), (3), (3), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Ferret
(614), (479), (147), (91), (47), (24), (15), (15), (15), (12), (12), (9), (6), (4), (2), (2), (2), (2), (2), (2), (2), (1), (1)
Host Rabbit
(729), (428), (266), (1)
Clonality
Polyclonal
Conjugate This CD8 antibody is un-conjugated
(152), (147), (89), (88), (37), (33), (32), (26), (23), (22), (21), (19), (18), (17), (17), (17), (17), (17), (16), (15), (14), (14), (12), (12), (11), (10), (8), (8), (7), (6), (5), (5), (4), (4), (4), (4), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), ELISA
(1166), (444), (294), (254), (249), (217), (210), (154), (146), (29), (20), (20), (18), (14), (13), (11), (10), (6), (6), (5), (4), (4), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1)
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Product Details anti-CD8 Antibody

Target Details CD8 Application Details Handling Images
Specificity Ferret CD8a
Characteristics Produced in rabbits immunized with purified, recombinant Ferret CD8a (rF CD8a, ABIN2008785 ABS50091.1, Met 1-Glu 186,. CD8a specific IgG was purified by Ferret CD8a affinity chromatography.
Purification purified by affinity chromatography
Sterility 0.2 μm filtered
Immunogen Recombinant Ferret CD8a protein (ABIN2008785)
Isotype IgG
Plasmids, Primers & others

Target Details CD8

Product Details anti-CD8 Antibody Application Details Handling Images back to top
Antigen
Alternative Name CD8A (CD8A Antibody Abstract)
Background T-cell surface glycoprotein CD8 alpha chain, also known as CD8a, is a single-pass type I membrane protein. The CD8 glycoprotein is expressed by thymocytes, mature T cells and natural killer (NK) cells and has been implicated in the recognition of monomorphic determinants on major histocompatibility complex (MHC) Class I antigens, and in signal transduction during the course of T-cell activation. Both human and rodent CD8 antigens are comprised of two distinct polypeptide chains, alpha and beta. The Ig domains of CD8 alpha are involved in controlling the ability of CD8 to be expressed. Mutation of B- and F- strand cysteine residues in CD8 alpha reduced the ability of the protein to fold properly and, therefore, to be expressed. Defects in CD8A are a cause of familial CD8 deficiency. Familial CD8 deficiency is a novel autosomal recessive immunologic defect characterized by absence of CD8+ cells, leading to recurrent bacterial infections.
UniProt ABS50091.1
Pathways TCR Signaling

Application Details

Product Details anti-CD8 Antibody Target Details CD8 Handling Images back to top
Application Notes ELISA: 0.1-0.2 μg/mL
This antibody can be used at 0.1-0.2 μg/mL with the appropriate secondary reagents to detect Ferret CD8A. The detection limit for Ferret CD8A is approximately 0.00975 ng/well.
IHC-P: 0.1-2 μg/mL
Restrictions For Research Use only

Handling

Product Details anti-CD8 Antibody Target Details CD8 Application Details Images back to top
Format Liquid
Buffer 0.2 μm filtered solution in PBS with 5 % trehalose
Preservative Without preservative
Handling Advice Avoid repeated freeze-thaw cycles.
Storage 4 °C,-20 °C,-80 °C
Storage Comment This antibody can be stored at 2°C-8°C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20°C to -80°C. Preservative-Free.
Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.
Expiry Date 12 months

Images

Product Details anti-CD8 Antibody Target Details CD8 Application Details Handling back to top
Supplier Images
Immunohistochemistry (IHC) image for anti-CD8a Molecule (CD8A) (AA 1-186) antibody (ABIN2001461) Immunochemical staining of ferret CD8A in ferret spleen with rabbit polyclonal antibo...