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Browse our anti-Primase, DNA, Polypeptide 1 (49kDa) (PRIM1) Antibodies

Full name:: anti-Primase, DNA, Polypeptide 1 (49kDa) Antibodies (PRIM1)

On www.antibodies-online.com are 47 Primase, DNA, Polypeptide 1 (49kDa) (PRIM1) Antibodies from 17 different suppliers available. Additionally we are shipping Primase, DNA, Polypeptide 1 (49kDa) Proteins (5) and and many more products for this protein. A total of 60 Primase, DNA, Polypeptide 1 (49kDa) products are currently listed.

Synonyms:: AI324982, dnapol-alpha50, p49

list all antibodies	Gene Name	GeneID	UniProt
	PRIM1	19075	P20664
	PRIM1	246327
	PRIM1	5557	P49642
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Most Popular Reactivities for anti-Primase, DNA, Polypeptide 1 (49kDa) (PRIM1) Antibodies

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anti-Mouse (Murine) Antibodies:

29 WB Antibodies

anti-Rat (Rattus) Antibodies:

21 WB Antibodies

anti-Human Antibodies:

All available anti-Primase, DNA, Polypeptide 1 (49kDa) Antibodies

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More Antibodies against Primase, DNA, Polypeptide 1 (49kDa) Interaction Partners

Human Primase, DNA, Polypeptide 1 (49kDa) (PRIM1) interaction partners

the structure of human p49at 2.2A resolution with citrate in its inactive forms, is reported.
PRIM1 was detected preferentially at a higher level (>40-fold) in poorly differentiated tumor tissues (n = 46) compared with more highly differentiated tumors tissues (n = 10) (*p = 0.005).
PRIM1 inactivation sensitizes cancer cells to ATR and CHK1 inhibitors via S-phase stasis and Wee1-mediated, caspase 8-dependent apoptosis.
No mutations within PRIM1 were found in Chinese women with primary ovarian insufficiency.
Data suggest that PRIM1-p58,C-terminal domain stays bound to initiating NTP and 3prime-overhang DNA during whole cycle of RNA primer synthesis; meanwhile, PRIM1-p49 slides along DNA template toward 5prime-end with PRIM1-p58,N-terminal domain attached.
Data indicate that the conformational changes in primase are necessary to accomplish the initiation and then elongation of RNA synthesis.
Findings indicate that tethering of DNA primase Prim1 to the replisome by DNA polymerase alpha (pol alpha) is critical for the normal action of DNA replication forks in eukaryotic cells.
Mechanisms by which human DNA primase chooses to polymerize a nucleoside triphosphate

Primase, DNA, Polypeptide 1 (49kDa) (PRIM1) Antigen Profile

Antigen Summary

The replication of DNA in eukaryotic cells is carried out by a complex chromosomal replication apparatus, in which DNA polymerase alpha and primase are two key enzymatic components. Primase, which is a heterodimer of a small subunit and a large subunit, synthesizes small RNA primers for the Okazaki fragments made during discontinuous DNA replication. The protein encoded by this gene is the small, 49 kDa primase subunit.

Alternative names and synonyms associated with Primase, DNA, Polypeptide 1 (49kDa) (PRIM1)

DNA primase, p49 subunit (Prim1) antibody
DNA primase subunit 1 (Prim1) antibody
DNA primase subunit 1 (PRIM1) antibody
DNA primase subunit 1 S homeolog (prim1.S) antibody

AI324982 antibody
dnapol-alpha50 antibody
p49 antibody

Protein level used designations for PRIM1

DNA primase 49 kDa subunit , DNA primase small subunit , p49 , DNA primase small subunit, 49kDa , DNA primase, p49 subunit , DNA primase 1 , DNA primase subunit 48 , primase p49 subunit , primase polypeptide 1, 49kDa , primase, polypeptide 1, 49kDa

GENE ID	SPECIES
19075	Mus musculus
246327	Rattus norvegicus
5557	Homo sapiens
380513	Xenopus laevis
506240	Bos taurus

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