anti-Human TLR1 antibody for Immunohistochemistry

Recommended TLR1 Antibody (supplied by: Log in to see )

Antigen
Toll-Like Receptor 1 (TLR1) Antibodies
  • CD281
  • TIL
  • TIL. LPRS5
  • rsc786
  • toll like receptor 1
  • toll-like receptor 1
  • TLR1
  • Tlr1
Reactivity
Mouse (Murine), Rat (Rattus), Human
178
90
41
1
Host
Rabbit
140
47
17
1
Clonality
Polyclonal
Conjugate
This TLR1 antibody is un-conjugated
18
17
16
5
5
3
1
1
1
1
1
1
1
1
1
1
1
1
Application
Immunohistochemistry (IHC), Western Blotting (WB)
131
78
74
52
37
14
14
13
13
12
11
7
6
3
2
Options
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Catalog No. ABIN3023655
$ 393.25
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
21.992594 ABIN5693146 ELISA FACS ICC IHC WB Rabbit AA 350-404 Log in to see Polyclonal 0
18.753246 ABIN3181539 IHC Rabbit IgG Log in to see Polyclonal 0
18.753246 ABIN3181537 IHC Rabbit IgG Log in to see Polyclonal 0
12.992594 ABIN2427609 IHC ELISA WB Rabbit IgG Log in to see Polyclonal 0
10 ABIN6002117 IF/ICC IHC IP WB Mouse AA 114-339 Log in to see 0
10 ABIN5662353 IHC WB Mouse AA 114-339 Log in to see 0
9.992594 ABIN959418 FACS IHC IHC (p) WB Rabbit IgG AA 400-450 Log in to see Polyclonal 0
9.992594 ABIN6265596 ELISA IHC WB Rabbit IgG Log in to see Polyclonal 0
9.992594 ABIN213996 ICC IHC IHC (p) WB Rabbit IgG Internal Region Log in to see Polyclonal 0
9.992594 ABIN214527 IHC IHC (p) WB Rabbit IgG N-Term Log in to see Polyclonal 0
9.992594 ABIN1031619 IHC ELISA WB Rabbit N-Term Log in to see Polyclonal 0
9.992594 ABIN3029159 IHC ELISA WB Rabbit Ig Fraction AA 764-795 Log in to see Polyclonal 0
7 ABIN1875107 IF IHC WB Rabbit IgG Log in to see Polyclonal 0
7 ABIN1860768 ICC IHC WB Rabbit IgG AA 605-785 Log in to see Polyclonal 0
7 ABIN1175315 ICC IHC WB Rabbit IgG AA 114-339 Log in to see Polyclonal 0
7 ABIN2903124 IF/ICC IHC IP WB Rabbit AA 114-339 Log in to see Polyclonal 0
7 ABIN2903125 IF/ICC IHC IP WB Rabbit AA 605-785 Log in to see Polyclonal 0
5.5 ABIN1003315 IHC ELISA WB Rabbit IgG N-Term Log in to see Polyclonal 4
1 ABIN2888061 IF IHC WB Rabbit IgG Log in to see Polyclonal 0
1 ABIN2893979 IHC WB Rabbit Log in to see Polyclonal 0

General

Antigen Toll-Like Receptor 1 (TLR1) Antibodies
Reactivity Mouse (Murine), Rat (Rattus), Human
(178), (90), (41), (1)
Host Rabbit
(140), (47), (17), (1)
Clonality
Polyclonal
Conjugate This TLR1 antibody is un-conjugated
(18), (17), (16), (5), (5), (3), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Immunohistochemistry (IHC), Western Blotting (WB)
(131), (78), (74), (52), (37), (14), (14), (13), (13), (12), (11), (7), (6), (3), (2)
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Product Details anti-TLR1 Antibody

Target Details TLR1 Application Details Handling Images
Purification Affinity purification
Immunogen Recombinant protein of human TLR1
Isotype IgG
Plasmids, Primers & others

Target Details TLR1

Product Details anti-TLR1 Antibody Application Details Handling Images back to top
Antigen
Alternative Name TLR1 (TLR1 Antibody Abstract)
Background Members of the Toll-like receptor (TLR) family, named for the closely related Toll receptor in Drosophila, play a pivotal role in innate immune responses. TLRs recognize conserved motifs found in various pathogens and mediate defense responses. Triggering of the TLR pathway leads to the activation of NF-kappaB and subsequent regulation of immune and inflammatory genes. The TLRs and members of the IL-1 receptor family share a conserved stretch of approximately 200 AAs known as the TIR domain. Upon activation, TLRs associate with a number of cytoplasmic adaptor proteins containing TIR domains including MyD88 (myeloid differentiation factor), MAL/TIRAP (MyD88-adaptor-like/TIR-associated protein), TRIF (Toll-receptor-associated activator of interferon), and TRAM (Toll-receptor-associated molecule). This association leads to the recruitment and activation of IRAK1 and IRAK4, which form a complex with TRAF6 to activate TAK1 and IKK. Activation of IKK leads to the degradation of IkappaB that normally maintains NF-kappaB inactivity by sequestering it in the cytoplasm. Toll-like receptor expression is highest in peripheral blood leukocytes, monocytes, macrophages, though TLR1 expression may be less restricted than other family members. TLR1 associates with TLR2 to cooperatively mediate immune responses to bacterial lipoproteins and lead to NF-kappaB activation. TLR1 shows highest homology to TLR6, which shares 69 % sequence identity.
Synonyms: TLR1, CD281, DKFZp547I0610, DKFZp564I0682, KIAA0012, MGC104956, MGC126311, MGC126312, TIL, rsc786
Gene ID 7096
UniProt Q15399
Pathways TLR Signaling, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades

Application Details

Product Details anti-TLR1 Antibody Target Details TLR1 Handling Images back to top
Application Notes Recommended dilutions: WB: 1:500-1:2000, IHC: 1:50-1:200
Restrictions For Research Use only

Handling

Product Details anti-TLR1 Antibody Target Details TLR1 Application Details Images back to top
Format Liquid
Buffer PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid freeze / thaw cycles
Storage -20 °C/-80 °C

Images

Product Details anti-TLR1 Antibody Target Details TLR1 Application Details Handling back to top
Supplier Images
Western Blotting (WB) image for anti-Toll-Like Receptor 1 (TLR1) antibody (ABIN3023655) Western blot analysis of extracts of various cell lines, using TLR1 antibody.
Immunofluorescence (IF) image for anti-Toll-Like Receptor 1 (TLR1) antibody (ABIN3023655) Immunofluorescence analysis of HeLa cell using TLR1 antibody. Blue: DAPI for nuclear ...
Western Blotting (WB) image for anti-Toll-Like Receptor 1 (TLR1) antibody (ABIN3023655) Western blot analysis of extracts of various cell lines, using TLR1 antibody.
Immunofluorescence (IF) image for anti-Toll-Like Receptor 1 (TLR1) antibody (ABIN3023655) Immunofluorescence analysis of HeLa cells using TLR1 antibody.