anti-Human TLR10 antibody for Intracellular Flow Cytometry

Recommended TLR10 Antibody (supplied by: Log in to see )

Antigen
Toll-Like Receptor 10 (TLR10) Antibodies
  • TLR10
  • CD290
  • toll like receptor 10
  • toll-like receptor 10
  • TLR10
  • Tlr10
Epitope
AA 20-474
6
4
4
4
3
3
3
3
2
2
1
1
1
1
1
Reactivity
Human
105
10
7
3
3
3
Host
Mouse
59
49
1
Clonality
Monoclonal
Conjugate
This TLR10 antibody is conjugated to PE
4
3
2
2
2
2
2
2
2
2
2
2
2
2
2
1
Application
Intracellular Flow Cytometry (ICFC)
66
39
21
11
11
8
7
6
3
3
1
1
1
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Catalog No. ABIN2662577
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Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
1 ABIN2662578 ICFC PE Mouse IgG1 kappa AA 20-474 Log in to see 3C10C5 4

General

Antigen Toll-Like Receptor 10 (TLR10) Antibodies
Epitope AA 20-474
(6), (4), (4), (4), (3), (3), (3), (3), (2), (2), (1), (1), (1), (1), (1)
Reactivity Human
(105), (10), (7), (3), (3), (3)
Host Mouse
(59), (49), (1)
Clonality (Clone)
Monoclonal   ( )
Conjugate This TLR10 antibody is conjugated to PE
(4), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1)
Application Intracellular Flow Cytometry (ICFC)
(66), (39), (21), (11), (11), (8), (7), (6), (3), (3), (1), (1), (1)
Pubmed 4 references available
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Product Details anti-TLR10 Antibody

Target Details TLR10 Application Details Handling References for anti-TLR10 antibody (ABIN2662577) Images
Cross-Reactivity Cynomolgus
Purification The antibody was purified by affinity chromatography and conjugated with PE under optimal conditions. The solution is free of unconjugated PE and unconjugated antibody.
Immunogen AA 20-474 (NP_001017388)
Clone 3C10C5
Isotype IgG1 kappa
Plasmids, Primers & others

Target Details TLR10

Product Details anti-TLR10 Antibody Application Details Handling References for anti-TLR10 antibody (ABIN2662577) Images back to top
Antigen
Alternative Name CD290 (TLR10 Antibody Abstract)
Background CD290, also known as TLR10, is a 91-100 kD glycosylated protein belonging to the toll-like receptor family. It is expressed on B cell, Treg cells, and plasmacytoid dendritic cells but absent on T cells, particularly non-Treg and granulocytes. It can interact with MyD88 and plays an important role in innate immunity and pattern recognition.
Pathways TLR Signaling, Activation of Innate immune Response, Toll-Like Receptors Cascades

Application Details

Product Details anti-TLR10 Antibody Target Details TLR10 Handling References for anti-TLR10 antibody (ABIN2662577) Images back to top
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only

Handling

Product Details anti-TLR10 Antibody Target Details TLR10 Application Details References for anti-TLR10 antibody (ABIN2662577) Images back to top
Buffer Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and 0.2 % (w/v) BSA .
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Protect from prolonged exposure to light. Do not freeze.
Storage 4 °C
Storage Comment The antibody solution should be stored undiluted between 2°C and 8°C.

References for anti-TLR10 antibody (ABIN2662577)

Product Details anti-TLR10 Antibody Target Details TLR10 Application Details Handling Images back to top
Background publications

Guan, Ranoa, Jiang, Mutha, Li, Baudry, Tapping: "Human TLRs 10 and 1 share common mechanisms of innate immune sensing but not signaling." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 184, Issue 9, pp. 5094-103, 2010

Bourke, Bosisio, Golay, Polentarutti, Mantovani: "The toll-like receptor repertoire of human B lymphocytes: inducible and selective expression of TLR9 and TLR10 in normal and transformed cells." in: Blood, Vol. 102, Issue 3, pp. 956-63, 2003

Hornung, Rothenfusser, Britsch, Krug, Jahrsdörfer, Giese, Endres, Hartmann: "Quantitative expression of toll-like receptor 1-10 mRNA in cellular subsets of human peripheral blood mononuclear cells and sensitivity to CpG oligodeoxynucleotides." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 168, Issue 9, pp. 4531-7, 2002

Chuang, Ulevitch: "Identification of hTLR10: a novel human Toll-like receptor preferentially expressed in immune cells." in: Biochimica et biophysica acta, Vol. 1518, Issue 1-2, pp. 157-61, 2001

Images

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Supplier Images
Flow Cytometry (FACS) image for anti-Toll-Like Receptor 10 (TLR10) (AA 20-474) antibody (PE) (ABIN2662577) anti-Toll-Like Receptor 10 (TLR10) (AA 20-474) antibody (PE)
Flow Cytometry (FACS) image for anti-Toll-Like Receptor 10 (TLR10) (AA 20-474) antibody (PE) (ABIN2662577) anti-Toll-Like Receptor 10 (TLR10) (AA 20-474) antibody (PE) (Image 2)