anti-Rat (Rattus) TLR4 antibody for Immunofluorescence
Recommended TLR4 Antibody (supplied by: Log in to see )
- Antigen
-
Toll-Like Receptor 4 (TLR4) Antibodies
show synonyms for this antigen- ARMD10
- CD284
- TLR-4
- TOLL
- Lps
- Ly87
- Ran/M1
- Rasl2-8
- toll like receptor 4
- toll-like receptor 4
- TLR4
- Tlr4
- Epitope
-
pSer800
Alternatives - Reactivity
-
Human, Mouse (Murine), Rat (Rattus)
Alternatives - Host
-
Rabbit
Alternatives - Clonality
- Conjugate
-
This TLR4 antibody is un-conjugated
Alternatives - Application
-
Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blotting (WB)
Alternatives - Supplier
- Log in to see
- Supplier Product No.
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| Relevance Score | ABIN | Application | Conjugate | Host | Isotype | Epitope | Supplier | Clonality | References | Details |
|---|---|---|---|---|---|---|---|---|---|---|
| 14.5 | ABIN6269449 | ELISA ICC IF IHC WB | Rabbit | IgG | Log in to see | Polyclonal | 3 | |||
| 4 | ABIN6181202 | FACS IF IHC (f) | APC | Mouse | IgG2a, kappa | Log in to see | TLR4-230 | 0 | ||
| 4 | ABIN6181209 | FACS IF IHC (f) | PerCP | Mouse | IgG2a, kappa | Log in to see | TLR4-230 | 0 | ||
| 4 | ABIN6181210 | FACS IF IHC (f) | PE | Mouse | IgG2a, kappa | Log in to see | TLR4-230 | 0 | ||
| 4 | ABIN6181213 | FACS IF IHC (f) | Mouse | IgG2a, kappa | Log in to see | TLR4-230 | 0 | |||
| 1 | ABIN6181184 | FACS IF IHC (f) | CF®647 | Mouse | IgG2a, kappa | Log in to see | TLR4-230 | 0 | ||
| 1 | ABIN6181186 | FACS IF IHC (f) | CF®555 | Mouse | IgG2a, kappa | Log in to see | TLR4-230 | 0 | ||
| 1 | ABIN6181192 | FACS IF IHC (f) | CF®770 | Mouse | IgG2a, kappa | Log in to see | TLR4-230 | 0 | ||
| 1 | ABIN6181190 | FACS IF IHC (f) | CF®568 | Mouse | IgG2a, kappa | Log in to see | TLR4-230 | 0 | ||
| 1 | ABIN6181196 | FACS IF IHC (f) | CF®680R | Mouse | IgG2a, kappa | Log in to see | TLR4-230 | 0 | ||
| 1 | ABIN6181200 | FACS IF IHC (f) | CF®594 | Mouse | IgG2a, kappa | Log in to see | TLR4-230 | 0 | ||
| 1 | ABIN6181178 | FACS IF IHC (f) | CF405M | Mouse | IgG2a, kappa | Log in to see | TLR4-230 | 0 | ||
| 1 | ABIN6181180 | FACS IF IHC (f) | CF®640R | Mouse | IgG2a, kappa | Log in to see | TLR4-230 | 0 | ||
| 1 | ABIN6181182 | FACS IF IHC (f) | CF®543 | Mouse | IgG2a, kappa | Log in to see | TLR4-230 | 0 | ||
| 1 | ABIN6181194 | FACS IF IHC (f) | CF®680 | Mouse | IgG2a, kappa | Log in to see | TLR4-230 | 0 | ||
| 1 | ABIN6181198 | FACS IF IHC (f) | CF®488A | Mouse | IgG2a, kappa | Log in to see | TLR4-230 | 0 | ||
| 1 | ABIN6181176 | FACS IF IHC (f) | CF®405S | Mouse | IgG2a, kappa | Log in to see | TLR4-230 | 0 | ||
| 1 | ABIN6181188 | FACS IF IHC (f) | CF®660R | Mouse | IgG2a, kappa | Log in to see | TLR4-230 | 0 | ||
| 1 | ABIN6181211 | FACS IF IHC (f) | Mouse | IgG2a, kappa | Log in to see | TLR4-230 | 0 | |||
| 1 | ABIN6181203 | FACS IF IHC (f) | Alkaline Phosphatase (AP) | Mouse | IgG2a, kappa | Log in to see | TLR4-230 | 0 |
General |
|
|---|---|
| Antigen | Toll-Like Receptor 4 (TLR4) Antibodies |
| Epitope | pSer800 Alternatives |
| Reactivity | Human, Mouse (Murine), Rat (Rattus) Alternatives |
| Host | Rabbit Alternatives |
| Clonality | |
| Conjugate | This TLR4 antibody is un-conjugated Alternatives |
| Application |
Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blotting (WB)
Alternatives
|
| Supplier | Log in to see |
Product Details anti-TLR4 AntibodyTarget Details TLR4 Application Details Handling Images |
|
| Specificity | Phospho-TLR4( Ser800) Antibody detects endogenous levels of TLR4. |
| Cross-Reactivity | Human, Mouse (Murine), Rat (Rattus) |
| Purification | The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns. |
| Immunogen | A synthesized peptide derived from human TLR4 around the phosphorylation site of Ser800. |
| Isotype | IgG |
| Plasmids, Primers & others | |
Target Details TLR4Product Details anti-TLR4 Antibody Application Details Handling Images back to top |
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| Antigen | |
| Alternative Name | TLR4 (TLR4 Antibody Abstract) |
| Background |
Description: Cooperates with LY96 and CD14 to mediate the innate immune response to bacterial lipopolysaccharide (LPS) (PubMed:27022195). Acts via MYD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response (PubMed:9237759, PubMed:10835634, PubMed:27022195). Also involved in LPS-independent inflammatory responses triggered by free fatty acids, such as palmitate, and Ni2+. Responses triggered by Ni2+ require non-conserved histidines and are, therefore, species-specific (PubMed:20711192). Both M.tuberculosis HSP70 (dnaK) and HSP65 (groEL-2) act via this protein to stimulate NF-kappa-B expression (PubMed:15809303). In complex with TLR6, promotes sterile inflammation in monocytes/macrophages in response to oxidized low-density lipoprotein (oxLDL) or amyloid-beta 42. In this context, the initial signal is provided by oxLDL- or amyloid-beta 42-binding to CD36. This event induces the formation of a heterodimer of TLR4 and TLR6, which is rapidly internalized and triggers inflammatory response, leading to the NF-kappa-B-dependent production of CXCL1, CXCL2 and CCL9 cytokines, via MYD88 signaling pathway, and CCL5 cytokine, via TICAM1 signaling pathway, as well as IL1B secretion. Binds electronegative LDL (LDL-) and mediates the cytokine release induced by LDL- (PubMed:23880187). Stimulation of monocytes in vitro with M.tuberculosis PstS1 induces p38 MAPK and ERK1/2 activation primarily via TLR2, but also partially via this receptor (PubMed:16622205). Gene: TLR4 |
| Molecular Weight | 100kDa |
| Gene ID | 7099 |
| UniProt | O00206 |
| Pathways | TLR Signaling, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Toll-Like Receptors Cascades |
Application DetailsProduct Details anti-TLR4 Antibody Target Details TLR4 Handling Images back to top |
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| Application Notes | WB 1:500-1:2000 IHC 1:50-1:200 IF 1:100-1:500 |
| Restrictions | For Research Use only |
HandlingProduct Details anti-TLR4 Antibody Target Details TLR4 Application Details Images back to top |
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| Format | Liquid |
| Concentration | 1 mg/mL |
| Buffer | Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.. |
| Preservative | Sodium azide |
| Precaution of Use | This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only. |
| Storage | -20 °C |
| Storage Comment | Store at -20 °C.Stable for 12 months from date of receipt |
| Expiry Date | 12 months |
ImagesProduct Details anti-TLR4 Antibody Target Details TLR4 Application Details Handling back to top |
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| Supplier Images |
ABIN6270323 at 1/100 staining rat heart tissue sections by IHC-P. The tissue was form...
ABIN6270323 at 1/100 staining rat liver tissue sections by IHC-P. The tissue was form...
ABIN6270323 at 1/100 staining human gastric cancer tissue sections by IHC-P. The tiss...
ABIN6270323 at 1/100 staining human liver tissue sections by IHC-P. The tissue was fo...
Western blot analysis of extracts from Hela, using Phospho-TLR4(Ser800) Antibody.
ABIN6270323 staining HepG2 by IF/ICC. The sample were fixed with PFA and permeabilize...
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