anti-Human TLR7 antibody for Immunocytochemistry

Recommended TLR7 Antibody (supplied by: Log in to see )

Antigen
Toll-Like Receptor 7 (TLR7) Antibodies
  • TLR7-like
  • RGD1563357
  • toll like receptor 7
  • toll-like receptor 7
  • TLR7
  • Tlr7
Epitope
AA 1020-1047, C-Term
27
26
15
12
11
10
10
8
7
6
6
6
5
5
5
5
4
4
3
3
3
2
2
2
2
1
1
1
1
Reactivity
Human, Mouse (Murine), Rat (Rattus)
261
138
42
4
4
3
2
2
2
2
1
1
1
1
1
Host
Rabbit
196
83
2
1
Clonality
Polyclonal
Conjugate
This TLR7 antibody is un-conjugated
19
15
12
11
8
6
5
4
4
3
3
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
Application
Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
200
101
90
73
47
47
37
14
13
6
5
5
4
2
Options
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Catalog No. ABIN3043948
$ 280.00
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
7 ABIN214002 ICC IHC IHC (p) WB Rabbit IgG Log in to see Polyclonal 0
7 ABIN1860776 ICC IHC WB Rabbit IgG AA 887-1036 Log in to see Polyclonal 0
7 ABIN1031131 ICC ELISA WB Rabbit Middle Region Log in to see Polyclonal 0
5.5 ABIN1003337 ICC ELISA WB Rabbit IgG Internal Region Log in to see Polyclonal 4
4 ABIN1740125 ICC IHC (p) WB Rabbit IgG Log in to see Polyclonal 0
1 ABIN1887811 ICC ELISA WB Rabbit Middle Region Log in to see Polyclonal 0
1 ABIN4952861 ICC IHC (fro) IHC (p) WB Rabbit IgG Log in to see Polyclonal 0

General

Antigen Toll-Like Receptor 7 (TLR7) Antibodies
Epitope AA 1020-1047, C-Term
(27), (26), (15), (12), (11), (10), (10), (8), (7), (6), (6), (6), (5), (5), (5), (5), (4), (4), (3), (3), (3), (2), (2), (2), (2), (1), (1), (1), (1)
Reactivity Human, Mouse (Murine), Rat (Rattus)
(261), (138), (42), (4), (4), (3), (2), (2), (2), (2), (1), (1), (1), (1), (1)
Host Rabbit
(196), (83), (2), (1)
Clonality
Polyclonal
Conjugate This TLR7 antibody is un-conjugated
(19), (15), (12), (11), (8), (6), (5), (4), (4), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1)
Application Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(200), (101), (90), (73), (47), (47), (37), (14), (13), (6), (5), (5), (4), (2)
Pubmed 1 reference available
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Product Details anti-TLR7 Antibody

Target Details TLR7 Application Details Handling References for anti-TLR7 antibody (ABIN3043948) Images
Purpose Rabbit IgG polyclonal antibody for Toll-like receptor 7(TLR7) detection. Tested with WB, IHC-P, IHC-F, ICC in Human,Mouse,Rat.
Sequence QAHPYFWQCL KNALATDNHV AYSQVFKE
Cross-Reactivity (Details) No cross reactivity with other proteins.
Characteristics Rabbit IgG polyclonal antibody for Toll-like receptor 7(TLR7) detection. Tested with WB, IHC-P, IHC-F, ICC in Human,Mouse,Rat.
Gene Name: toll-like receptor 7
Protein Name: Toll-like receptor 7
Purification Immunogen affinity purified.
Immunogen A synthetic peptide corresponding to a sequence at the C-terminus of human TLR7 (1020-1047aa QAHPYFWQCLKNALATDNHVAYSQVFKE), different from the related mouse sequence by two amino acids.
Isotype IgG
Plasmids, Primers & others

Target Details TLR7

Product Details anti-TLR7 Antibody Application Details Handling References for anti-TLR7 antibody (ABIN3043948) Images back to top
Antigen
Alternative Name TLR7 (TLR7 Antibody Abstract)
Background TLR7 (Toll-like receptor 7) is protein that in humans is encoded by the TLR7 gene. Orthologs are found in mammals and birds. TLR7 is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is predominantly expressed in lung, placenta, and spleen, and lies in close proximity to another family member, TLR8, on human chromosome X. TLR7 recognises single stranded RNA in endosomes, which is a common feature of viral genomes which are internalised by macrophages.

Synonyms: PRO285 antibody|TLR 7 antibody|Tlr7 antibody|TLR7_HUMAN antibody|Toll like receptor 7 antibody|Toll-like receptor 7 antibody|UNQ248 antibody
Gene ID 51284
Pathways TLR Signaling, Activation of Innate immune Response, Toll-Like Receptors Cascades

Application Details

Product Details anti-TLR7 Antibody Target Details TLR7 Handling References for anti-TLR7 antibody (ABIN3043948) Images back to top
Application Notes WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, The detection limit for TLR7 is approximately 0.1 ng/lane under reducing conditions.
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Mouse, Rat, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
IHC-F: Concentration: 0.5-1 μg/mL, Tested Species: Human
ICC: Concentration: 0.5-1 μg/mL, Tested Species: Human
Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.
Comment

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P), IHC(F) and ICC.

Restrictions For Research Use only

Handling

Product Details anti-TLR7 Antibody Target Details TLR7 Application Details References for anti-TLR7 antibody (ABIN3043948) Images back to top
Format Lyophilized
Reconstitution Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
Concentration 500 μg/mL
Buffer Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

References for anti-TLR7 antibody (ABIN3043948)

Product Details anti-TLR7 Antibody Target Details TLR7 Application Details Handling Images back to top
Product cited in:

Esancy, Condon, Feng, Kimball, Curtright, Dhaka: "A zebrafish and mouse model for selective pruritus via direct activation of TRPA1." in: eLife, Vol. 7, 2018

Images

Product Details anti-TLR7 Antibody Target Details TLR7 Application Details Handling References for anti-TLR7 antibody (ABIN3043948) back to top
Supplier Images
Immunohistochemistry (IHC) image for anti-Toll-Like Receptor 7 (TLR7) (AA 1020-1047), (C-Term) antibody (ABIN3043948) Anti- TLR7 Picoband antibody, IHC(P) IHC(P): Human Placenta Tissue
Immunohistochemistry (IHC) image for anti-Toll-Like Receptor 7 (TLR7) (AA 1020-1047), (C-Term) antibody (ABIN3043948) Anti- TLR7 Picoband antibody, IHC(P) IHC(P): Rat Thymus Tissue
Immunohistochemistry (IHC) image for anti-Toll-Like Receptor 7 (TLR7) (AA 1020-1047), (C-Term) antibody (ABIN3043948) Anti- TLR7 Picoband antibody, IHC(F) IHC(F): Human Placenta Tissue
Western Blotting (WB) image for anti-Toll-Like Receptor 7 (TLR7) (AA 1020-1047), (C-Term) antibody (ABIN3043948) Anti- TLR7 Picoband antibody, Western blotting All lanes: Anti TLR7 at 0.5ug/ml Lane...
Immunohistochemistry (IHC) image for anti-Toll-Like Receptor 7 (TLR7) (AA 1020-1047), (C-Term) antibody (ABIN3043948) Anti- TLR7 Picoband antibody, ICC ICC: A549 Cell
Immunohistochemistry (IHC) image for anti-Toll-Like Receptor 7 (TLR7) (AA 1020-1047), (C-Term) antibody (ABIN3043948) Anti- TLR7 Picoband antibody, IHC(P) IHC(P): Mouse Thymus Tissue
Western Blotting (WB) image for anti-Toll-Like Receptor 7 (TLR7) (AA 1020-1047), (C-Term) antibody (ABIN3043948) Anti- TLR7 Picoband antibody, Western blottingAll lanes: Anti TLR7 at 0.5ug/ml Lane ...