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anti-Human COMMD1 Antibodies:
anti-Rat (Rattus) COMMD1 Antibodies:
anti-Mouse (Murine) COMMD1 Antibodies:
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Human Monoclonal COMMD1 Primary Antibody for IP, ELISA - ABIN566862
Maine, Mao, Komarck, Burstein: COMMD1 promotes the ubiquitination of NF-kappaB subunits through a cullin-containing ubiquitin ligase. in The EMBO journal 2007
Show all 9 Pubmed References
Human Polyclonal COMMD1 Primary Antibody for ELISA, WB - ABIN566860
Gkiafi, Panayotou: Comparative proteomic analysis implicates COMMD proteins as Epstein-Barr virus targets in the BL41 Burkitt's lymphoma cell line. in Journal of proteome research 2011
This study has thus revealed a novel nuclear complex of F-actin, DRR1 (show FAM107A Antibodies) and COMMD1 that is involved in NF-kappaB (show NFKB1 Antibodies) degradation and cell cycle suppression in neuroblastoma (show ARHGEF16 Antibodies) cells.
these results identify COMMD1 and an E2F-metabolic pathway as key regulators of osteoclastogenic responses under pathological inflammatory conditions
The COMMD1 downregulation by miR (show MLXIP Antibodies)-205 promotes tumor development by modulating a positive feedback loop that amplifies inflammatory- and stemness-associated properties of cancer cells.
COMMD1 plays a critical role in the termination of NF-kappaB (show NFKB1 Antibodies) activity and the control of pro-inflammatory and pro-labor mediators.
COMMD1 expression is associated with poor prognosis in diffuse large B-cell lymphoma
COMMD1 is identified as a novel regulator of misfolded protein aggregation.
COMMD1 is directly linked to early endosomes through its interaction with a protein complex containing CCDC22, CCDC93, and C16orf62.
COMMD1 is acetylated by p300 (show EP300 Antibodies) and that acetylation protects COMMD1 from XIAP (show XIAP Antibodies)-mediated proteosomal degradation
IkappaB-alpha (show NFKBIA Antibodies) protein was stabilized by COMMD1, which attenuated NF-kappaB (show NFKB1 Antibodies) signaling during Toll (show TLR4 Antibodies)-like receptor ligand and tumor necrosis factor alpha (show TNF Antibodies) treatment and enhanced HIV-1 latency in latently HIV-1-infected cells.
These data demonstrate the anti-inflammatory properties of COMMD1 in bronchial epithelial cells and open new therapeutic avenues in cystic fibrosis (show S100A8 Antibodies).
this study shows COMMD1 suppresses bone loss in inflammatory arthritis and osteolysis models of rheumatoid arthritis
Liver specific Commd1 knockout results in elevated plasma LDL cholesterol.
Alteration of COMMD1 concentration influences copper and zinc homeostasis as well as ProSAP/Shank (show SHANK2 Antibodies) protein levels.
Copper metabolism domain-containing 1 represses genes that promote inflammation and protects mice from colitis and colitis-associated cancer.
results provide the first genetic evidence for COMMD1 to play an essential role in hepatic copper homeostasis and present a valuable mouse model for further understanding of the molecular mechanisms underlying hepatic copper homeostasis
Clusterin (show CLU Antibodies) and COMMD1 independently regulate degradation of the mammalian copper ATPases ATP7A (show ATP7A Antibodies) and ATP7B (show ATP7B Antibodies).
COMMD1 as a novel protein regulating SOD1 activation and associate COMMD1 function with the production of free radicals.
COMMD1 is required to shuttle the liver copper transporter (Atp7b (show ATP7B Antibodies)) when the intracellular copper level falls below the threshold.
RNA polymerase II phosphorylated at serine 2 of the carboxyl-terminal domain repeats, a marker of transcription elongation, is enriched on the paternal allele than on the maternal allele in the Commd1 promoter
Inhibition of histone deacetylases alters allelic chromatin conformation at the imprinted U2af1-rs1 locus in mouse embryonic stem cells
COMMD1 is a regulator of copper homeostasis, sodium uptake, and NF-kappa-B (see MIM 164011) signaling (de Bie et al., 2005
COMM domain-containing protein 1
, copper metabolism gene MURR1
, protein Murr1
, COMM domain containing protein 1
, copper metabolism (Murr1) domain containing 1
, U2af1-rs1 region 1
, copper metabolism domain containing 1