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|Antigen||Calcium/calmodulin-Dependent Protein Kinase II delta (CAMK2D) Antibodies|
|Reactivity||Human, Primate Alternatives|
|Conjugate||This CAMK2D antibody is un-conjugated Alternatives|
Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
|3 references available|
|Supplier||Log in to see|
Product Details anti-CAMK2D AntibodyTarget Details CAMK2D Application Details Handling References for anti-CAMK2D antibody (ABIN359403) Images
|Specificity||This antibody detects CAMK2D at C-term.|
|Purification||Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.|
|Immunogen||This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human CAMK2 delta.|
Target Details CAMK2DProduct Details anti-CAMK2D Antibody Application Details Handling References for anti-CAMK2D antibody (ABIN359403) Images back to top
|Alternative Name||CAMK2D (CAMK2D Antibody Abstract)|
|Background||CaM-kinase II (CAMK2) is a prominent Ser/Thr protein kinase in the central nervous system that may function in long-term potentiation and neurotransmitter release. Likely autophosphorylation of Thr-286 allows the kinase to switch from a calmodulin-dependent to a calmodulin-independent state. CAMK2 is composed of four different chains: alpha, beta, gamma, and delta. The different isoforms assemble into homo- or heteromultimeric holoenzymes composed of 8 to 12 subunits. Expression of CAMK2 delta is significantly increased in patients suffering from dilated cardiomyopathy.Synonyms: CAMKD, CaM kinase II subunit delta, CaM-kinase II delta chain, CaMK-II subunit delta, Calcium/calmodulin-dependent protein kinase type II delta chain|
|Molecular Weight||56297 Da|
|Gene ID||817, 9606|
|Pathways||WNT Signaling, Interferon-gamma Pathway, Myometrial Relaxation and Contraction, Smooth Muscle Cell Migration|
Application DetailsProduct Details anti-CAMK2D Antibody Target Details CAMK2D Handling References for anti-CAMK2D antibody (ABIN359403) Images back to top
ELISA 1: 1,000. Western blot 1: 100 - 1: 500. Immunohistochemistry 1: 50 - 1: 100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
|Restrictions||For Research Use only|
HandlingProduct Details anti-CAMK2D Antibody Target Details CAMK2D Application Details References for anti-CAMK2D antibody (ABIN359403) Images back to top
|Buffer||PBS with 0.09 % (W/V) sodium azide|
|Precaution of Use||This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.|
|Handling Advice||Avoid repeated freezing and thawing.|
|Storage||4 °C/-20 °C|
|Storage Comment||Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer.|
References for anti-CAMK2D antibody (ABIN359403)Product Details anti-CAMK2D Antibody Target Details CAMK2D Application Details Handling Images back to top
Boussen, Kochbati, Besbes, Dhiab, Makhlouf, Jerbi, Gamoudi, Benna, Rahal, Maalej, Ben Ayed: "[Male secondary breast cancer after treatment for Hodgkin's disease. Case report and review of the literature]." in: Cancer radiothérapie : journal de la Société française de radiothérapie oncologique, Vol. 4, Issue 6, pp. 465-8, 2001
Hoch, Meyer, Hetzer, Krause, Karczewski: "Identification and expression of delta-isoforms of the multifunctional Ca2+/calmodulin-dependent protein kinase in failing and nonfailing human myocardium." in: Circulation research, Vol. 84, Issue 6, pp. 713-21, 1999
Tombes, Krystal: "Identification of novel human tumor cell-specific CaMK-II variants." in: Biochimica et biophysica acta, Vol. 1355, Issue 3, pp. 281-92, 1997
ImagesProduct Details anti-CAMK2D Antibody Target Details CAMK2D Application Details Handling References for anti-CAMK2D antibody (ABIN359403) back to top