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|Antigen||Calcium/calmodulin-Dependent Protein Kinase II gamma (CAMK2G) Antibodies|
|Reactivity||Human, Mouse (Murine), Primate, Rat (Rattus) Alternatives|
|Conjugate||This CAMK2G antibody is un-conjugated Alternatives|
Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
|2 references available|
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Product Details anti-CAMK2G AntibodyTarget Details CAMK2G Application Details Handling References for anti-CAMK2G antibody (ABIN359402) Images
|Specificity||This antibody detects CAMK2G at C-term.|
|Purification||Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.|
|Immunogen||This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-term region of human CAMK2 delta-like.|
Target Details CAMK2GProduct Details anti-CAMK2G Antibody Application Details Handling References for anti-CAMK2G antibody (ABIN359402) Images back to top
|Alternative Name||CAMK2G / CAMKG (CAMK2G Antibody Abstract)|
|Background||CaM-kinase II (CAMK2) is a prominent Ser/Thr protein kinase in the central nervous system that may function in long-term potentiation and neurotransmitter release. Likely autophosphorylation of Thr-286 allows the kinase to switch from a calmodulin-dependent to a calmodulin-independent state. CAMK2 is composed of four different chains: alpha, beta, gamma, and delta. The different isoforms assemble into homo- or heteromultimeric holoenzymes composed of 8 to 12 subunits.Synonyms: CaM kinase II subunit gamma, CaM-kinase II gamma chain, CaMK-II subunit gamma, Calcium/calmodulin-dependent protein kinase type II gamma chain|
|Molecular Weight||62609 Da|
|Pathways||WNT Signaling, Interferon-gamma Pathway, Hormone Transport, Myometrial Relaxation and Contraction, Regulation of long-term Neuronal Synaptic Plasticity|
Application DetailsProduct Details anti-CAMK2G Antibody Target Details CAMK2G Handling References for anti-CAMK2G antibody (ABIN359402) Images back to top
ELISA 1: 1,000. Western blot 1: 100 - 1500. Immunohistochemistry 1: 50 - 1: 100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
|Restrictions||For Research Use only|
HandlingProduct Details anti-CAMK2G Antibody Target Details CAMK2G Application Details References for anti-CAMK2G antibody (ABIN359402) Images back to top
|Buffer||PBS, 0.09 % (W/V) Sodium Azide|
|Precaution of Use||This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.|
|Handling Advice||Avoid repeated freezing and thawing.|
|Storage||4 °C/-20 °C|
|Storage Comment||Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer.|
References for anti-CAMK2G antibody (ABIN359402)Product Details anti-CAMK2G Antibody Target Details CAMK2G Application Details Handling Images back to top
Breen, Ashcroft: "Human islets of Langerhans express multiple isoforms of calcium/calmodulin-dependent protein kinase II." in: Biochemical and biophysical research communications, Vol. 236, Issue 2, pp. 473-8, 1997
Tombes, Krystal: "Identification of novel human tumor cell-specific CaMK-II variants." in: Biochimica et biophysica acta, Vol. 1355, Issue 3, pp. 281-92, 1997
ImagesProduct Details anti-CAMK2G Antibody Target Details CAMK2G Application Details Handling References for anti-CAMK2G antibody (ABIN359402) back to top