|Antigen||Frizzled Family Receptor 6 (FZD6) Antibodies|
|Conjugate||This FZD6 antibody is un-conjugated Alternatives|
Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
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Product Details anti-FZD6 AntibodyTarget Details FZD6 Application Details Handling Images
|Specificity||Reacts with Frizzled-6 (Family: GPCR, Subfamily: Frizzled)|
|Purification||Peptide Immunogen Affinity Chromatography.|
|Immunogen||Synthetic peptide - KLH conjugated|
Target Details FZD6Product Details anti-FZD6 Antibody Application Details Handling Images back to top
|Alternative Name||FZD6 (FZD6 Antibody Abstract)|
|Background||FZD6 is a Frizzled Receptor for Wnt signaling proteins involved in patterning during development. Contrary to other Frizzled proteins, FZD6 does not contain a C-terminal PDZ domain-binding motif. FZD6 is widely expressed. The Drosophila homolog activates Dishevelled. FZD6 expression has been reported in brain, colon, heart, kidney, liver, lung, ovary, pancreas, placenta, prostate, skeletal muscle, small intestine, testis, and thymus. Various tumor cell lines have also been shown to express FZD6. ESTs have been isolated from blood, brain, breast, connective tissue, liver, liver/spleen, lung, placenta, testis, thyroid, and vessel libraries. In addition, several ESTs have been isolated from tumor libraries.Synonyms: Frizzled-6, Fz-6, hFz6|
|Pathways||WNT Signaling, Tube Formation|
Application DetailsProduct Details anti-FZD6 Antibody Target Details FZD6 Handling Images back to top
Immunocytochemistry. Immunohistochemistry with acetone fixed frozen and formalin fixed paraffin embedded tissues: 6-14 μg/mL Antigen retrieval: Steam slides in 0.01 M sodium citrate buffer, pH 6.0, at 99-100 °C for 20 min. Remove from heat and let stand at room temperature in buffer for 20 min. Rinse in 1x TBS with Tween (TBST) for 1 min. at room temperature.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. Further Comments: This product was originally produced by MBL International.
|Restrictions||For Research Use only|
HandlingProduct Details anti-FZD6 Antibody Target Details FZD6 Application Details Images back to top
|Buffer||PBS containing 0.09 % Sodium Azide as preservative.|
|Precaution of Use||This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.|
|Storage||4 °C/-20 °C|
Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C to -70 °C forlonger. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
|Expiry Date||12 months|
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