Use your antibodies-online credentials, if available.
No Products on your Comparison List.
Your basket is empty.
Find out more
Show all species
Show all synonyms
Select your species and application
anti-Mouse (Murine) WNT1 Antibodies:
anti-Human WNT1 Antibodies:
anti-Rat (Rattus) WNT1 Antibodies:
Go to our pre-filtered search.
Human Polyclonal WNT1 Primary Antibody for IF (p), IHC (p) - ABIN733748
Gao, Liu, Chen, Lv, Wu, Mi, Wang: Comparative study of Hsp27, GSK3?, Wnt1 and PRDX3 in Hirschsprung's disease. in International journal of experimental pathology 2014
Show all 4 Pubmed References
Polyclonal WNT1 Primary Antibody for ELISA, WB - ABIN539515
He, Sheng, Stelter, Li, Zhang, Sinha, Luxon, Xie: Suppressing Wnt signaling by the hedgehog pathway through sFRP-1. in The Journal of biological chemistry 2006
Show all 3 Pubmed References
Human Polyclonal WNT1 Primary Antibody for WB - ABIN3042350
Dong, Duan, Han, Zhang, Wu: Suppression of wingless-type MMTV integration site family, member 1 expression by small interfering RNA inhibits U251 glioma cell growth in vitro. in Oncology letters 2014
Show all 2 Pubmed References
Human Monoclonal WNT1 Primary Antibody for ICC, FACS - ABIN969458
Toffart, Moro-Sibilot, Couraud, Merle, Perol, Girard, Souquet, Mastroianni, Ferretti, Romand, Chatellain, Vesin, Brambilla, Brambilla, Timsit: Evaluation of RECIST in chemotherapy-treated lung cancer: the Pharmacogenoscan Study. in BMC cancer 2015
Human Polyclonal WNT1 Primary Antibody for ELISA, ICC - ABIN6266035
Tang, Peng, Huang, Xie, Chen, Shen, Gao, You, Xie, Chen: Neoisoliquiritigenin Inhibits Tumor Progression by Targeting GRP78-β- catenin Signaling in Breast Cancer. in Current cancer drug targets 2018
maternal Wnt/STOP signaling, but not beta-catenin signaling, has a role in cleavage after fertilization and cell cycle progression
sfrp1 promotes cardiomyocyte differentiation in Xenopus via negative-feedback regulation of Wnt signalling.
analysis of differential role of Axin RGS domain function in Wnt signaling during anteroposterior patterning and maternal axis formation
Data show taht combined Wnt and Nodal signaling synergistically activates transcription of Spemann organizer genes.
The authors propose that these dual functions of DP1 can promote and stabilize biphasic Wnt-on and Wnt-off states in response to a gradual gradient of Wnt/beta-catenin signalling to determine differential cell fates.
aberrant expression of AF1q may activate Wnt/beta-catenin signaling and result in podocyte injury.
Wnt1a maintains characteristics of dermal papilla cells that induce mouse hair regeneration in a 3D preculture system
These data suggested that Wnt/beta-catenin pathway might be a potential target to treat the LPS-induced inflammation in ALI.
Wnt signaling regulates airway epithelial stem cells in adult murine submucosal glands.
Pax9-dependent Wnt signaling has a role in palatogenesis and cleft palates
Data show that autocrine Wnt secretion is important for the survival, chromosomal stability, differentiation, and tumorigenic potential of embryonic stem cells (ESCs).
Results demonstrated functional differences in the molecular mechanisms downstream of Wnt1 function in the diencephalon, in relation to the spinal cord. Wnt1 signal determines the patterning of the diencephalic dorso-ventral axis
Data show that both transgenic Wnt1-cre and P0-cre are similarly effective in deleting beta-catenin in the neural crest.
data suggest that WNT1-related osteogenesis imperfecta and osteoporosis are caused in part by decreased mTORC1-dependent osteoblast function resulting from loss of WNT1 signaling in osteocytes.
Administration of EET alters Wnt1, NOV, and HO-1 signaling to prevent obesity-induced cardiomyopathy in obese mice.
Data indicate that Wnt1 proto-oncogene protein (WNT1) is the direct target of microRNA miR-34a in dendritic cell (DC).
In order to evaluate the function of IFT88 in regulating craniofacial development, we generated Wnt1-Cre;Ift88fl/fl mice to eliminate Ift88 specifically in cranial neural crest (CNC) cells. Wnt1-Cre;Ift88fl/flpups died at birth due to severe craniofacial defects including bilateral cleft lip and palate and tongue agenesis, following the loss of the primary cilia in the CNC-derived palatal mesenchyme
Wnt, Eda, and Shh have roles in touch dome Merkel cell development
The data obtained from the 14-3-3epsilon/14-3-3zeta/Wnt1-Cre mice strongly indicate the importance of 14-3-3 proteins in the development of melanocyte lineages.
High WNT1 promoted stem-ness characteristics and metastasis potential in sphere-forming liver cancer stem cells.
Decreased expressions of Wnt1 and Wnt5a.
we provide unequivocal evidence that epithelial-derived Wnt1 is sufficient to drive interstitial fibrosis in the absence of any injury.
SOXC proteins act cell- and non-cell-autonomously in perichondrocytes and chondrocytes to establish noncanonical WNT signaling crosstalk essential for growth plate induction and control
Data show that elongator protein 3 (Elp3) trigger Wnt-driven tumor initiation in the intestine, and Elp3 deficiency strongly impaired radiation-induced intestinal regeneration.
Fasudil prevents loss of dopamine neurons in the MPTP mice model of PD through inflammatory inhibition via activation of PI3K/p-Akt and WNT1/Fzd1/beta-catenin cell signaling pathways.
MiR301a increased the radiosensitivity and inhibited the migration of radioresistantESCC cells by targeting WNT1.
The WNT1 mutation disrupts feedback regulation between these miRNAs and WNT1, providing insights into the pathogenesis of WNT-related bone disorders. These miRNAs may have potential in the diagnosis and treatment of osteoporosis.
Taking together, these results suggest that Wnt/beta-catenin signal pathway activation-dependent up-regulation of syncytin-1 contributes to the pro-inflammatory factor TNF-alpha-enhanced fusion between oral squamous cell carcinoma cells and endothelial cells.
High WNT1 expression is associated with metastasis in cholangiocarcinoma.
We conclude that severe form of osteogenesis imperfecta (OI) may be associated with WNT1 mutation. This novel variant of WNT1 identified in achild with OI is likely cause for the disease.
MiR-185 inhibits colon cancer cell proliferation and invasion by targeting Wnt1.
High WNT1 expression is associated with epithelial-mesenchymal transition in gastric cancer.
Biallelic pathogenic splice acceptor site variant (c.359-3C>G) in WNT1 gene located on chromosome 12q13.12 underlying osteogenesis imperfecta type 3 in a Pakistani family.
Vertebral compression fractures were present in 78% (7/9) of those aged over 50years but were not seen in younger mutation-positive subjects. All those with fractures had several severely compressed vertebrae. Altogether spinal compression fractures were present in 39% of those with a WNT1 mutation. Only
miR-218 promoted the apoptosis of human ovarian carcinoma cells via suppression of the WNT/beta-catenin signaling pathway.
Data suggest that brain imaging be performed in any individual with WNT1-associated osteogenesis imperfecta (OI) who also has developmental delay or any neurological deficits.
Data indicate a tetracyclic azafluorenone, SJ26, that is capable of binding to G-quadruplex DNA structure, repressing WNT1 expression, and inhibiting cell migration.
Regulation of WNT signaling by VSX2 during optic vesicle patterning in human induced pluripotent stem cells has been described.
High WNT1 expression is associated with metastasis in triple-negative breast cancer.
WNT1 osteoporosis causes significant skeletal changes already in early childhood and impairs bone mass gain during pubertal years.
High WNT1 expression is associated with esophageal squamous cell carcinoma.
High WNT1 expression in stromal cells is associated with myelodysplastic syndrome.
High WNT1 expression is associated with gastric cancer.
Novel compound heterozygous WNT1 missense mutations, p.Glu123Asp and p.Cys153Gly, identified in a patient with osteogenesis imperfecta.
Osteocyte protein expression is altered in patients with osteoporosis caused by WNT1 mutation.
Data indicate that Wnt-1 protein is present in postdevelopmental endothelial cells where it associates with cytoskeletal elements and may retain function as a tissue polarity gene.
Rspo1-Wnt-VegfC-Vegfr3 signaling plays a crucial role as an endothelial-autonomous permissive cue for developmental angiogenesis.
wnt1 and wnt10b are required to maintain threshold levels of Pax2.1 and Fgf8 at the midbrain-hindbrain boundary.
novel role for Wnt/beta-catenin signalling in determining endocardial cell fate
In zebrafish embryos lacking Wnt3a, Wnt1 and Wnt10b, the expression of engrailed orthologs, pax2a and fgf8 is not maintained after mid-somitogenesis
two Dvl-associated paralogs, Dpr1 and Dpr2, participate in distinct Wnt-dependent developmental processes
Wnt/Axin/beta-catenin pathway has a role in ventral CNS development
The boundary and roof plate expression of wnt1 each contribute to upregulation of proneural and delta gene expression and neurogenesis in non-boundary regions.
Epistatic analyses suggest a possible genetic interaction between Wnt/beta-catenin and Myostatin in regulation of slow and fast twitch muscle myofibrillogenesis
The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It is very conserved in evolution, and the protein encoded by this gene is known to be 98% identical to the mouse Wnt1 protein at the amino acid level. The studies in mouse indicate that the Wnt1 protein functions in the induction of the mesencephalon and cerebellum. This gene was originally considered as a candidate gene for Joubert syndrome, an autosomal recessive disorder with cerebellar hypoplasia as a leading feature. However, further studies suggested that the gene mutations might not have a significant role in Joubert syndrome. This gene is clustered with another family member, WNT10B, in the chromosome 12q13 region.
, protein Wnt-1
, proto-oncogene Int-1
, proto-oncogene Wnt-1
, proto-oncogene protein Wnt-1
, proto-oncogene Int-1 homolog
, wingless-type MMTV integration site family, member 1 (oncogene INT1)
, Wingless-type MMTV integration site 1 homolog
, Wingless-type MMTV integration site 1, homolog
, wingless-related MMTV integration site 1
, murine mammary tumor virus integration site
, wingless-type MMTV integration site family member 1