|Antigen||Wingless-Type MMTV Integration Site Family, Member 10B (WNT10B) Antibodies|
|Reactivity||Human, Mouse (Murine), Rat (Rattus) Alternatives|
|Conjugate||This WNT10B antibody is un-conjugated Alternatives|
Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
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Product Details anti-WNT10B AntibodyTarget Details WNT10B Application Details Handling Images
|Specificity||This antibody detects WNT10B. The Wnt10b antibody will not cross-react with Wnt10a.|
|Cross-Reactivity (Details)||Species reactivity (tested):Human, mouse, rat|
|Immunogen||Wnt10b antibody was raised against a 15 amino acid peptide from near the center of human Wnt10b.|
Target Details WNT10BProduct Details anti-WNT10B Antibody Application Details Handling Images back to top
|Alternative Name||WNT10B (WNT10B Antibody Abstract)|
|Background||Wnt10b is a member of the Wnt family, a gene family that encodes secreted signaling proteins that play crucial roles in normal development such as regulation of cell fate and patterning during embryogenesis as well as neoplastic transformation. Wnt10b is found in the mouse mammary tumor virus insertion site where it is activated and causes mammary tumors. Elevated levels of Wnt10b have also been detected in human breast carcinomas. Wnt10b is known to be involved in adipogenesis, maintaining the preadipocyte in an undifferentiated state. More recently, Wnt10b has been shown to promote epithelial cell differentiation and hair shaft growth, demonstrating that Wnt10b has multiple roles in cell growth and differentiation. Two isoforms of Wnt10b are known to exist, this antibody will only recognize the longer isoform.Synonyms: Protein Wnt-10b, WNT12, Wnt-12|
|Pathways||WNT Signaling, Skeletal Muscle Fiber Development|
Application DetailsProduct Details anti-WNT10B Antibody Target Details WNT10B Handling Images back to top
ELISA. Western blot. Immunohistochemistry on paraffin sections: 2 - 4 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
|Restrictions||For Research Use only|
HandlingProduct Details anti-WNT10B Antibody Target Details WNT10B Application Details Images back to top
|Buffer||PBS containing 0.02 % sodium azide|
|Precaution of Use||This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.|
|Handling Advice||Avoid repeated freezing and thawing.|
|Storage||4 °C/-20 °C|
|Storage Comment||Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.|