CD47 Proteins (CD47)

CD47 encodes a membrane protein, which is involved in the increase in intracellular calcium concentration that occurs upon cell adhesion to extracellular matrix. Additionally we are shipping CD47 Antibodies (319) and CD47 Kits (12) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
CD47 16423 Q61735
CD47 961 Q08722
CD47 29364 P97829
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Top CD47 Proteins at antibodies-online.com

Showing 10 out of 49 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_HEK-293 Cells Human AVI tag,Biotin,His tag Biotinylated Human CD47, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%. Immobilized Anti-CD47 MAb, Human IgG4 at 2μg/mL (100 μL/well) can bind Biotinylated Human CD47, His Tag  with a linear range of 0.07-0.84 ng/mL. 200 μg Log in to see 5 Days
$1,518.00
Details
HOST_HEK-293 Cells Human His tag Human CD47, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%. Immobilized Human SIRP alpha, Fc Tag  with a linear range of 1.56-12.5 ng/mL. 50 μg Log in to see 2 to 3 Days
$308.00
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 30 to 35 Days
$4,331.68
Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 50 to 55 Days
$6,041.49
Details
HOST_HEK-293 Cells Rat Fc Tag Rat CD47, Fc Tag on SDS-PAGE under reducing (R) and no-reducing (NR) conditions. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%. 100 μg Log in to see 5 Days
$319.00
Details
HOST_HEK-293 Cells Human His tag 10 μg Log in to see 2 to 3 Days
$200.00
Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 50 to 55 Days
$4,244.78
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 30 to 35 Days
$4,331.68
Details
HOST_HEK-293 Cells Human AVI tag,His tag   50 μg Log in to see 2 to 3 Days
$515.63
Details
HOST_HEK-293 Cells Cynomolgus Fc Tag Cynomolgus CD47, Fc Tag on SDS-PAGE under reducing (R) and no-reducing (NR) conditions. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%. 100 μg Log in to see 5 Days
$319.00
Details

CD47 Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine) , , ,
, ,
Human , , , , , , , ,
, , , , , , , , , ,
Rat (Rattus) ,
,

More Proteins for CD47 Interaction Partners

Mouse (Murine) CD47 interaction partners

  1. TSP1 (show GZMA Proteins) significantly accelerates replicative senescence and associated cell cycle arrest in a CD47-dependent manner.

  2. CD47, TSP1 (show GZMA Proteins), and to a lesser extent SIRPalpha facilitate exosome-mediated myeloid-derived suppressor cells chemotaxis and migration.

  3. In pulmonary hypertension TSP1 (show GZMA Proteins)-CD47 is upregulated, and contributes to pulmonary arterial vasculopathy and dysfunction.

  4. thrombospondin-1 (show THBS1 Proteins) via CD47 inhibits renal tubular epithelial cell recovery after ischemia reperfusion injury through inhibition of proliferation/self-renewal.

  5. these findings have demonstrated how tumor cells inhibit innate sensing in dendritic cells and suggested that the CD47-SIRPalpha axis is critical for dendritic cell-driven antitumor immunity

  6. this study shows that CD47 deficiency in tumor stroma promotes tumor progression by enhancing angiogenesis

  7. the results obtained by combining bioinformatics and preclinical studies strongly suggest that targeting TSP-1 (show GZMA Proteins)/CD47 axis may represent a valuable therapeutic alternative for hampering melanoma spreading.

  8. These results identify CD47 as an important regulator of LFA-1 (show ITGAL Proteins) and VLA-4 integrin-adhesive functions in T cell proliferation.

  9. Treg cells protect dopaminergic neurons against MPP+ neurotoxicity by a cell-to-cell contact mechanism underlying CD47-SIRPA (show SIRPA Proteins) interaction and Rac1/Akt (show AKT1 Proteins) activation.

  10. CD47 deficient mice with vaccination showed greater protective efficacy against lethal challenge.

Human CD47 interaction partners

  1. In pulmonary hypertension TSP1 (show THBS1 Proteins)-CD47 is upregulated, and contributes to pulmonary arterial vasculopathy and dysfunction.

  2. thrombospondin-1 (show THBS1 Proteins) via CD47 inhibits renal tubular epithelial cell recovery after ischemia reperfusion injury through inhibition of proliferation/self-renewal.

  3. Engineering macrophages to eat cancer: from "marker of self" CD47 and phagocytosis to differentiation

  4. the results obtained by combining bioinformatics and preclinical studies strongly suggest that targeting TSP-1 (show THBS1 Proteins)/CD47 axis may represent a valuable therapeutic alternative for hampering melanoma spreading.

  5. Results indicated that surgical resection combined with anti-CD47 blocking immunotherapy promoted an inflammatory response and prolonged survival in xenograft animal model, and is therefore an attractive strategy for clinical translation.

  6. Results show that the stronger expression of CD47 by cancer cells and larger number of total macrophages/M2 were independently related to shorter survivals.

  7. Prolongation of transient porcine chimerism via transgenic expression of human CD47 in a primate model is associated with an immune modulating effect, leading to markedly prolonged survival of donor swine skin xenografts.

  8. CD47 is a promising cancer biomarker, and targeting CD47 presents an effective and potential therapeutic strategy through synthesized mechanisms

  9. CD47 seems to mediate fusion mostly through broad contact surfaces between the partners' cell membrane while syncytin-1 (show ERVW-1 Proteins) mediate fusion through phagocytic-cup like structure.

  10. The results suggested a critical role of CD47 in laryngeal squamous cell carcinoma development.

Pig (Porcine) CD47 interaction partners

  1. Amyloid-beta inhibits No-cGMP signaling in a CD36 (show CD36 Proteins)- and CD47-dependent manner

  2. Genetic induction of human CD47 on porcine cells could provide inhibitory signaling to SIRPalpha on human macrophages, providing a novel approach to preventing macrophage-mediated xenograft rejection.

Cow (Bovine) CD47 interaction partners

CD47 Protein Profile

Protein Summary

This gene encodes a membrane protein, which is involved in the increase in intracellular calcium concentration that occurs upon cell adhesion to extracellular matrix. The encoded protein is also a receptor for the C-terminal cell binding domain of thrombospondin, and it may play a role in membrane transport and signal transduction. This gene has broad tissue distribution, and is reduced in expression on Rh erythrocytes. Alternatively spliced transcript variants have been found for this gene.

Gene names and symbols associated with CD47 Proteins (CD47)

  • CD47 antigen (Rh-related antigen, integrin-associated signal transducer) (Cd47)
  • CD47 molecule (CD47)
  • Cd47 molecule (Cd47)
  • 9130415E20Rik protein
  • AA407862 protein
  • AI848868 protein
  • AW108519 protein
  • B430305P08Rik protein
  • CD47/IAP protein
  • IAP protein
  • Itgp protein
  • MER6 protein
  • OA3 protein

Protein level used designations for CD47 Proteins (CD47)

Rh-related antigen , integrin-associated protein , leukocyte surface antigen CD47 , CD47 antigen (Rh-related antigen, integrin-associated signal transducer) , CD47 glycoprotein , antigen identified by monoclonal antibody 1D8 , antigenic surface determinant protein OA3 , integrin associated protein , integrin-associated signal transducer , CD47 antigen , IAP

GENE ID SPECIES
16423 Mus musculus
961 Homo sapiens
478552 Canis lupus familiaris
397042 Sus scrofa
282661 Bos taurus
101111153 Ovis aries
29364 Rattus norvegicus
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