anti-Centromere Protein B (CENPB) Antibodies

CENPB product is a highly conserved protein that facilitates centromere formation. Additionally we are shipping Centromere Protein B Kits (39) and Centromere Protein B Proteins (8) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
CENPB 12616 P27790
CENPB 362217  
CENPB 1059 P07199
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Top anti-Centromere Protein B Antibodies at antibodies-online.com

Showing 10 out of 41 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-CENPB Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:500Positive Control: Jurkat cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Dog Rabbit Un-conjugated WB 50 μg Log in to see 7 to 9 Days
$551.83
Details
Human Rabbit Un-conjugated ICC, IF CENP-B pAb tested by immunofluorescence. Staining of HeLa cells with CENP-B pAb at a 1 µg/ml dilution (green) and α-tubulin (red, Catalog No. 39527) at 1 µg/ml. 100 μg Log in to see 1 to 2 Days
$495.83
Details
Human Rabbit Un-conjugated ICC, IF, IHC 0.1 mL Log in to see 7 to 9 Days
$538.13
Details
Human Rabbit Alexa Fluor 350 IF (p)   100 μL Log in to see 14 to 21 Days
$405.90
Details
Human Rabbit Alexa Fluor 488 IF (p)   100 μL Log in to see 14 to 21 Days
$405.90
Details
Human Rabbit Alexa Fluor 555 IF (p)   100 μL Log in to see 14 to 21 Days
$405.90
Details
Human Rabbit Alexa Fluor 594 IF (p)   100 μL Log in to see 14 to 21 Days
$405.90
Details
Human Rabbit Alexa Fluor 647 IF (p)   100 μL Log in to see 14 to 21 Days
$405.90
Details
Human Rabbit Cy3 IF (p)   100 μL Log in to see 14 to 21 Days
$405.90
Details

CENPB Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-Centromere Protein B Antibodies

  1. Cow (Bovine) Polyclonal CENPB Primary Antibody for WB - ABIN2784717 : Orthaus, Biskup, Hoffmann, Hoischen, Ohndorf, Benndorf, Diekmann: Assembly of the inner kinetochore proteins CENP-A and CENP-B in living human cells. in Chembiochem : a European journal of chemical biology 2007 (PubMed)

More Antibodies against Centromere Protein B Interaction Partners

Mouse (Murine) Centromere Protein B (CENPB) interaction partners

  1. demonstrate a novel ADA3 (show TADA3 Antibodies) interaction with CENP-B-centromere that may account for its previously known function in mitosis

  2. Cenpa (show CENPA Antibodies), Cenpb, and Bub3 (show BUB3 Antibodies), but not Cenpc (show CENPC1 Antibodies), interacted with PARP-1 (show PARP1 Antibodies)

  3. This study shows that ICP0 induces the proteasomal-dependent degradation of the centromeric protein CENP-B in infected as well as ICP0-expressing cells.

  4. Propose that CENP-B plays a dual role in centromere formation, ensuring de novo formation on DNA lacking a functional centromere but preventing the formation of excess centromeres on chromosomes.

Human Centromere Protein B (CENPB) interaction partners

  1. Findings indicate that expression of the scleroderma autoantigens IFI-16 (show IFI16 Antibodies) and CENPs (show APITD1 Antibodies), which are associated with severe vascular disease, is increased in vascular progenitors and mature endothelial cells. High level, lineage-enriched expression of autoantigens may explain the striking association between clinical phenotypes and the immune targeting of specific autoantigens.

  2. The results indicated that CENPB boxes are highly conserved in Down syndrome (DS) patients and may not be responsible for Chr21 nondisjunction events. However, alphasatDNA in Chr21 is variable and deoxynucleotide deletions, mutations and polymorphisms may act as potential molecular diagnostic markers of DS.

  3. CENP-B directly binds both CENP-A's amino-terminal tail and CENP-C (show CENPC1 Antibodies), a key nucleator of kinetochore assembly

  4. The results revealed that CENP-B binding in the vicinity of the CENP-A (show CENPA Antibodies) nucleosome substantially stabilizes the CENP-A (show CENPA Antibodies) nucleosome on alphoid DNA in human cells.

  5. Centromere protein B (CENP-B) as a novel interacting partner of HBZ (show HBZ Antibodies).

  6. INMAP as a model regulator of CENP-B

  7. N-terminal methylation is required for CENP-B's binding to the CENP-B box.

  8. Human Nap1 (show IL8 Antibodies), an acidic histone chaperone, inhibited the non-specific binding of CENP-B to nucleosomes and apparently stimulated CENP-B binding to its cognate CENP-B box DNA.

  9. CENP-A (show CENPA Antibodies) and/or B status is predictive of the extent of skin involvement over time in systemic sclerosis.

  10. Anti-CENP-B autoantibodies in breast cancer patients prolong disease-free and overall survival.

Centromere Protein B (CENPB) Antigen Profile

Protein Summary

This gene product is a highly conserved protein that facilitates centromere formation. It is a DNA-binding protein that is derived from transposases of the pogo DNA transposon family. It contains a helix-loop-helix DNA binding motif at the N-terminus, and a dimerization domain at the C-terminus. The DNA binding domain recognizes and binds a 17-bp sequence (CENP-B box) in the centromeric alpha satellite DNA. This protein is proposed to play an important role in the assembly of specific centromere structures in interphase nuclei and on mitotic chromosomes. It is also considered a major centromere autoantigen recognized by sera from patients with anti-centromere antibodies.

Gene names and symbols associated with CENPB

  • CENP-B protein (CENP-B) antibody
  • centromere protein B (Cenpb) antibody
  • centromere protein B-like (LOC100356278) antibody
  • centromere protein B, 80kDa (CENPB) antibody
  • CENP-B antibody
  • CENPB antibody

Protein level used designations for CENPB

CENP-B protein , centromere protein B , Major centromere autoantigen B , CENP-B , centromere autoantigen B , major centromere autoantigen B , centromere autoantigen protein B

GENE ID SPECIES
443351 Ovis aries
12616 Mus musculus
362217 Rattus norvegicus
100689274 Cricetulus griseus
100356278 Oryctolagus cuniculus
1059 Homo sapiens
485791 Canis lupus familiaris
788381 Bos taurus
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