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anti-Cytochrome P450, Family 1, Subfamily A, Polypeptide 2 (CYP1A2) Antibodies

CYP1A2 encodes a member of the cytochrome P450 superfamily of enzymes. Additionally we are shipping CYP1A2 Kits (30) and CYP1A2 Proteins (9) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
CYP1A2 1544 P05177
CYP1A2 13077 P00186
CYP1A2 24297 P04799
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Top anti-CYP1A2 Antibodies at antibodies-online.com

Showing 10 out of 161 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated IHC, ELISA Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue, using Cytochrome P450 1A2 Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Rabbit Un-conjugated EIA, IF, IHC (p), WB Confocal immunofluorescent analysis of CYP1A2 Antibody (Center) Cat.-No AP51164PU-N f with 293 cell followed by Alexa Fluor®488-conjugated Goat anti-Rabbit lgG (green). DAPI was used to stain the cell nuclear (blue). Formalin fixed, paraffin embedded Human liver tissue stained with CYP1A2 Antibody (Center) followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of CYP1A2 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated. 0.4 mL Log in to see 6 to 8 Days
$401.50
Details
Mouse Goat Un-conjugated ELISA, WB 0.1 mg Log in to see 2 to 3 Days
$433.13
Details
Human Rabbit Un-conjugated IF, IHC (p), WB Confocal immunofluorescent analysis of CYP1A2 Antibody (Center) (ABIN655272) with 293 cell followed by Alexa Fluor® 488-conjugated goat anti-rabbit lgG (green). DAPI was used to stain the cell nuclear (blue). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Mouse Un-conjugated FACS, IHC, WB HEK293T cells transfected with either RC221636 overexpress plasmid (Red) or empty vector control plasmid (Blue) were immunostained by anti-CYP1A2 antibody (ABIN2453827), and then analyzed by flow cytometry. HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY CYP1A2 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 µg per lane) were separated by SDS-PAGE and immunoblotted with anti-CYP1A2. 100 μL Log in to see 2 to 3 Days
$423.50
Details
Human Rabbit Un-conjugated IHC (p), WB Anti-Cytochrome P450 1A2 antibody, IHC(P) IHC(P): Rat Liver Tissue Anti-Cytochrome P450 1A2 antibody, Western blotting Lane 1: Rat Liver Tissue Lysate Lane 2: Rat Liver Tissue Lysate Lane 3: SMMC Cell Lysate Lane 4: HEPA Cell Lysate 100 μg Log in to see 4 to 6 Days
$200.00
Details
Human Rabbit Un-conjugated IHC (p), WB Anti- CYP1A2 Picoband antibody, IHC(P) IHC(P): Human Liver Cancer Tissue Anti- CYP1A2 Picoband antibody, IHC(P) IHC(P): Mouse Liver Tissue 100 μg Log in to see 4 to 6 Days
$240.00
Details
Human Mouse Un-conjugated FACS, IHC (p), WB 100 μL Log in to see 8 to 10 Days
$493.17
Details
Human Rabbit Un-conjugated IF (p), IHC (p), WB Formalin-fixed and paraffin embedded rat liver labeled with Anti-P450 1A2/CYP1A2 Polyclonal Antibody, Unconjugated (ABIN742470) followed by conjugation to the secondary antibody and DAPI staining Formalin-fixed and paraffin embedded rat liver labeled with Anti-P450 1A2/CYP1A2 Polyclonal Antibody, Unconjugated (ABIN742470) at 1:200 followed by conjugation to the secondary antibody and DAB staining 100 μL Log in to see 3 to 7 Days
$269.50
Details
Human Mouse Un-conjugated WB CYP1A2 Antibody  western blot analysis in SK-BR-3 cell line lysates (35ug/lane).This demonstrates the CYP1A2 antibody detected the CYP1A2 protein (arrow). 0.1 mL Log in to see 10 to 11 Days
$324.50
Details

CYP1A2 Antibodies by Reactivity, Application, Clonality and Conjugate

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Top referenced anti-CYP1A2 Antibodies

  1. Human Polyclonal CYP1A2 Primary Antibody for EIA, IF - ABIN951775 : Gentile, Borro, Lala, Missori, Simmaco, Martelletti: Genetic polymorphisms related to efficacy and overuse of triptans in chronic migraine. in The journal of headache and pain 2010 (PubMed)
    Show all 5 references for ABIN951775

  2. Human Polyclonal CYP1A2 Primary Antibody for IHC, ELISA - ABIN1534375 : Corchero, Pimprale, Kimura, Gonzalez: Organization of the CYP1A cluster on human chromosome 15: implications for gene regulation. in Pharmacogenetics 2001 (PubMed)

More Antibodies against CYP1A2 Interaction Partners

Rabbit Cytochrome P450, Family 1, Subfamily A, Polypeptide 2 (CYP1A2) interaction partners

  1. CYP1A1 (show CYP1A1 Antibodies) and CYP1A2 localization into different lipid microdomains is governed by their N-terminal and internal protein regions

  2. Removal of cholesterol (an important constituent of ordered domains) led to the relocation of CYP1A2, CYP2B4 and CPR (show POR Antibodies) to the disordered regions.

  3. Oxidation kinetics of toluene in CYP1A2-CYP2B4 mixtures with and without cytochrome p450 reductase (CPR (show POR Antibodies)) are consistent with a model in which CYP1A2 has a higher affinity for CPR (show POR Antibodies) binding.

Human Cytochrome P450, Family 1, Subfamily A, Polypeptide 2 (CYP1A2) interaction partners

  1. niclosamide was subjected to efficient metabolic reactions hydroxylation and glucuronidation, wherein CYP1A2 and UGT1A1 (show UGT1A1 Antibodies) were the main contributing enzymes, respectively.

  2. Pregnane X receptor (show NR1I2 Antibodies) likely regulates CYP1A2 expression in 3D spheroids of liver cancer cells.

  3. The results of this study suggest that the CYP1A2*1F polymorphism is associated with super-refractory schizophrenia.

  4. This large meta-analysis suggests no significant effect of the investigated CYP1A2 SNPs on cancer overall risk under various genetic models

  5. CYP1A2 rs762551 polymorphism is a protective factor for bladder cancer.

  6. CYP (show PPIG Antibodies) rs2470890 allele 'C' showed an association with T2DM only when the interaction with coffee was considered, thereby setting an example of genetic activation by dietary changes associating with metabolic syndrome.

  7. CYP1A2 metabolizes E2 to generate the potent anti-tumor agent 2-ME in HCC (show FAM126A Antibodies).

  8. For the computed CYP (show PPIG Antibodies) 1A2 binding affinities, the model showed a root mean square error of 4.1 kJ mol (show DUOXA1 Antibodies)-1 and a standard error in prediction in cross-validation of 4.3 kJ mol (show DUOXA1 Antibodies)-1.

  9. phenotypic association studies in population in Nigeria: Data suggest polymorphisms in CYP1A2 exist in the population studied; distribution of CYP1A2 activity is bimodal; influence of age/sex on activity are not significant in this biomarker study.

  10. Dietary tocopherols inhibit PhIP (show PHIP Antibodies)-induced prostate carcinogenesis in CYP1A2-humanized transgenic mice.

Mouse (Murine) Cytochrome P450, Family 1, Subfamily A, Polypeptide 2 (CYP1A2) interaction partners

  1. our results suggest a more important contribution of CYP1A2 (show CYP1A1 Antibodies) to the in vivo plasma clearance and thus detoxification of 4-Aminobiphenyl

  2. hepatic CYP1A2 (show CYP1A1 Antibodies) plays a critical role in the attenuation of hyperoxic lung injury by decreasing lipid peroxidation and oxidative stress in vivo.

  3. Aryl hydrocarbon receptor (show AHR Antibodies) mediated induction of hepatic CYP1A1 (show CYP1A1 Antibodies)/1A2 is dependent on the presence of ctnnb1 (show CTNNB1 Antibodies).

  4. Results indicate Cyp1a2 (show CYP1A1 Antibodies) genotype is important in susceptibility to PCB (show PC Antibodies)-induced deficits in learning and memory.

  5. Miroestrol and deoxymiroestrol significantly up-regulated CYP2B9 while suppressing CYP1A2 (show CYP1A1 Antibodies) at both transcriptional and enzymatic levels.

  6. A report of uroporphyria development in Cyp1a2 (show CYP1A1 Antibodies)-/- mice additionally null for both alleles of the hemochromatosis (Hfe (show HFE Antibodies)) gene and heterozygous for deletion of the uroporphyrinogen decarboxylase (Urod (show UROD Antibodies)) gene (genotype: Cyp1a2 (show CYP1A1 Antibodies)-/-;Hfe (show HFE Antibodies)-/-;Urod (show UROD Antibodies)+/-).

  7. High levels of maternal hepatic CYP1A2 (show CYP1A1 Antibodies) protect against deficits in learning and memory in offspring exposed to a mixture of coplanar and noncoplanar PCBs; high-affinity AHR (show AHR Antibodies) is the next most important factor in protection of offspring.

  8. In rodents, aristolochic acid demethylation, mediated by CYP1A2 (show CYP1A1 Antibodies), is a primary pathway of aristolochic acid detoxication.

  9. The expression of Cyp1a1 (show CYP1A1 Antibodies), Cyp1a2 (show CYP1A1 Antibodies), and OGG1genes was significantly up-regulated in mice given diets containing 375 ppm dicyclanil or more.

  10. the TRE (show TREH Antibodies) element in E1 is essential for constitutive expression of the mouse Cypla2 gene

Pig (Porcine) Cytochrome P450, Family 1, Subfamily A, Polypeptide 2 (CYP1A2) interaction partners

  1. This study demonstrated for the first time that the serum testosterone level is one of the physiological factors which regulate constitutive expression of hepatic CYP1A1 (show CYP1A1 Antibodies) and CYP1A2 in pigs.

  2. The findings demonstrate a gender-related difference in the constitutive expression of hepatic CYP1A2 in Meishan pigs and further indicate that testosterone down-regulates the constitutive gene expression of the enzyme.

  3. Purification, molecular cloning, heterologous expression and characterization of pig CYP1A2

  4. Effect of beta-napthoflavone on AHR (show AHR Antibodies)-related gene, CYP1A2, in the pig is reported.

CYP1A2 Antigen Profile

Protein Summary

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. The protein encoded by this gene localizes to the endoplasmic reticulum and its expression is induced by some polycyclic aromatic hydrocarbons (PAHs), some of which are found in cigarette smoke. The enzyme's endogenous substrate is unknown\; however, it is able to metabolize some PAHs to carcinogenic intermediates. Other xenobiotic substrates for this enzyme include caffeine, aflatoxin B1, and acetaminophen. The transcript from this gene contains four Alu sequences flanked by direct repeats in the 3' untranslated region.

Gene names and symbols associated with CYP1A2

  • cytochrome P450 1A2 (VDBG_06455) antibody
  • cytochrome P450 1A2 (CYP1A2) antibody
  • cytochrome P450 1A2-like (LOC101825565) antibody
  • cytochrome P450 LM4 (LOC100328937) antibody
  • cytochrome P450, family 1, subfamily A, polypeptide 2 (CYP1A2) antibody
  • cytochrome P450, family 1, subfamily a, polypeptide 2 (Cyp1a2) antibody
  • CP12 antibody
  • CP450 antibody
  • CYP-IA2 antibody
  • Cyp1a1 antibody
  • CYP1A2 antibody
  • CYPD45 antibody
  • CYPIA-2 antibody
  • CYPIA2 antibody
  • P-450d antibody
  • P3-450 antibody
  • P450(PA) antibody
  • P450-3 antibody
  • P450-PM4 antibody
  • RATCYPD45 antibody

Protein level used designations for CYP1A2

cytochrome P450 1A2 , CYPIA2 , Cytochrome P450-MC4 , Hepatic cytochrome P-450MC1 , cytochrome P-450 form 4 , cytochrome P-450IA2 , pulmonary cytochrome P-450MC1 , P450 LM4 , P450 isozyme 4 , cytochrome P450 isozyme 4 , cytochrome P450-PM4 , P450 form 4 , aryl hydrocarbon hydroxylase , cytochrome P(3)450 , cytochrome P450 4 , cytochrome P450, subfamily I (aromatic compound-inducible), polypeptide 2 , cytochrome P450-P3 , dioxin-inducible P3-450 , flavoprotein-linked monooxygenase , microsomal monooxygenase , xenobiotic monooxygenase , aromatic compound inducible , cytochrome P450 family 1 subfamily a polypeptide 1 , cytochrome P450, 1a2, aromatic compound inducible , cytochrome P450-P2 , Cytochrome P450 subfamily I (aromatic compound-inducible) member A2 (Q42 form d) , P-448 , P450-D , cytochrome P-448 , cytochrome P-450d , cytochrome P450, 1a2 , cytochrome P450, subfamily I (aromatic compound-inducible), member A2 (Q42, form d) , cytochrome P450-D

GENE ID SPECIES
9536166 Verticillium alfalfae VaMs.102
554345 Felis catus
101825565 Mesocricetus auratus
100328937 Oryctolagus cuniculus
1544 Homo sapiens
13077 Mus musculus
24297 Rattus norvegicus
414856 Gallus gallus
494010 Canis lupus familiaris
100135513 Cavia porcellus
100152910 Sus scrofa
100172368 Pongo abelii
100392712 Callithrix jacchus
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