anti-Endoglin (ENG) Antibodies

ENG encodes a homodimeric transmembrane protein which is a major glycoprotein of the vascular endothelium. Additionally we are shipping Endoglin Kits (58) and Endoglin Proteins (50) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
ENG 2022 P17813
ENG 13805 Q63961
ENG 497010  
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Top anti-Endoglin Antibodies at antibodies-online.com

Showing 10 out of 755 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Guinea Pig Rabbit Un-conjugated IHC, WB WB Suggested Anti-ENG Antibody Titration: 2.0ug/mlPositive Control: HepG2 cell lysate 100 μL Log in to see 2 to 3 Days
$229.00
Details
Human Rabbit Un-conjugated FACS, IF (p), IHC (p), WB Formalin-fixed and paraffin embedded human gastric carcinoma labeled with Anti-CD105 Polyclonal Antibody (ABIN670401), Unconjugated at 1:200, followed by conjugation to the secondary antibody and DAB staining Formalin-fixed and paraffin embedded human placenta tissue labeled with Anti-CD105 Polyclonal Antibody, Unconjugated at 1:200, followed by conjugation to the secondary antibody and DAB staining 100 μL Log in to see 3 to 7 Days
$307.45
Details
Human Rabbit Un-conjugated FACS, IF (cc), IF (p), IHC (p), WB Formalin-fixed and paraffin embedded rat pancreas tissue labeled with Anti-CD105 Polyclonal Antibody, unconjugated(ABIN707561) at 1: 200 followed by incubation with conjugated secondary antibody and DAB staining Formalin-fixed and paraffin embedded rat pancreas tissue labeled with Anti-CD105 Polyclonal Antibody (ABIN707561), Unconjugated at 1:200 followed by conjugation to the secondary antibody, (SP-0023), and DAB staining 100 μL Log in to see 3 to 7 Days
$307.45
Details
Human Rabbit Un-conjugated FACS, IHC (p), WB Western blot analysis of CD105 antibody (Center E395) (ABIN389408) in mouse heart tissue lysates (35 µg/lane). CD105 (arrow) was detected using the purified polyclonal antibody. Flow cytometric analysis of NCI-H292 cells using CD105 Antibody (Center E395)(bottom histogram) compared to a negative control cell (top histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated EIA, WB Western blot analysis of ENG (arrow) using CD105 / Endoglin  Antibody . 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the ENG gene. 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Horse Mouse FITC FACS Staining of KG1 cells with MOUSE ANTI HUMAN CD105:FITC (ABIN118831). 0.1 mg Log in to see 6 to 8 Days
$423.50
Details
Horse Mouse PE FACS Staining of KG1 cells with mouse anti human CD105 PE (ABIN118833). 100 Tests Log in to see 6 to 8 Days
$467.50
Details
Horse Mouse Un-conjugated FACS, IHC (fro), IP, WB Staining of KG1 cells with Mouse Anti Human CD105 (ABIN118832). 0.2 mg Log in to see 6 to 8 Days
$500.50
Details
Human Mouse Fluorescein FACS Detection of Endoglin/CD105 in U937 Human Cell Line by Flow Cytometry. U937 human histiocytic lymphoma cell line was stained with Mouse Anti-Human Endoglin/CD105 Fluorescein-conjugated Monoclonal Antibody. Detection of Endoglin/CD105 in U937 Human Cell Line by Flow Cytometry. U937 human histiocytic lymphoma cell line was stained with Mouse Anti-Human Endoglin/CD105 Fluorescein-conjugated Monoclonal Antibody. 25 Tests Log in to see 8 to 9 Days
$134.40
Details
Mouse Rat Fluorescein FACS Detection of Endoglin/CD105 in MS-1 Mouse Cell Line by Flow Cytometry. MS-1 mouse pancreatic islet endothelial cell line was stained with Rat Anti-Mouse Endoglin/CD105 Fluorescein-conjugated Monoclonal Antibody. Detection of Endoglin/CD105 in MS-1 Mouse Cell Line by Flow Cytometry. MS-1 mouse pancreatic islet endothelial cell line was stained with Rat Anti-Mouse Endoglin/CD105 Fluorescein-conjugated Monoclonal Antibody. 25 Tests Log in to see 8 to 9 Days
$147.00
Details

ENG Antibodies by Reactivity, Application, Clonality and Conjugate

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Top referenced anti-Endoglin Antibodies

  1. Human Polyclonal ENG Primary Antibody for FACS, IF (cc) - ABIN707561 : Zhao, Yin, Guo, Wang, Wang, Chen: Placental expression of VEGF is increased in pregnancies with hydatidiform mole: possible association with developing very early onset preeclampsia. in Early human development 2013 (PubMed)
    Show all 8 references for 707561

  2. Human Monoclonal ENG Primary Antibody for FACS - ABIN4896992 : Narcisi, Cleary, Brama, Hoogduijn, Tüysüz, ten Berge, van Osch: Long-term expansion, enhanced chondrogenic potential, and suppression of endochondral ossification of adult human MSCs via WNT signaling modulation. in Stem cell reports 2015 (PubMed)
    Show all 7 references for 4896992

  3. Human Polyclonal ENG Primary Antibody for FACS, IF (p) - ABIN670401 : Boopathy, Pendergrass, Che, Yoon, Davis: Oxidative stress-induced Notch1 signaling promotes cardiogenic gene expression in mesenchymal stem cells. in Stem cell research & therapy 2014 (PubMed)
    Show all 4 references for 670401

  4. Horse (Equine) Monoclonal ENG Primary Antibody for FACS - ABIN118831 : Haruta, Seon: Distinct human leukemia-associated cell surface glycoprotein GP160 defined by monoclonal antibody SN6. in Proceedings of the National Academy of Sciences of the United States of America 1986 (PubMed)
    Show all 3 references for 118831

  5. Mouse (Murine) Monoclonal ENG Primary Antibody for FACS - ABIN4896370 : Madhu, Li, Dighe, Balian, Cui et al.: BMP-non-responsive Sca1+ CD73+ CD44+ mouse bone marrow derived osteoprogenitor cells respond to combination of VEGF and BMP-6 to display enhanced osteoblastic differentiation and ectopic bone ... in PLoS ONE 2014 (PubMed)
    Show all 3 references for 4896370

  6. Human Polyclonal ENG Primary Antibody for EIA, WB - ABIN951149 : Ríus, Smith, Almendro, Langa, Botella, Marchuk, Vary, Bernabéu: Cloning of the promoter region of human endoglin, the target gene for hereditary hemorrhagic telangiectasia type 1. in Blood 1999 (PubMed)
    Show all 2 references for 951149

  7. Guinea Pig Polyclonal ENG Primary Antibody for IHC, WB - ABIN2777735 : Sanz-Rodriguez, Guerrero-Esteo, Botella, Banville, Vary, Bernabéu: Endoglin regulates cytoskeletal organization through binding to ZRP-1, a member of the Lim family of proteins. in The Journal of biological chemistry 2004 (PubMed)

More Antibodies against Endoglin Interaction Partners

Human Endoglin (ENG) interaction partners

  1. Several germline variants in Hamartomatous Polyposis Syndrome genes were detected, among them three in ENG, two in BMPR1A (show BMPR1A Antibodies), one in PTEN (show PTEN Antibodies), and one in SMAD4 (show SMAD4 Antibodies). Although some of the detected variants have been reported previously none could be definitely pathogenic or likely pathogenic.

  2. 9q33.3q34.11 microdeletion including ENG gene identified in four patients with intellectual disability, epilepsy, nail (show CD244 Antibodies) dysplasia and bone malformations.

  3. Endoglin has an important role in VSMC recruitment and blood vessel maturation during angiogenesis.

  4. Soluble endoglin did not vary over the pregnancy course or between gestational hypertension, preeclampsia, and control groups.

  5. Serum and placental LXR-alpha (show NR1H3 Antibodies) and endoglin levels were significantly higher in patients with preeclampsia than those in control group (P<0.05, each).

  6. Our findings suggest a stronger chondrogenic potential of CD105(+) SMSCs in comparison to that of CD105(-) SMSCs and that CD105 enhances chondrogenesis of SMSCs by regulating TGF-beta (show TGFB1 Antibodies)/Smad2 (show SMAD2 Antibodies) signaling pathway, but not Smad1 (show GARS Antibodies)/5. Our study provides a better understanding of CD105 with respect to chondrogenic differentiation.

  7. The novel ENG c.-58G/A substitution in the Endoglin promoter co-segregates with Hereditary hemorrhagic telangiectasia symptoms in a family and appears to affect the transcriptional regulation of the gene, resulting in reduced Endoglin expression.

  8. sEng treatment resulted in an activation of NF-kappaB (show NFKB1 Antibodies), IL-6 (show IL6 Antibodies), suggesting activation of pro-inflammatory phenotype in endothelial cells.

  9. In adolescents with type 1 diabetes mellitus (T1DM), soluble endoglin concentrations might increase in parallel to the deterioration in endothelial function before subclinical structural vascular alterations.

  10. Akt (show AKT1 Antibodies) level was reduced in preeclamptic placentas relative to preterm control. Inhibition of PI3K (show PIK3CA Antibodies)/Akt (show AKT1 Antibodies) resulted in significantly elevated soluble endoglin release from endothelial cells, had no effect on MMP14 (show MMP14 Antibodies) mRNA expression but resulted in significantly reduced TIMP3 (show TIMP3 Antibodies). In contrast inhibiting PI3K (show PIK3CA Antibodies)/Akt (show AKT1 Antibodies) in placental explants or primary trophoblast did not change soluble endoglin release.

Mouse (Murine) Endoglin (ENG) interaction partners

  1. Endoglin controls blood vessel diameter through endothelial cell shape changes in response to haemodynamic cues.

  2. Endoglin prevents vascular malformation by regulating flow-induced cell migration and specification through VEGFR2 (show KDR Antibodies) signalling.

  3. Identification of novel regulators of developmental hematopoiesis using Endoglin regulatory elements as molecular probes

  4. Endoglin has an important role in VSMC recruitment and blood vessel maturation during angiogenesis.

  5. the TGFbeta1 (show TGFB1 Antibodies) coreceptor Eng selectively regulates expression of multiple transient receptor potential channels in the setting of left or right ventricular pressure overload

  6. Endothelial cell-specific endoglin expression in islets of Langerhans is sensitive to VEGF and plays partial roles in driving islet vascular development, however such regulation appears to be distinct to mechanisms required to modulate islet viability and size.

  7. Study provides evidence that the expression of endoglin is required for the establishment of uterine receptivity and the decidualization process, which mediate embryo adhesion or the attachment reaction.

  8. The changes in CD90 (show THY1 Antibodies) and CD105 expression in the testis and ovary of mice are reported.

  9. the altered immune activity of endoglin deficient macrophages could help to explain the higher rate of infectious diseases seen in HHT1 patients.

  10. These results demonstrate a requirement for endoglin in descendants of Pax3 (show PAX3 Antibodies)-expressing vascular cell precursors.

Endoglin (ENG) Antigen Profile

Protein Summary

This gene encodes a homodimeric transmembrane protein which is a major glycoprotein of the vascular endothelium. This protein is a component of the transforming growth factor beta receptor complex and it binds TGFB1 and TGFB3 with high affinity. Mutations in this gene cause hereditary hemorrhagic telangiectasia, also known as Osler-Rendu-Weber syndrome 1, an autosomal dominant multisystemic vascular dysplasia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with anti-Endoglin (ENG) Antibodies

  • endoglin (ENG) antibody
  • endoglin (LOC100226246) antibody
  • endoglin (Eng) antibody
  • AI528660 antibody
  • AI662476 antibody
  • CD105 antibody
  • DKFZp469D0419 antibody
  • END antibody
  • ENG antibody
  • HHT1 antibody
  • MGC137842 antibody
  • ORW1 antibody
  • S-endoglin antibody

Protein level used designations for anti-Endoglin (ENG) Antibodies

endoglin (Osler-Rendu-Weber syndrome 1) , endoglin , endoglin-like , CD105 antigen , cell surface MJ7/18 antigen , transmembrane glycoprotein

GENE ID SPECIES
609166 Canis lupus familiaris
615844 Bos taurus
741046 Pan troglodytes
771557 Gallus gallus
100173392 Pongo abelii
100226246 Taeniopygia guttata
100357448 Oryctolagus cuniculus
100387791 Callithrix jacchus
397096 Sus scrofa
2022 Homo sapiens
13805 Mus musculus
497010 Rattus norvegicus
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