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anti-Gap Junction Protein, beta 6, 30kDa (GJB6) Antibodies

Gap junctions allow the transport of ions and metabolites between the cytoplasm of adjacent cells. Additionally we are shipping GJB6 Kits (3) and GJB6 Proteins (3) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
GJB6 14623 P70689
GJB6 84403  
GJB6 10804 O95452
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Top anti-GJB6 Antibodies at antibodies-online.com

Showing 10 out of 48 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-GJB6 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:12500Positive Control: THP-1 cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated EIA, IHC (p), WB 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated IHC (p), WB Western blot analysis of GJB6 (arrow) using rabbit polyclonal GJB6 Antibody (N-term) (ABIN388377). 293 cell lysates (2 µg/lane) either nontransfected (Lane 1) or transiently transfected with the GJB6gene (Lane 2) (Origene Technologies). Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. BC = breast carcinoma. HC = hepatocarcinoma 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
$551.83
Details
Mouse Rabbit Un-conjugated IHC (fro), ELISA, WB   50 μg Log in to see 8 to 10 Days
$742.50
Details
Human Rabbit Un-conjugated WB GJB6 antibody used at 1 ug/ml to detect target protein. 50 μg Log in to see 3 to 4 Days
$473.93
Details
Human Goat Un-conjugated ELISA, WB   0.1 mg Log in to see 2 to 3 Days
$433.13
Details
Human Rabbit Biotin IHC, ELISA, WB   200 μL Log in to see 8 to 10 Days
$969.83
Details
Human Goat Un-conjugated ELISA, WB   100 μg Log in to see 4 to 5 Days
$221.76
Details
Human Goat Un-conjugated ELISA   100 μg Log in to see 8 to 10 Days
$419.83
Details

GJB6 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Mouse (Murine) ,
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Rat (Rattus) ,
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Human ,
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Top referenced anti-GJB6 Antibodies

  1. Human Polyclonal GJB6 Primary Antibody for EIA, IHC (p) - ABIN357095 : Beltramello, Bicego, Piazza, Ciubotaru, Mammano, DAndrea: Permeability and gating properties of human connexins 26 and 30 expressed in HeLa cells. in Biochemical and biophysical research communications 2003 (PubMed)
    Show all 2 references for ABIN357095

  2. Cow (Bovine) Polyclonal GJB6 Primary Antibody for WB - ABIN2774862 : BuSaba, Cunningham: Connexin 26 and 30 genes mutations in patients with chronic rhinosinusitis. in The Laryngoscope 2008 (PubMed)

More Antibodies against GJB6 Interaction Partners

Mouse (Murine) Gap Junction Protein, beta 6, 30kDa (GJB6) interaction partners

  1. Connexin 30, but not connexin 43 (show GJA1 Antibodies), hemichannels close upon protein kinase C (show PKC Antibodies) activation, illustrating that connexin hemichannels display not only isoform-specific permeability profiles but also isoform-specific regulation by protein kinase C (show PKC Antibodies).

  2. presence of Cx30 in the cochlea does not compensate for Cx26 (show GJB2 Antibodies) loss, and the absence of both connexins from vestibular sensory epithelia is no more injurious than the absence of one of them

  3. four unique Cx30 mutants might cause disease through different mechanisms that also likely include their selective trans-dominant effects on coexpressed connexins.

  4. The cortex modafinil injection increases the expression of mRNA and protein of connexin 30.

  5. Our data reveal that Cx43 (show GJA1 Antibodies) promotes the survival of newborn neurons in the adult mouse hippocampus whereas Cx30 restricts their survival.

  6. The observations demonstrate a role for Cx30 and intercellular communication in regulating repair responses in an epithelial tissue.

  7. We showed co-expression of Cx30 and p63 (show CKAP4 Antibodies) in developing mouse hair follicles and nail (show CD244 Antibodies) units.

  8. in the Cx30 knock-out mouse model, defective Cx26 (show GJB2 Antibodies) expression is the likely cause of deafness, and in contrast to current opinion, Cx30 is dispensable for cochlear functions

  9. These results demonstrate that astroglial connexins are necessary to maintain BBB (show ALMS1 Antibodies) integrity.

  10. This study demonistrated that Cx30/Cx47 (show GJC2 Antibodies) double-deficient mice has the functional role of both connexins for interastrocytic, interoligodendrocytic, and panglial coupling, and show that both connexins are required for maintenance of myelin.

Human Gap Junction Protein, beta 6, 30kDa (GJB6) interaction partners

  1. identification and functional characterization of a new Cx30 mutation in a family with hearing impairment in association with previously unreported skin anomalies

  2. Screening of GJB6 gene large deletions among Syrians with congenital hearing impairment.

  3. Periostin (show POSTN Antibodies) is a robust marker of glioma malignancy and potential tumor recurrence. Abrogation of glioma stem cell tumorigenicity after periostin (show POSTN Antibodies) inhibition provides support for exploring the therapeutic impact of targeting periostin (show POSTN Antibodies).

  4. results suggest that SNPs present in the GJB2 (show GJB2 Antibodies) and GJB6 genes may have an influence on ARNSHL in humans.

  5. found that connexin 26 (Cx26 (show GJB2 Antibodies)) and Cx30 GJs readily diffuse within the plaque structures, whereas Cx43 (show GJA1 Antibodies) GJs remain persistently immobile for more than 2 min after bleaching

  6. GJB6 deletions were not detected.

  7. An absence of GJB6 mutations and low frequency of SLC26A4 (show SLC26A4 Antibodies) mutations suggest that additional genetic factors may contribute to nonsyndromic hearing loss in India.

  8. Results show high mRNA and protein levels for Cx43 (show GJA1 Antibodies) and Cx30 in breast cancer but they are correlated with improved and bad outcome respectively suggesting that they may serve as prognostic markers in breast cancer.

  9. Mutations in GJB2 (show GJB2 Antibodies), GJB6 and GJA1 (show GJA1 Antibodies) are not a major cause of non-syndromic deafness in black Africans

  10. study found A c.31G>A (p.G11R) missense mutation in GJB6 gene is the genotypic characteristic for hidrotic ectodermal dysplasia in Chinese population

GJB6 Antigen Profile

Protein Summary

Gap junctions allow the transport of ions and metabolites between the cytoplasm of adjacent cells. They are formed by two hemichannels, made up of six connexin proteins assembled in groups. Each connexin protein has four transmembrane segments, two extracellular loops, a cytoplasmic loop formed between the two inner transmembrane segments, and the N- and C-terminus both being in the cytoplasm. The specificity of the gap junction is determined by which connexin proteins comprise the hemichannel. In the past, connexin protein names were based on their molecular weight, however the new nomenclature uses sequential numbers based on which form (alpha or beta) of the gap junction is present. This gene encodes one of the connexin proteins. Mutations in this gene have been found in some forms of deafness and in some families with hidrotic ectodermal dysplasia.

Gene names and symbols associated with GJB6

  • connexin 30 (LOC387566) antibody
  • gap junction protein, beta 2, 26kDa (gjb2) antibody
  • gap junction protein, beta 6, 30kDa (GJB6) antibody
  • gap junction protein, beta 6 (Gjb6) antibody
  • AA958971 antibody
  • connexin-26 antibody
  • cx26 antibody
  • CX30 antibody
  • CX31 antibody
  • D14Bwg0506e antibody
  • DFNA3 antibody
  • dfna3a antibody
  • DFNA3B antibody
  • dfnb1 antibody
  • dfnb1a antibody
  • DFNB1B antibody
  • ECTD2 antibody
  • ED2 antibody
  • EDH antibody
  • gjb6 antibody
  • HED antibody
  • HED2 antibody
  • nsrd1 antibody
  • ppk antibody

Protein level used designations for GJB6

connexin 30 , connexin 26 , gap junction beta-2 protein , gap junction protein, beta 6, 30kDa , connexin-30 , gap junction beta-6 protein , gap junction membrane channel protein beta 6 , gap junction protein, beta 6 (connexin 30) , ectodermal dysplasia 2, hidrotic (Clouston syndrome) , connexin 31 , connexin-31

GENE ID SPECIES
387566 Xenopus laevis
549738 Xenopus (Silurana) tropicalis
704105 Macaca mulatta
14623 Mus musculus
84403 Rattus norvegicus
10804 Homo sapiens
508454 Bos taurus
395771 Gallus gallus
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