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anti-Glutamate Receptor, Metabotropic 5 (GRM5) Antibodies

L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Additionally we are shipping Metabotropic Glutamate Receptor 5 Kits (20) and Metabotropic Glutamate Receptor 5 Proteins (7) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
GRM5 2915 P41594
GRM5 24418 P31424
GRM5 108071 Q3UVX5
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Top anti-Metabotropic Glutamate Receptor 5 Antibodies at antibodies-online.com

Showing 10 out of 138 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated WB Western blot analysis of Metabotropic Glutamate Receptor 5 (GPRC1E) antibody (C-term T1003) (ABIN390320) in mouse brain tissue lysates (35 µg/lane). Metabotropic Glutamate Receptor 5 (arrow) was detected using the purified polyclonal antibody. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated EIA, WB Western blot analysis of Metabotropic Glutamate Receptor 5 (GPRC1E) antibody (C-term) in mouse brain tissue lysates (35ug/lane). Metabotropic Glutamate Receptor 5 (arrow) was detected using the purified Pab. 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Dog Rabbit Un-conjugated IHC (fro), IF, WB mGluR5 antibody staining of Rat globus pallidus. Images courtesy of Dr. Joyce Besheer, UNC. 50 μg Log in to see 6 to 8 Days
$709.50
Details
Human Mouse Un-conjugated IP, IHC, WB Western Blotting rat brain membrane mGluR1 5 1 in 1000. 100 μg Log in to see 3 to 4 Days
$383.90
Details
Mouse Rabbit Un-conjugated ICC, IHC, WB Western blot analysis of rat brain membranes: 1. Anti-mGluR5 (extracellular) antibody, (1:500). 2. Anti-mGluR5 (extracellular) antibody, preincubated with the control peptide antigen. Expression of mGluR5 in rat cerebellum and hippocampus Immunohistochemical staining of perfusion-fixed frozen rat cerebellum sections using Anti-mGluR5 (extracellular) antibody, (1:50). mGluR5 (red) was detected in cerebellar Purkinje cells (vertical arrows) and in the molecular layer (horizontal arrows). Staining with mouse anti-parvalbumin (green) revealed co-localization in Purkinje but not in the molecular layer. Little staining of mGluR5 was detected in the granule layer. DAPI counterstain is used to visualize nuclei of all cells (blue). 50 μL Log in to see 10 to 11 Days
$678.57
Details
Human Rabbit Un-conjugated IHC (p) 7 mL Log in to see 2 to 3 Days
$205.00
Details
Human Rabbit Un-conjugated IF, ELISA, WB Western blot analysis of extracts from HT-29 cells, using GRM5 Antibody. The lane on the right is treated with the synthesized peptide. Immunofluorescence analysis of LOVO cells, using GRM5 Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Rabbit Un-conjugated IHC (p) 50 μg Log in to see 6 to 8 Days
$500.50
Details
Human Rabbit Un-conjugated EIA, IF, IHC (p), WB 0.1 mg Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated IHC (p), WB Anti-GRM5 / MGLUR5 antibody  ABIN1048937 IHC staining of human brain, neurons and glia. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. 50 μg Log in to see 8 to 10 Days
$451.00
Details

GRM5 Antibodies by Reactivity, Application, Clonality and Conjugate

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Top referenced anti-Metabotropic Glutamate Receptor 5 Antibodies

  1. Human Polyclonal Metabotropic Glutamate Receptor 5 Primary Antibody for EIA, WB - ABIN358930 : Pacheco, Ciruela, Casadó, Mallol, Gallart, Lluis, Franco: Group I metabotropic glutamate receptors mediate a dual role of glutamate in T cell activation. in The Journal of biological chemistry 2004 (PubMed)
    Show all 5 references for ABIN358930

  2. Human Polyclonal Metabotropic Glutamate Receptor 5 Primary Antibody for WB - ABIN390320 : Corti, Clarkson, Crepaldi, Sala, Xuereb, Ferraguti: Gene structure of the human metabotropic glutamate receptor 5 and functional analysis of its multiple promoters in neuroblastoma and astroglioma cells. in The Journal of biological chemistry 2003 (PubMed)
    Show all 3 references for ABIN390320

  3. Dog (Canine) Polyclonal Metabotropic Glutamate Receptor 5 Primary Antibody for IHC (fro), IF - ABIN783986 : Francesconi, Kumari, Zukin: Regulation of group I metabotropic glutamate receptor trafficking and signaling by the caveolar/lipid raft pathway. in The Journal of neuroscience : the official journal of the Society for Neuroscience 2009 (PubMed)
    Show all 2 references for ABIN783986

  4. Mouse (Murine) Polyclonal Metabotropic Glutamate Receptor 5 Primary Antibody for ICC, IHC - ABIN1742080 : Ferraguti, Shigemoto: Metabotropic glutamate receptors. in Cell and tissue research 2006 (PubMed)

  5. Human Monoclonal Metabotropic Glutamate Receptor 5 Primary Antibody for IP, IHC - ABIN1027721 : Keinänen, Wisden, Sommer, Werner, Herb, Verdoorn, Sakmann, Seeburg: A family of AMPA-selective glutamate receptors. in Science (New York, N.Y.) 1990 (PubMed)

More Antibodies against Metabotropic Glutamate Receptor 5 Interaction Partners

Human Glutamate Receptor, Metabotropic 5 (GRM5) interaction partners

  1. Decrease of mGluR5 receptor density goes parallel with changes in enkephalin and substance P (show TAC1 Antibodies) immunoreactivity in Huntington's disease

  2. The metabotropic glutamate (show GRIN1 Antibodies) receptor subtype 5 (mGluR5) has been implicated in the pathophysiology of mood and anxiety disorders.

  3. The interaction between GRM5 and cellular prion protein (show PRNP Antibodies) has a central role in transgenic mouse model of Alzheimer's disease pathogenesis.

  4. Data suggest that metabotropic glutamate receptors recycling is completely dependent on the activity of PP2A whereas, PP2B has partial effect on this process.

  5. findings provide evidence for decreased expression of metabotropic glutamate receptor 5 and its signaling components representing a key pathophysiological hallmark in autism spectrum disorder.

  6. Study provided evidence that protein expression of mGluR5 is significantly higher (total: 42%; monomer: 25%; dimer: 52%) in the hippocampal CA1 (show CA1 Antibodies) region of schizophrenia subjects relative to healthy controls

  7. Results provide compelling evidence that mGluR5 regulation is altered in schizophrenia, likely contributing to the altered glutamatergic signaling that is associated with the disorder

  8. This review supports altered mGluR5 functioning as a convergent point in ASD (show ARSD Antibodies) pathogenesis and indicates more research is warranted into mGluR5 as a potential therapeutic target.

  9. both an increased and reduced mGlu5 functioning seem to be associated with Intellectual Disability and autism spectrum disorders.

  10. Findings suggest that mGluR2 (show GRM2 Antibodies)/3 and mGluR5s are unaltered in the anterior cingulate cortex in psychotic and nonpsychotic depression, bipolar disorder and schizophrenia

Mouse (Murine) Glutamate Receptor, Metabotropic 5 (GRM5) interaction partners

  1. Dysregulation of fragile X mental retardation protein (show NUFIP2 Antibodies)-metabotropic glutamate receptor 5 signaling pathway, accompanied with a downregulation of GABA(A) receptor beta3 subunit expression, may contribute to the 'autistic-like' features knockout mice.

  2. Our findings suggest a fundamental role for mGluR5 in the development of Pv(+) neurons and show that alterations in this system can produce broad-spectrum alterations in brain network activity

  3. This work provides strong evidence that Homer (show HOMER1 Antibodies)-mGlu5 binding contributes to symptoms associated with neurodevelopmental disorders

  4. This study identify highly specialized roles of lateral septal mGluR5 and Oxtr (show OXTR Antibodies) in the the regulation of discrete social behaviors, and suggest that deficits in social interactions.

  5. Results offer the first evidence that changes in the striatal expression of mGlu4 (show GRM4 Antibodies) and mGlu5 receptors occur in acute models of parkinsonisms

  6. We show for the first time that knockdown of mGlu5 in the dorsal hippocampus is sufficient to impair spatial learning in Morris Water Maze

  7. The results of this study demonstrated an important role for mGlu5 in environmental modulation of schizophrenia-related behavioral impairments.

  8. chronic postnatal down-regulation of mGluR5 signaling produces coordinated impairments in both NMDAR (show GRIN1 Antibodies)-dependent LTD in vitro and ocular dominance plasticity in vivo.

  9. mGluR5 blockage elicits distinct outcomes in terms of locomotor activity and motor coordination depending on the brain region injected with mGluR5 antagonist.

  10. Results provide compelling evidence for the involvement of the Homer1 (show HOMER1 Antibodies)/mGluR5 complex in the emergence and regulation of stress-induced behavioral and neuroendocrine phenotypes

Metabotropic Glutamate Receptor 5 (GRM5) Antigen Profile

Protein Summary

L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors, that have been divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and GRM5 and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3 while Group III includes GRM4, GRM6, GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with GRM5

  • glutamate receptor, metabotropic 5 (GRM5) antibody
  • glutamate receptor, metabotropic 5 (Grm5) antibody
  • 6430542K11Rik antibody
  • AI850523 antibody
  • Glu5R antibody
  • Gprc1e antibody
  • mGlu5 antibody
  • mGlur5 antibody
  • mGluR5b antibody

Protein level used designations for GRM5

metabotropic glutamate receptor 5 , metabotropic glutamate receptor 5 variant F , metabotropic glutamate receptor 5 variant G , metabotropic glutamate receptor 5 variant H , metabotropic glutamate receptor (mGluR5) , metabotropic glutamate receptor 5b , G protein coupled receptor, family C, group 1, member E , G protein-coupled receptor GRM5 , G protein-coupled receptor, family C, group 1, member E , metabotropic glutamate receptor subtype 5b , metabotropic glutamate receptor type 5

GENE ID SPECIES
373933 Gallus gallus
2915 Homo sapiens
24418 Rattus norvegicus
108071 Mus musculus
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