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Interleukin 26 Proteins (IL26)

May play a role in local mechanisms of mucosal immunity and seems to have a proinflammatory function. Additionally we are shipping IL26 Antibodies (29) and IL26 Kits (10) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
IL26 55801 Q9NPH9
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Top IL26 Proteins at antibodies-online.com

Showing 2 out of 3 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 2 μg Log in to see 9 Days
$333.33
Details

IL26 Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,
,

More Proteins for Interleukin 26 (IL26) Interaction Partners

Human Interleukin 26 (IL26) interaction partners

  1. IL-26 is emerging as a potentially important player in host defense and may also be a pathogenic factor in the chronic inflammatory disorders of humans. [Review]

  2. The negative influence of IL-26 on the anti-mycobacterial activity and its constitutive presence in both serum and monocyte supernatants prompt a proposal that IL26 as a candidate gene for tuberculosis susceptibility.

  3. IL-26 differentially modulates the infection by different enveloped viruses.

  4. Elevated levels of IL-26 in human gastric cancer promote proliferation and survival by modulating STAT1 (show STAT1 Proteins)/STAT3 (show STAT3 Proteins) signaling.

  5. IL-26 appears as a novel proinflammatory cytokine, located upstream of the proinflammatory cascade, that may constitute a promising target to treat rheumatoid arthritis and chronic inflammatory disorders.

  6. Identify a second enhancer element positioned between IL26 and IFNG required for both IL26 and IFNG expression. One function of this enhancer is to facilitate recruitment of RNA polymerase II to promoters of both genes.

  7. common polymorphisms in the IFNgamma/IL-26 gene region may contribute to sex bias in susceptibility to rheumatoid arthritis, by distorting the propensity of female carriers versus male carriers to contract this disease.

  8. The active receptor complex for IL-26 is a heterodimer composed of two receptor proteins: IL-20 (show IL20 Proteins) receptor 1 and IL-10 (show IL10 Proteins) receptor 2. Signaling through the IL-26 receptor results in activation of STAT1 (show STAT1 Proteins) and STAT3 (show STAT3 Proteins).

  9. sensitivity to recombinant interleukin-26(IL-26) of various cell lines strictly correlated with the expression of IL-20 (show IL20 Proteins) receptor 1 and blocking antibodies against either IL-10 (show IL10 Proteins) receptor 2 or IL-20 (show IL20 Proteins) receptor 1 inhibited IL-26-dependent signal transduction

Zebrafish Interleukin 26 (IL26) interaction partners

  1. Expression analysis of IL-22 (show IL22 Proteins), IL-26 and two IFN-gamma (show IFNG Proteins) genes suggests an active role of these genes in immune responses in fish.

IL26 Protein Profile

Protein Summary

May play a role in local mechanisms of mucosal immunity and seems to have a proinflammatory function. May play a role in inflammatory bowel disease. Activates STAT1 and STAT3, MAPK1/3 (ERK1/2), JUN and AKT. Induces expression of SOCS3, TNF-alpha and IL-8, secretion of IL-8 and IL-10 and surface expression of ICAM1. Decreases proliferation of intestinal epithelial cells. Is inhibited by heparin.

Gene names and symbols associated with Interleukin 26 Proteins (IL26)

  • interleukin 26 (IL26)
  • interleukin 26 (il26)
  • interleukin 26 (LOC100037932)
  • interleukin 26 (LOC100348730)
  • AK155 protein
  • IL-26 protein
  • IL26 protein
  • zgc:194942 protein

Protein level used designations for Interleukin 26 Proteins (IL26)

interleukin-26 , Ifnphi5 , interleukin 26

GENE ID SPECIES
55801 Homo sapiens
553971 Danio rerio
608923 Canis lupus familiaris
718027 Macaca mulatta
741377 Pan troglodytes
782075 Bos taurus
100037932 Sus scrofa
100348730 Oryctolagus cuniculus
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