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MAP1A and MAP1B are microtubule-associated proteins which mediate the physical interactions between microtubules and components of the cytoskeleton. Additionally we are shipping Microtubule-Associated Protein 1 Light Chain 3 alpha Proteins (15) and Microtubule-Associated Protein 1 Light Chain 3 alpha Kits (11) and many more products for this protein.
Showing 10 out of 289 products:
Human Polyclonal MAP1LC3A Primary Antibody for ICC, IF - ABIN388483
Sivridis, Koukourakis, Zois, Ledaki, Ferguson, Harris, Gatter, Giatromanolaki: LC3A-positive light microscopy detected patterns of autophagy and prognosis in operable breast carcinomas. in The American journal of pathology 2010
Show all 31 references for ABIN388483
Human Polyclonal MAP1LC3A Primary Antibody for EIA, IF - ABIN1449594
Chen, Azad, Gibson: Superoxide is the major reactive oxygen species regulating autophagy. in Cell death and differentiation 2009
Show all 15 references for ABIN1449594
Human Polyclonal MAP1LC3A Primary Antibody for EIA, WB - ABIN1449593
Zheng, Liu, Li, Xu, Xu: RNA interference-mediated downregulation of Beclin1 attenuates cerebral ischemic injury in rats. in Acta pharmacologica Sinica 2009
Show all 9 references for ABIN1449593
Human Polyclonal MAP1LC3A Primary Antibody for DB, EIA - ABIN1449623
Su, Chao, Huang, Weng, Jeng, Lai: Rab5 and class III phosphoinositide 3-kinase Vps34 are involved in hepatitis C virus NS4B-induced autophagy. in Journal of virology 2011
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Human Polyclonal MAP1LC3A Primary Antibody for DB - ABIN1881524
Scherz-Shouval, Weidberg, Gonen, Wilder, Elazar, Oren: p53-dependent regulation of autophagy protein LC3 supports cancer cell survival under prolonged starvation. in Proceedings of the National Academy of Sciences of the United States of America 2010
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Human Polyclonal MAP1LC3A Primary Antibody for EIA, IF - ABIN1449600
Giatromanolaki, Koukourakis, Harris, Polychronidis, Gatter, Sivridis: Prognostic relevance of light chain 3 (LC3A) autophagy patterns in colorectal adenocarcinomas. in Journal of clinical pathology 2010
Show all 3 references for ABIN1449600
Human Polyclonal MAP1LC3A Primary Antibody for EIA, IF - ABIN1449597
Tanida, Sou, Ezaki, Minematsu-Ikeguchi, Ueno, Kominami: HsAtg4B/HsApg4B/autophagin-1 cleaves the carboxyl termini of three human Atg8 homologues and delipidates microtubule-associated protein light chain 3- and GABAA receptor-associated protein-phospholipid conjugates. in The Journal of biological chemistry 2004
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Human Monoclonal MAP1LC3A Primary Antibody for EIA, IF - ABIN1449372
Rouschop, van den Beucken, Dubois, Niessen, Bussink, Savelkouls, Keulers, Mujcic, Landuyt, Voncken, Lambin, van der Kogel, Koritzinsky, Wouters: The unfolded protein response protects human tumor cells during hypoxia through regulation of the autophagy genes MAP1LC3B and ATG5. in The Journal of clinical investigation 2010
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Human Polyclonal MAP1LC3A Primary Antibody for IF, WB - ABIN319367
Hammarback, Obar, Hughes, Vallee: MAP1B is encoded as a polyprotein that is processed to form a complex N-terminal microtubule-binding domain. in Neuron 1991
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Chicken Polyclonal MAP1LC3A Primary Antibody for WB - ABIN2784522
Taylor, Kirkegaard: Modification of cellular autophagy protein LC3 by poliovirus. in Journal of virology 2007
Up-regulation of LC3 is associated with carcinogenesis and progression of Salivary Adenoid Cystic Carcinoma.
LC3 is exploited by coxsackievirus in both autophagy-dependent and -independent manners in vivo
Autophagy status, as determined by combined LC3, Beclin 1 and p62 expression, might be independently associated with poor survival in patients with gastric cancer.
Western blot and immunofluorescence validated antibody specificity, knockdown efficiency and autophagy induction prior to fixation in formalin and embedding in paraffin. LC3B and p62 antibodies were validated on cell pellets
FYCO1 (show FYCO1 Antibodies) requires a functional LC3A/B-preferring LC3-interacting Region (LIR (show CD300C Antibodies)) motif to facilitate efficient maturation of autophagosomes under basal conditions, whereas starvation-induced autophagy was unaffected
In colorectal cancer, differentiation degree and lymph node metastasis were associated with LC3 overexpression. LC3 expression was significantly higher in cancerous tissue than in adjacent tissue.
high nuclear HMGB1 (show HMGB1 Antibodies) levels and cytoplasmic HMGB1 (show HMGB1 Antibodies) expression predicted poor overall survival (OS) and disease-free survival (DFS (show FST Antibodies)). Meanwhile, high LC3 expression was associated with favorable prognosis.
These results demonstrate the essential role of BECN1 (show BECN1 Antibodies) in the functional formation of autophagosomes, but not in LC3B (show MAP1LC3B Antibodies) lipidation.
The authors show that LC3 is recruited specifically around secreting Shigella flexneri bacteria that are still present in vacuoles formed during entry and cell-to-cell spread.
Downregulation of beta 3 -integrin with cRGD peptide resulted in enhanced LC3-II and Beclin-1 (show BECN1 Antibodies) and decreased Bcl-2 (show BCL2 Antibodies) expression.
LC3 overexpression thus exerts neuroprotection through increasing alpha7nAChR expression for eAbeta binding and further enhancing autophagic activity for Abeta (show APP Antibodies) clearance in vitro and in vivo.
we describe basic protocols to measure the levels of endogenous LC3 and p62 by immunoblotting in cultured mammalian cells
Clusterin (show CLU Antibodies) facilitates stress-induced lipidation of LC3 and autophagosome biogenesis to enhance cancer cell survival.
Data indicate that Rubicon (Kiaa0226 (show KIAA0226 Antibodies)) and NOX2 (gp91phox (show CYBB Antibodies)) are involved in microtubule-associated protein (show SPAG5 Antibodies) LC3-associated phagocytosis.
starvation activates the autophagic PI3K, which in turn induces the recruitment of COPII to the endoplasmic reticulum-Golgi intermediate compartment to bud LC3 lipidation-active vesicles as one potential membrane source of the autophagosome.
With increasing age, the expression of LC3 in articular cartilage decreased.
In SOD1 (show SOD1 Antibodies) and Neurotomized mice the results of this studysuggest LC3, Fn14 (show TNFRSF12A Antibodies), Bcl3 (show BCL3 Antibodies) and Gadd45a (show GADD45A Antibodies) as candidate genes involved in the maintenance of the severe atrophic state.
Japanese encephalitis virus replication is negatively regulated by autophagy and occurs on LC3-I- and EDEM1 (show EDEM1 Antibodies)-containing membranes
Phosphorylation of LC3 by the STK3 (show PKN1 Antibodies) and STK4 is essential for autophagy.
Hedgehog (show SHH Antibodies) signaling is required for the Lc3 synthase (show B3GNT5 Antibodies) expression in embryonic lens
LC3 is localized in porcine oocytes during in vitro maturation.
Data suggest that expression of MAP1LC3A in graafian follicle/granulosa cell/theca cell is distinct in normal pigs versus miniature pigs; expression of MAP1LC3A is higher in normal pigs than in miniature pigs; MAP1LC3A may be marker of autophagy.
Data indicate that the expression of MAP1LC3A, B and autophagy-associated genes (ATG5 (show ATG5 Antibodies), mTOR (show FRAP1 Antibodies), Beclin-1 (show BECN1 Antibodies)) was increased in normal pigs, while decreased in miniature pigs.
MAP1A and MAP1B are microtubule-associated proteins which mediate the physical interactions between microtubules and components of the cytoskeleton. MAP1A and MAP1B each consist of a heavy chain subunit and multiple light chain subunits. The protein encoded by this gene is one of the light chain subunits and can associate with either MAP1A or MAP1B. Two transcript variants encoding different isoforms have been found for this gene. The expression of variant 1 is suppressed in many tumor cell lines, suggesting that may be involved in carcinogenesis.
microtubule-associated protein 1 light chain 3 alpha
, 35-alpha calcimedin
, Annexin III (Lipocortin III)
, lipocortin III
, placental anticoagulant protein III
, MAP1 light chain 3-like protein 1
, MAP1A/1B light chain 3 A
, MAP1A/MAP1B LC3 A
, MAP1A/MAP1B light chain 3 A
, autophagy-related ubiquitin-like modifier LC3 A
, microtubule-associated proteins 1A/1B light chain 3
, microtubule-associated proteins 1A/1B light chain 3A
, autophagy-related protein LC3 A
, microtubule-associated protein 1-light chain 3A
, microtubule-associated proteins 1A/1B light chain 3B
, UDP-GlcNAc:beta-Gal beta-1,3-N-acetylglucosaminyltransferase 5A
, UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5
, beta-1,3-N-acetylglucosaminyltransferase 5A
, lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase A
, lactotriaosylceramide synthase A
, lc(3)Cer synthase A
, lc3 synthase A