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anti-NLR Family, Pyrin Domain Containing 12 (NLRP12) Antibodies

NLRP12 encodes a member of the CATERPILLER family of cytoplasmic proteins. Additionally we are shipping NLRP12 Proteins (3) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
NLRP12 292541  
NLRP12 91662 P59046
NLRP12 378425  
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Top anti-NLRP12 Antibodies at antibodies-online.com

Showing 10 out of 105 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated IHC (p), WB NLRP12 Antibody (N-term) (ABIN657935) western blot analysis in human placenta tissue lysates (35 µg/lane). This demonstrates the NLRP12 antibody detected the NLRP12 protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated EIA, WB (LEFT) Western blot analysis of NLRP12 Antibody in HL-60 cell line lysates (35ug/lane). NLRP12 (arrow) was detected using the purified Pab. (RIGHT) Western blot analysis of NLRP12 Antibody in mouse testis tissue lysates (35ug/lane). NLRP12 (arrow) was detected using the purified Pab. 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated EIA, WB Western blot analysis of NALP12 in human brain tissue lysate with NALP12 antibody at 1 μg/ml. 0.1 mg Log in to see 6 to 8 Days
$401.50
Details
Mouse Mouse Un-conjugated WB NLRP12 antibody   western blot analysis in mouse cerebellum tissue lysates (35ug/lane).This demonstrates the NLRP12  antibody detected the NLRP12  protein (arrow). 0.1 mL Log in to see 10 to 11 Days
$324.50
Details
Mouse Mouse Un-conjugated WB NLRP12/MB10187 antibody  western blot analysis in mouse brain tissue lysates (35ug/lane).This demonstrates the NLRP12/MB10187 antibody detected the NLRP12/MB10187 protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Mouse Goat Un-conjugated ELISA, WB ABIN1686781 (1 µg/mL) staining of Mouse Spleen lysate (35 µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 100 μg Log in to see 4 to 5 Days
$318.20
Details
Human Rabbit Un-conjugated WB Western blot analysis of NLRP12 Antibody (ABIN652311) in HL-60 cell line lysates (35 µg/lane). NLRP12 (arrow) was detected using the purified polyclonal antibody. Western blot analysis of NLRP12 Antibody (ABIN652311) in mouse testis tissue lysates (35 µg/lane). NLRP12 (arrow) was detected using the purified polyclonal antibody. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Mouse Un-conjugated BCA 100 μg Log in to see 10 to 12 Days
$288.07
Details
Human Rabbit Alkaline Phosphatase (AP) ELISA, WB   200 μL Log in to see 8 to 10 Days
$969.83
Details
Human Rabbit Un-conjugated IHC (fro), IHC (p), IP, WB   50 μL Log in to see 8 to 10 Days
$507.83
Details

NLRP12 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-NLRP12 Antibodies

  1. Human Monoclonal NLRP12 Primary Antibody for BCA - ABIN2665297 : Allen: Non-Inflammasome Forming NLRs in Inflammation and Tumorigenesis. in Frontiers in immunology 2014 (PubMed)
    Show all 6 references for ABIN2665297

  2. Human Polyclonal NLRP12 Primary Antibody for EIA, WB - ABIN453767 : Ye, Lich, Moore, Duncan, Williams, Ting: ATP binding by monarch-1/NLRP12 is critical for its inhibitory function. in Molecular and cellular biology 2008 (PubMed)
    Show all 3 references for ABIN453767

  3. Human Polyclonal NLRP12 Primary Antibody for EIA, WB - ABIN783719 : Tschopp, Martinon, Burns: NALPs: a novel protein family involved in inflammation. in Nature reviews. Molecular cell biology 2003 (PubMed)
    Show all 2 references for ABIN783719

  4. Mouse (Murine) NLRP12 Primary Antibody for ELISA, WB - ABIN1686781 : Jéru, Duquesnoy, Fernandes-Alnemri, Cochet, Yu, Lackmy-Port-Lis, Grimprel, Landman-Parker, Hentgen, Marlin, McElreavey, Sarkisian, Grateau, Alnemri, Amselem: Mutations in NALP12 cause hereditary periodic fever syndromes. in Proceedings of the National Academy of Sciences of the United States of America 2008 (PubMed)

  5. Human Polyclonal NLRP12 Primary Antibody for IHC (p), WB - ABIN657935 : Cai, Batra, Del Piero, Jeyaseelan: NLRP12 modulates host defense through IL-17A-CXCL1 axis. in Mucosal immunology 2015 (PubMed)

More Antibodies against NLRP12 Interaction Partners

Human NLR Family, Pyrin Domain Containing 12 (NLRP12) interaction partners

  1. This process involved the upregulation of NLRP12.

  2. NLRX1 (show NLRX1 Antibodies), NLRP12 and NLRC3 (show NLRC3 Antibodies) negatively modulate the host immune response following virus exposure. (Review)

  3. Variants of NLRP12 were associated with common variable immunodeficiency.

  4. NLRP12/NLRP3 (show NLRP3 Antibodies)-dependent activation of caspase-1 (show CASP1 Antibodies) is likely to be a key event in mediating systemic production of IL-1beta (show IL1B Antibodies) and hypersensitivity to secondary bacterial infection during malaria.

  5. The genetics, expression and roles of NLRP12 in inflammatory signaling, host defense, and carcinogenes (show GUSB Antibodies)is are reviewed. Review.

  6. This study suggested that NLRP12 mutations might account for a small fraction of common variable immunodeficiency patients with severe auto-inflammatory complications.

  7. We will focus on NLRP6 (show NLRP6 Antibodies) and NLRP12.

  8. Letter: NLRP12 mutations associated with familial cold autoinflammatory syndrome 2 in Italian patients.

  9. Even with a variable range of associated manifestations, the extreme sensitivity to cold represents the main clinical hallmark in an individual carrying the p.D294E mutation of the NLRP12 gene.

  10. The authors report the first in vitro confirmed non-homotypic interaction between NLRP12 pyrin (show MEFV Antibodies) domain and the pro-apoptotic protein Fas-associated factor 1 (FAF-1 (show FAF1 Antibodies)), which links the innate immune system to apoptotic signaling.

Mouse (Murine) NLR Family, Pyrin Domain Containing 12 (NLRP12) interaction partners

  1. Nlrp12 deficiency caused increased neutrophil migration towards the chemokine (show CCL1 Antibodies) CXCL1 (show CXCL1 Antibodies) and the neutrophil parasite Leishmania major, revealing NLRP12 as a negative regulator of directed neutrophil migration under these conditions.

  2. modulation of NLRP12 levels controls alternative NF-kappaB (show NFKB1 Antibodies) signaling in OC precursors, altering bone homeostasis and osteolytic responses

  3. The absence of Nlrp12 results in an increased inflammatory response

  4. NLRP12 is an intrinsic negative regulator of T-cell-mediated immunity via altered NF-kappaB (show NFKB1 Antibodies) regulation and IL-4 (show IL4 Antibodies) production as key mediators of NLRP12-associated disease.

  5. NLRP12/NLRP3 (show NLRP3 Antibodies)-dependent activation of caspase-1 (show CASP1 Antibodies) is likely to be a key event in mediating systemic production of IL-1beta (show IL1B Antibodies) and hypersensitivity to secondary bacterial infection during malaria.

  6. The role of NLRP12 in NF-KB signaling, bacterial infections, colitis, colorectal tumorigenesis and gut (show GUSB Antibodies) homeostasis is studied in knockout mice. Review.

  7. NLRP12-deficient mice are highly resistant to S. typhimurium infection, which highlights the signaling pathway defined by NLRP12-mediated dampening of host immune defenses that could be exploited by S. typhimurium to persist and survive in the host

  8. NLRP12 does not significantly contribute to the in vivo host innate immune response to LPS (show TLR4 Antibodies) stimulation, Klebsiella pneumonia infection or Mycobacterium tuberculosis

  9. NLRP12 negatively regulated ERK (show EPHB2 Antibodies) and AKT (show AKT1 Antibodies) signaling pathways in affected tumor tissues.

  10. NLRP12 does not play a vital role in regulating Th2 driven airway inflammation using common model systems that are physiologically relevant to human disease.

NLRP12 Antigen Profile

Protein Summary

This gene encodes a member of the CATERPILLER family of cytoplasmic proteins. The encoded protein, which contains an N-terminal pyrin domain, a NACHT domain, a NACHT-associated domain, and a C-terminus leucine-rich repeat region, functions as an attenuating factor of inflammation by suppressing inflammatory responses in activated monocytes. Mutations in this gene cause familial cold autoinflammatory syndrome type 2. Alternative splicing results in multiple transcript variants.

Gene names and symbols associated with NLRP12

  • NLR family, pyrin domain containing 12 (Nlrp12) antibody
  • NLR family, pyrin domain containing 12 (NLRP12) antibody
  • CLR19.3 antibody
  • FCAS2 antibody
  • NALP12 antibody
  • PAN6 antibody
  • PYPAF7 antibody
  • RNO antibody
  • RNO2 antibody

Protein level used designations for NLRP12

NACHT, leucine rich repeat and PYD containing 12 , NLR family, pyrin domain containing 12 , PYRIN-containing APAF1-like protein 7 , NACHT, LRR and PYD domains-containing protein 12 , NLR family, pyrin domain containing 12, isoform 2 , monarch 1 , nucleotide-binding oligomerization domain, leucine rich repeat and pyrin domain containing 12 , regulated by nitric oxide , NACHT, LRR and PYD containing protein 12 , monarch-1

GENE ID SPECIES
292541 Rattus norvegicus
469002 Pan troglodytes
522018 Bos taurus
100018508 Monodelphis domestica
100063024 Equus caballus
100137561 Papio anubis
100352122 Oryctolagus cuniculus
100402104 Callithrix jacchus
100465031 Ailuropoda melanoleuca
100523066 Sus scrofa
100600667 Nomascus leucogenys
91662 Homo sapiens
378425 Mus musculus
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