anti-Neural Precursor Cell Expressed, Developmentally Down-Regulated 8 (NEDD8) Antibodies

displays differential expression after induction by nerve growth factor [RGD, Feb 2006].. Additionally we are shipping NEDD8 Proteins (31) and NEDD8 Kits (5) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
NEDD8 4738 Q15843
NEDD8 25490 Q71UE8
NEDD8 18002 P29595
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Top anti-NEDD8 Antibodies at antibodies-online.com

Showing 10 out of 132 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated EIA, IHC (p), WB 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated IHC (p), WB Western blot analysis of NEDD8 polyclonal antibody (ABIN388037) in HeLa cell lysate. NEDD8 (arrow) was detected using purified polyclonal antibody. Secondary HRP-anti-rabbit was used for signal visualization with chemiluminescence. Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. BC = breast carcinoma. HC = hepatocarcinoma 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated IHC (p), WB   100 μg Log in to see 4 to 6 Days
$240.00
Details
Human Mouse Un-conjugated EIA, FACS, IF, IHC (p), WB 0.1 mg Log in to see 6 to 8 Days
$423.50
Details
Human Rabbit Un-conjugated IHC (p), WB 0.1 mg Log in to see 6 to 8 Days
$390.50
Details
Human Mouse Un-conjugated ICC, FACS, IHC, ELISA, WB Figure 1: Red: Control Antigen (100 ng), Purple: Antigen (10ng), Green: Antigen (50 ng), Blue: Antigen (100 ng) Figure 2: Flow cytometric analysis of Hela cells using NEDD8 mouse mAb (green) and negative control (red) . 0.1 mg Log in to see 2 to 3 Days
$430.10
Details
Human Rabbit Un-conjugated EIA, IHC (p), WB Human Small Intestine: Formalin-Fixed, Paraffin-Embedded (FFPE) Western blot analysis of extracts from Jurkat cells, using NEDD8 Antibody. The lane on the right is treated with the synthesized peptide. 50 μL Log in to see 11 to 13 Days
$542.85
Details
Human Rabbit Un-conjugated IHC, ELISA, WB Western blot analysis of extracts from Jurkat cells, using NEDD8 Antibody. The lane on the right is treated with the synthesized peptide. Immunohistochemistry analysis of paraffin-embedded human lung carcinoma tissue, using NEDD8 Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Rabbit Un-conjugated ELISA, IHC, WB Western Blot (WB) analysis of specific cells using Neddylin Polyclonal Antibody. 100 μL Log in to see 16 Days
$175.80
Details
Human Rabbit Un-conjugated IHC (p), ELISA, WB Anti-NEDD8 antibody IHC staining of human small intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody  ABIN959353 dilution 1:100. 50 μL Log in to see 7 to 9 Days
$451.00
Details

NEDD8 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-NEDD8 Antibodies

  1. Human Monoclonal NEDD8 Primary Antibody for ICC, FACS - ABIN969546 : Ohki, Funatsu, Konishi, Chiba: The mechanism of poly-NEDD8 chain formation in vitro. in Biochemical and biophysical research communications 2009 (PubMed)

More Antibodies against NEDD8 Interaction Partners

Fruit Fly (Drosophila melanogaster) Neural Precursor Cell Expressed, Developmentally Down-Regulated 8 (NEDD8) interaction partners

  1. the Cul1 (show CUL1 Antibodies)-based SCF (show KITLG Antibodies) complex requires Nedd8 modification for the degradation processes of Ci, Arm, and CycE (show CCNE1 Antibodies) in vivo

  2. Genetic analyses indicate that a balance between neddylation and deneddylation maintained by DEN1 (show SENP8 Antibodies) is crucial for animal viability.

Human Neural Precursor Cell Expressed, Developmentally Down-Regulated 8 (NEDD8) interaction partners

  1. MKK7 (show MAP2K7 Antibodies) undergoes neddylation in human breast cancer cells

  2. complete blocking of CRLs at a higher inhibitor dose-induced cytotoxicity that was amplified by knockdown of CRL (show IL31RA Antibodies) regulator Cand1 (show CAND1 Antibodies).

  3. In conclusion, the authors revealed that E3 ligase HDM2 promotes NEDD8 NEDDylation of HBx to enhance HBx stability and chromatin localization, which in turn favors HBx-dependent transcriptional regulation, cell proliferation, and hepatitis B virus-driven tumor growth.

  4. CUL5 (show CUL5 Antibodies) neddylation may allosterically tune polyubiquitin (show UBB Antibodies) chain length and topology.

  5. This study identifies MyD88 (show MYD88 Antibodies) as a novel substrate of NEDD8, and demonstrate that MyD88 (show MYD88 Antibodies) NEDDylation antagonizes its ubiquitination.

  6. This study provides new knowledge of the CFTR (show CFTR Antibodies) biosynthetic pathway. It suggests that SYVN1 (show SYVN1 Antibodies) and FBXO2 (show FBXO2 Antibodies) represent two distinct multiprotein complexes that may degrade DeltaF508-CFTR (show CFTR Antibodies) in airway epithelia and identifies a new role for NEDD8 in regulating DeltaF508-CFTR (show CFTR Antibodies) ubiquitination.

  7. Neddylation of Smurf1 (show SMURF1 Antibodies) activates its ubiquitin ligase activity and Smurf2 (show SMURF2 Antibodies) exerts Nedd8 ligase activity. This study provided new clues of Smurf2 (show SMURF2 Antibodies) activation regulation.

  8. Nedd8(Q40E) cannot induce the same structural effect on Cul1 (show CUL1 Antibodies)-Rbx1 as wild-type Nedd8.

  9. findings add novel evidence showing, for what we believe the first time, that NEDD8-mediated neddylation is required for normal human endometrial functions

  10. In endothelial dysfunction, HDAC2 (show HDAC2 Antibodies) levels were reciprocally regulated by ectopic expression of NEDD8 and the de-NEDDylating enzyme SENP8 (show SENP8 Antibodies).

Mouse (Murine) Neural Precursor Cell Expressed, Developmentally Down-Regulated 8 (NEDD8) interaction partners

  1. neural precursor cell expressed developmentally downregulated protein 8 (Nedd8) modification of Cul-5 (show CUL5 Antibodies) is required for its interaction with TRAF6 (show TRAF6 Antibodies).

  2. Our findings provide mechanistic evidence of the effects of IAP (show ALPI Antibodies) antagonists in combination with NAE inhibitors, and demonstrate the potential of a new combination therapy for cancer.

  3. a role of Nedd8 in regulating caspase-1 (show CASP1 Antibodies) activation following inflammasome activation

  4. Nedd8 and its associated E2 carrier protein (Ubc12 (show ube2m Antibodies)) and E3-SCF (show KITLG Antibodies) ligase play a key role in regulating the expression and activity of ENaC (show SCNN1A Antibodies) in alveolar pneumocytes.

  5. a new regulatory mechanism of RCAN1 (show RCAN1 Antibodies) function

  6. c-Cbl conjugates neural precursor cell-expressed, developmentally downregulated 8 (NEDD8), a ubiquitin-like protein, to TbetaRII at Lys556 and Lys567.

  7. The NEDD8 pathway appears to play an important role in CD4 (show CD4 Antibodies)+ T-cell-mediated inflammatory responses

  8. Nedd8 and AhR (show AHR Antibodies) localize to overlapping areas in the heart and spinal ganglia, raising the possibility that this interaction may play a role in organogenesis

  9. NEDD8 and ubiquitin function in a redundant manner in controlling receptor endocytic pathways.

  10. SCCRO recruits Ubc12 approximately NEDD8 to the CAND1-Cul1-ROC1 complex but that this is not sufficient to dissociate or overcome the inhibitory effects of CAND1 on cullin neddylation

NEDD8 Antigen Profile

Protein Summary

displays differential expression after induction by nerve growth factor

Gene names and symbols associated with NEDD8

  • CG10679 gene product from transcript CG10679-RA (Nedd8) antibody
  • neural precursor cell expressed, developmentally down-regulated 8 (nedd8) antibody
  • neural precursor cell expressed, developmentally down-regulated 8 (NEDD8) antibody
  • Nedd8 (Nedd8) antibody
  • ubiquitin-like protein Nedd8 (nedd8) antibody
  • NEDD8 protein (nedd8) antibody
  • NEDD8-like (LOC100520086) antibody
  • neural precursor cell expressed, developmentally down-regulated 8 (Nedd8) antibody
  • neural precursor cell expressed, developmentally down-regulated gene 8 (Nedd8) antibody
  • CG10679 antibody
  • DDBDRAFT_0218116 antibody
  • DDBDRAFT_0238041 antibody
  • DDB_0218116 antibody
  • DDB_0238041 antibody
  • Dmel\\CG10679 antibody
  • dNEDD8 antibody
  • GB17785 antibody
  • NEDD-8 antibody
  • nedd8 antibody
  • Rub1 antibody
  • si:zc14a17.5 antibody
  • ubiquitin antibody

Protein level used designations for NEDD8

CG10679-PA , Nedd8-PA , neural precursor cell-expressed developmentally downregulated , neural precursor cell expressed, developmentally down-regulated 8 , Nedd8 , NEDD8 protein , neddylin , ubiquitin-like protein Nedd8 , NEDD8 , neural precursor cell expressed, developmentally down-regulated gene 8 , NEDD-8 , neural precursor cell expressed developmentally down-regulated protein 8

GENE ID SPECIES
35151 Drosophila melanogaster
368667 Danio rerio
480265 Canis lupus familiaris
549727 Xenopus (Silurana) tropicalis
552822 Apis mellifera
704026 Macaca mulatta
715763 Macaca mulatta
8621655 Dictyostelium discoideum AX4
100301786 Oncorhynchus mykiss
100528101 Ictalurus punctatus
100520086 Sus scrofa
4738 Homo sapiens
25490 Rattus norvegicus
286796 Bos taurus
100009008 Oryctolagus cuniculus
18002 Mus musculus
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