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anti-PHD Finger Protein 8 (PHF8) Antibodies

The protein encoded by PHF8 is a histone lysine demethylase that preferentially acts on histones in the monomethyl or dimethyl states. Additionally we are shipping PHF8 Kits (3) and PHF8 Proteins (3) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
PHF8 23133 Q9UPP1
PHF8 317425  
PHF8 320595 Q80TJ7
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Top anti-PHF8 Antibodies at antibodies-online.com

Showing 10 out of 28 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated ELISA, WB 25 μg Log in to see 2 to 3 Days
$220.50
Details
Human Rabbit Un-conjugated WB PHF8 pAb tested by Western blot. Nuclear extract of HeLa cells (20 µg) was probed with PHF8 pAb (1:500 dilution). 100 μL Log in to see 1 to 2 Days
$466.67
Details
Human Rabbit Un-conjugated IHC, IHC (p), WB   0.1 mL Log in to see 5 to 7 Days
$477.75
Details
Human Rabbit Un-conjugated IP, WB   100 μL Log in to see 8 to 10 Days
$815.83
Details
Human Rabbit Un-conjugated IP, WB   100 μL Log in to see 8 to 10 Days
$815.83
Details
Human Rabbit FITC IF (p)   100 μL Log in to see 14 to 21 Days
$357.50
Details
Human Rabbit Alexa Fluor 555 IF (p)   100 μL Log in to see 14 to 21 Days
$357.50
Details
Human Rabbit Alexa Fluor 647 IF (p)   100 μL Log in to see 14 to 21 Days
$357.50
Details
Human Rabbit Alexa Fluor 488 IF (p)   100 μL Log in to see 14 to 21 Days
$357.50
Details
Human Rabbit Alexa Fluor 350 IF (p)   100 μL Log in to see 14 to 21 Days
$357.50
Details

PHF8 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Human , , , ,
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Rat (Rattus) ,


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Mouse (Murine) , ,


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More Antibodies against PHF8 Interaction Partners

Human PHD Finger Protein 8 (PHF8) interaction partners

  1. PHF8 reduces the H3K9me2 level at the E2F4 (show E2F4 Antibodies) transcriptional start site, demonstrating a direct function of PHF8 in endothelial E2F4 (show E2F4 Antibodies) gene regulation

  2. PHF2 (show PHF1 Antibodies) is likely to repress rDNA transcription by competing with PHF8 for binding of ribosomal DNA promoter and by recruiting H3K9me2/3 methyltransferase SUV39H1 (show SUV39H1 Antibodies).

  3. PHF8 promotes lung cancer cell growth and survival by regulating miR (show MLXIP Antibodies)-21.

  4. knockdown of PHF8 led to a reduction in the number of migratory and invasive cells. Furthermore, downregulation of PHF8 attenuated the tumorigenicity of ESCC cells in vivo.

  5. PHF8 is regulated by APC (show APC Antibodies)(cdc20 (show CDC20 Antibodies)) and plays an important role in the G2/M transition.

  6. study identified the histone demethylase (show MBD2 Antibodies) PHF8 as a coactivator that is specifically recruited by RAR-alpha (show RARA Antibodies) fusions to activate expression of their downstream targets upon all-trans retinoic acid treatment in acute promyelocytic leukemia (show PML Antibodies)

  7. Results show that PHF8 controls the expression of genes involved in cell adhesion and cytoskeleton organization such as RhoA (show RHOA Antibodies), Rac1 and GSK3beta (show GSK3b Antibodies).

  8. a role of PHF8 in cell migration and invasion

  9. PHF8 is a histone demethylase and coactivator for RARalpha (show CDKN2D Antibodies)and that the F279S mutation identified in an XLMR patient results in loss of its demethylase activity.

  10. H3K9me2 level was elevated in the promoter region of the rDNA gene in PHF8 knockdown cells and reduced significantly when the wild type but not the catalytically inactive H247A mutant PHF8 was overexpressed.

Mouse (Murine) PHD Finger Protein 8 (PHF8) interaction partners

  1. PHF8 overexpression reversed cardiac dysfunction, hypertrophy and fibrosis upon pressure overload in PHF8 transgenic mice.

  2. The gene knockdown of PHF8 in mouse embryonic carcinoma P19 (show CDKN2D Antibodies) cells impairs RA-induced neuronal differentiation.

  3. an important function of PHF8 is in midline formation and in the development of cognitive abilities, and may have a role in X linked mental retardation associated with cleft lip/palate

Zebrafish PHD Finger Protein 8 (PHF8) interaction partners

  1. PHF8 regulates zebrafish neuronal cell survival and jaw development in part by directly regulating the expression of the homeodomain transcription factor MSX1/MSXB, which functions downstream of multiple signalling and developmental pathways

PHF8 Antigen Profile

Protein Summary

The protein encoded by this gene is a histone lysine demethylase that preferentially acts on histones in the monomethyl or dimethyl states. The encoded protein requires Fe(2+) ion, 2-oxoglutarate, and oxygen for its catalytic activity. Defects in this gene are a cause of mental retardation syndromic X-linked Siderius type (MRXSSD). Four transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with PHF8

  • PHD finger protein 8 (PHF8) antibody
  • PHD finger protein 8 (Phf8) antibody
  • PHD finger protein 8 (phf8) antibody
  • RIKEN cDNA 4921501E09 gene (4921501E09Rik) antibody
  • 9830141C09Rik antibody
  • JHDM1F antibody
  • mKIAA1111 antibody
  • MRXSSD antibody
  • PHF8 antibody
  • RGD1561065 antibody
  • ZNF422 antibody
  • zPHF8 antibody

Protein level used designations for PHF8

histone lysine demethylase PHF8 , jumonji C domain-containing histone demethylase 1F , KIAA1111-like protein , PHD finger protein 8-like

GENE ID SPECIES
23133 Homo sapiens
491897 Canis lupus familiaris
100520413 Sus scrofa
513959 Bos taurus
317425 Rattus norvegicus
320595 Mus musculus
566534 Danio rerio
74042 Mus musculus
Selected quality suppliers for anti-PHF8 (PHF8) Antibodies
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