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Poliovirus Receptor-Related 3 Proteins (PVRL3)

PVRL3 encodes a member of the nectin family of proteins, which function as adhesion molecules at adherens junctions. Additionally we are shipping PVRL3 Antibodies (98) and PVRL3 Kits (1) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
PVRL3 25945 Q9NQS3
PVRL3 58998 Q9JLB9
Rat PVRL3 PVRL3 288124  
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Top PVRL3 Proteins at antibodies-online.com

Showing 10 out of 17 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Human Cells Human His tag 100 μg Log in to see 16 Days
$382.80
Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 49 to 54 Days
$4,244.78
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 49 to 54 Days
$6,041.49
Details
HOST_Escherichia coli (E. coli) Human His tag,T7 tag 100 μg Log in to see 11 to 13 Days
$739.20
Details
HOST_Escherichia coli (E. coli) Mouse His tag,T7 tag 100 μg Log in to see 11 to 13 Days
$774.40
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
HOST_HEK293 Human His tag   50 μg Log in to see 5 Days
$280.50
Details
HOST_HEK293 Human Un-conjugated   100 μg Log in to see 4 to 6 Days
$635.88
Details

PVRL3 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , , , , ,
, , ,
Mouse (Murine) ,
, ,

Top referenced PVRL3 Proteins

  1. Human PVRL3 Protein expressed in Human Cells - ABIN2003491 : Reymond, Borg, Lecocq, Adelaide, Campadelli-Fiume, Dubreuil, Lopez: Human nectin3/PRR3: a novel member of the PVR/PRR/nectin family that interacts with afadin. in Gene 2000 (PubMed)
    Show all 4 references for ABIN2003491

More Proteins for Poliovirus Receptor-Related 3 (PVRL3) Interaction Partners

Human Poliovirus Receptor-Related 3 (PVRL3) interaction partners

  1. Data suggest that 3 independent regions of TcdB (Clostridium difficile toxin B; 1372-1493, 1493-1848, 1851-2366) contribute to binding and entry of TcdB into mammalian cells; residues 1372-1493 are sufficient for interaction with PVRL3.

  2. Expression of nectin-3 in pancreatic cancer can be a prognostic factor.

  3. PVRL3 is a physiologically relevant binding partner that can serve as a target for the prevention of TcdB-induced cytotoxicity in C. difficile infection.

  4. Nectin-3 is associated with the formation of cell junctions and be a putative suppressor molecule to the invasion of breast cancer cells.

  5. Nectin-3 trans-interacts with Nectin-2 (show PVRL2 Proteins) to promote lymphocyte and monocyte extravasation.

  6. Data suggest that expression of nectin-3 is up-regulated in eutopic endometrium of patients with endometriosis as compared with control subjects and up-regulated in all endometriotic lesions investigated compared with eutopic endometrium.

Mouse (Murine) Poliovirus Receptor-Related 3 (PVRL3) interaction partners

  1. -afadin-specific C-terminal inserts may be involved in its preference of binding to nectin-3 and raise the possibility that there are proteins other than nectins that more preferentially bind s-afadin than l-afadin.

  2. owing to the loss of Nectin-3, hair cells contact each other inappropriately and form abnormal junctions, ultimately resulting in abnormal hair bundle orientation and morphology

  3. Results indicate that PLEKHA7 plays a cooperative role with nectin and afadin in the proper formation of Adherens junction (AJ) in epithelial cell.

  4. This study demonstrated that nectin1- and nectin3-mediated interactions between Cajal-Retzius cells cells and migrating neurons are critical for radial migration.

  5. Cell adhesion molecule (show MCAM Proteins) nectin-3 is required for the effects of corticotropin releasing hormone (show CRH Proteins) receptor (show NR4A1 Proteins) (CRHR)1 (show CRHR1 Proteins) on cognition and structural remodeling after early-life stress exposure.

  6. Nectin-3, which forms hetero-trans-dimers with nectin-1 (show PVRL1 Proteins), undergoes intramembrane cleavage mediated by PS1 (show PSEN1 Proteins)/gamma-secretase.

  7. hair cells and supporting cells express nectin-1 (show PVRL1 Proteins) and -3, respectively; their interaction mediates the heterotypic adhesion between these 2 cell types; nectin-1 (show PVRL1 Proteins) and -3 promote the formation of the checkerboard-like pattern of the auditory epithelia

  8. Results suggest that heterophilic interaction between nectin-1 (show PVRL1 Proteins) and nectin-3 recruits desmosomal junctions, and that these are required for proper enamel formation.

  9. nectin-afadin system plays essential roles in coupling cell-cell adhesion and the cortical actin scaffold in spermatids at Sertoli-spermatid junctions and in subsequent sperm morphogenesis

  10. Overexpressed nectin recruited N-cadherin DN to the nectin-based cell-cell adhesion sites in an afadin-dependent manner.

PVRL3 Protein Profile

Protein Summary

This gene encodes a member of the nectin family of proteins, which function as adhesion molecules at adherens junctions. This family member interacts with other nectin-like proteins and with afadin, a filamentous actin-binding protein involved in the regulation of directional motility, cell proliferation and survival. This gene plays a role in ocular development involving the ciliary body. Mutations in this gene are believed to result in congenital ocular defects. Alternative splicing results in multiple transcript variants.

Gene names and symbols associated with PVRL3

  • poliovirus receptor-related 3 (Pvrl3)
  • poliovirus receptor-related 3 (PVRL3)
  • poliovirus receptor-related protein 3-like (LOC100518152)
  • poliovirus receptor-related 3 (LOC100350924)
  • poliovirus receptor-related 3 (pvrl3)
  • 2610301B19Rik protein
  • 3000002N23Rik protein
  • 4921513D19Rik protein
  • AA407785 protein
  • AU016832 protein
  • AW538082 protein
  • CD113 protein
  • CDW113 protein
  • NECTIN-3 protein
  • PPR3 protein
  • PRR3 protein
  • PVRL3 protein
  • PVRR3 protein

Protein level used designations for PVRL3

poliovirus receptor-related 3 , poliovirus receptor-related protein 3-like , nectin 3 , poliovirus receptor-related protein 3 , nectin-3

GENE ID SPECIES
100732753 Cavia porcellus
478559 Canis lupus familiaris
100518152 Sus scrofa
460576 Pan troglodytes
100350924 Oryctolagus cuniculus
100414225 Callithrix jacchus
100439172 Pongo abelii
100549194 Meleagris gallopavo
100560246 Anolis carolinensis
100579224 Nomascus leucogenys
25945 Homo sapiens
58998 Mus musculus
288124 Rattus norvegicus
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