You are viewing an incomplete version of our website. Please click to reload the website as full version.

anti-Sirtuin 2 (SIRT2) Antibodies

SIRT2 encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Additionally we are shipping Sirtuin 2 Proteins (23) and Sirtuin 2 Kits (16) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
SIRT2 22933 Q8IXJ6
SIRT2 64383 Q8VDQ8
SIRT2 361532 Q5RJQ4
How to order from antibodies-online
  • +1 877 302 8632
  • +1 888 205 9894 (toll-free)
  • Order online
  • orders@antibodies-online.com

Top anti-Sirtuin 2 Antibodies at antibodies-online.com

Showing 10 out of 126 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Cow Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$229.00
Details
Cow Rabbit Un-conjugated WB 0.1 mg Log in to see 6 to 8 Days
$456.50
Details
Human Rabbit Un-conjugated EIA, IHC (p), WB Immunohistochemical staining of human brain tissue using AP30786PU-N a... Western blot analysis of SIRT2 in human brain lysate with this product... 0.1 mg Log in to see 6 to 8 Days
$401.50
Details
Human Rabbit Un-conjugated EIA, IHC (p), WB Immunohistochemical staining of human brain tissue using AP30785PU-N S... Western blot analysis of SIRT2 in Mouse brain lysate with AP30785PU-N ... 0.1 mg Log in to see 6 to 8 Days
$401.50
Details
Human Rabbit Un-conjugated ELISA, WB   100 μg Log in to see 2 to 3 Days
$275.00
Details
Human Rat Un-conjugated WB   100 μg Log in to see 1 to 2 Days
$466.67
Details
Human Rabbit Un-conjugated IHC (p), WB Anti-SIRT2 Picoband antibody,  IHC(P): Rat Brain Tissue Anti-SIRT2 Picoband antibody,  IHC(P): Mouse Brain Tissue 100 μg Log in to see 4 to 6 Days
$240.00
Details
Human Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
$551.83
Details

SIRT2 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality
Human , , , ,
, ,
Mouse (Murine) , , , ,

Rat (Rattus) , , , ,

Top referenced anti-Sirtuin 2 Antibodies

  1. Human Polyclonal SIRT2 Primary Antibody for EIA, IHC (p) - ABIN500724 : Yamamoto, Schoonjans, Auwerx: Sirtuin functions in health and disease. in Molecular endocrinology (Baltimore, Md.) 2007 (PubMed)
    Show all 5 references for ABIN500724

  2. Human Polyclonal SIRT2 Primary Antibody for EIA, IHC (p) - ABIN500726 : North, Marshall, Borra, Denu, Verdin: The human Sir2 ortholog, SIRT2, is an NAD+-dependent tubulin deacetylase. in Molecular cell 2003 (PubMed)
    Show all 4 references for ABIN500726

  3. Cow (Bovine) Polyclonal SIRT2 Primary Antibody for WB - ABIN493462 : Jing, Gesta, Kahn: SIRT2 regulates adipocyte differentiation through FoxO1 acetylation/deacetylation. in Cell metabolism 2007 (PubMed)
    Show all 3 references for ABIN493462

  4. Cow (Bovine) Polyclonal SIRT2 Primary Antibody for WB - ABIN2779604 : Borra, Langer, Slama, Denu: Substrate specificity and kinetic mechanism of the Sir2 family of NAD+-dependent histone/protein deacetylases. in Biochemistry 2004 (PubMed)
    Show all 2 references for ABIN2779604

  5. Human Monoclonal SIRT2 Primary Antibody for WB - ABIN2668611 : Pandithage, Lilischkis, Harting, Wolf, Jedamzik, Lüscher-Firzlaff, Vervoorts, Lasonder, Kremmer, Knöll, Lüscher: The regulation of SIRT2 function by cyclin-dependent kinases affects cell motility. in The Journal of cell biology 2008 (PubMed)

  6. Human Polyclonal SIRT2 Primary Antibody for ELISA, WB - ABIN1452045 : Afshar, Murnane: Characterization of a human gene with sequence homology to Saccharomyces cerevisiae SIR2. in Gene 1999 (PubMed)

  7. Human Polyclonal SIRT2 Primary Antibody for WB - ABIN2779605 : Lennerz, Fatho, Gentilini, Frye, Lifke, Ferel, Wölfel, Huber, Wölfel: The response of autologous T cells to a human melanoma is dominated by mutated neoantigens. in Proceedings of the National Academy of Sciences of the United States of America 2005 (PubMed)

More Antibodies against Sirtuin 2 Interaction Partners

Fruit Fly (Drosophila melanogaster) Sirtuin 2 (SIRT2) interaction partners

  1. Sirt2 has an role in the regulation of mitochondrial energy metabolism.

Arabidopsis thaliana Sirtuin 2 (SIRT2) interaction partners

  1. SRT2 is important in fine-tuning mitochondrial energy metabolism.

  2. AtSRT2 is a deacetylase that negatively regulates the plant basal defense and PR1 (show TMEM37 Antibodies) expression.

Human Sirtuin 2 (SIRT2) interaction partners

  1. Emerging Role of Sirtuin 2 in the Regulation of Mammalian Metabolism

  2. Under hypoxic conditions, SIRT2 inhibition increased the ubiquitination of HIF-1alpha (show HIF1A Antibodies) in a VHL (show VHL Antibodies)-dependent manner, leading to the degradation of HIF-1alpha (show HIF1A Antibodies) via a proteasomal pathway.

  3. Regulation of protein acetylation by SIRT2 plays a central role in platelet function. The effects of SIRT2 are mediated in part by the acetylation and inhibition of Akt (show AKT1 Antibodies).

  4. high-resolution structures of human Sirt2 in complex with highly selective drug-like inhibitors that show a unique inhibitory mechanism, are presented.

  5. Expression of sirtuin 1 (show SIRT1 Antibodies) and 2 is associated with poor prognosis in non-small cell lung cancer patients

  6. In conclusion our data reveal that resveratrol induced premature senescence is associated with SIRT1 (show SIRT1 Antibodies) and SIRT2 down regulation in human dermal fibroblasts

  7. The study reports the formation of a multiprotein complex at the G2-to-M transition in vitro and in vivo. Group IVA cytosolic phospholipase A2 (cPLA2-alpha (show PLA2G4A Antibodies)) acts as a bridge in this complex to promote binding of SIRT2 to cyclin A (show CCNA2 Antibodies)-Cdk2 (show CDK2 Antibodies).

  8. The crystal structure of SIRT2 in complex with a thiomyristoyl peptide reveals that SIRT2 possesses a large hydrophobic pocket that can accommodate the myristoyl group.

  9. SIRT1 (show SIRT1 Antibodies) inhibition caused cell death, while SIRT2 inhibition resulted in cell cycle arrest. In conclusion, we report the overexpression of SIRT2 and SIRT7 (show SIRT7 Antibodies) proteins in cervical cancer

  10. SIRT2 and SIRT6 (show SIRT6 Antibodies) are expressed in retinoblastoma, as well as in some normal ocular structures.

Cow (Bovine) Sirtuin 2 (SIRT2) interaction partners

  1. The results indicate that the variations in the class I sirtuin (show SIRT1 Antibodies) genes and their corresponding genotypes may be considered as molecular markers for economic traits in cattle breeding.

  2. An association analysis showed that the two loci of SIRT2 were significantly correlated with some body size traits and the H2H2 (-CT-CT (show CALCA Antibodies)-) diplotypes performed better than other combinations.

  3. Data suggest that the silent information regulator 2 (SIRT2) gene may be a candidate gene for marker-assisted selection in the development of breeding programs for Qinchuan cattle.

Mouse (Murine) Sirtuin 2 (SIRT2) interaction partners

  1. Results suggest a role for Hdac5 (show HDAC5 Antibodies) and Sirt2 in neuronal adaptations induced by chronic stress and antidepressant treatment and highlight the therapeutic potential of these targets in the treatment of depression

  2. Sirt2 deletion results in radiation-induced alteration of the mouse brain proteome.

  3. Sirt2 expression has a transitory effect in M. tuberculosis infection

  4. we postulate that Sirt2 mediates myelin-dependent neuronal dysfunction during the early phase after ischemic stroke

  5. The study reports the formation of a multiprotein complex at the G2-to-M transition in vitro and in vivo. Group IVA cytosolic phospholipase A2 (cPLA2-alpha (show PLA2G4A Antibodies)) acts as a bridge in this complex to promote binding of SIRT2 to cyclin A (show CCNA2 Antibodies)-Cdk2 (show CDK2 Antibodies).

  6. Lipopolysaccharide-induced increases in microglia NOS (show NOS Antibodies) and cytokine mRNA were attenuated in the cells with SIRT2 silencing-produced decreases in the SIRT2 level. This suggests that SIRT2 is required for lipopolysaccharide-induced microglial activation

  7. Disruption of the SIRT2-beta-catenin (show CTNNB1 Antibodies) interaction represents an endogenous therapeutic target to prevent transformation and preserve the integrity of aging cells against exogenous stressors such as reactive oxygen species.

  8. Tissue-specific deregulation of selected HDACs characterizes ALS progression in mouse models: pharmacological characterization of SIRT1 (show SIRT1 Antibodies) and SIRT2 pathways.

  9. long-term vitamin E-deficiency significantly decreased the expression of silent mating type information regulation (SIRT)-2 mRNA compared to short-term deficiency.

  10. data indicated that Sirt2 could enhance myoblast proliferation, shorten the G1 phase in murine C2C12 myoblasts by inducing cell cycle regulatory proteins cyclin D1 (show CCND1 Antibodies) and cdk2 (show CDK2 Antibodies) kinase, and suppressing p21 (show D4S234E Antibodies)

Sirtuin 2 (SIRT2) Antigen Profile

Protein Summary

This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined\; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class I of the sirtuin family. Several transcript variants are resulted from alternative splicing of this gene.

Gene names and symbols associated with anti-Sirtuin 2 (SIRT2) Antibodies

  • CG5085 gene product from transcript CG5085-RA (Sirt2) antibody
  • sirtuin (silent mating type information regulation 2 homolog) 2 (S. cerevisiae) (SIRT2) antibody
  • sirtuin 2 (sir2) antibody
  • sirtuin 2 (SIRT2) antibody
  • NAD-dependent deacetylase sirtuin 2 homolog (Sirt2) antibody
  • sirtuin 2 (SRT2) antibody
  • sirtuin 2 (silent mating type information regulation 2, homolog) 2 (S. cerevisiae) (sirt2) antibody
  • sirtuin 2 (Sirt2) antibody
  • 5730427M03Rik antibody
  • AtSRT2 antibody
  • BmSirt2 antibody
  • CG5085 antibody
  • D.mel2 antibody
  • Dmel\\CG5085 antibody
  • dSIRT2 antibody
  • SIR2 antibody
  • Sir2l antibody
  • SIR2L2 antibody
  • Sirt2 antibody
  • sirtuin 2 antibody
  • T2K12.8 antibody
  • wu:fb57d05 antibody
  • zgc:55966 antibody
  • zgc:77003 antibody

Protein level used designations for anti-Sirtuin 2 (SIRT2) Antibodies

CG5085-PA , Sirt2-PA , sirtuin (silent mating type information regulation 2 homolog) 2 (S. cerevisiae) , sirtuin 2 , NAD-dependent deacetylase SIRT2 , NAD-dependent deacetylase sirtuin-2 , histone NADC , silent information regulator 2 , nicotinamide adenine dinucleotide-dependent histone deacetylase , NAD-dependent deacetylase sirtuin 2 homolog , NAD-dependent protein deacetylase sirtuin-2 , SIR2-like protein 2 , regulatory protein SIR2 homolog 2 , sir2-related protein type 2 , sirtuin type 2 , sirtuin-like protein 2 , mSIR2L2 , silent mating type information regulation 2, (S.cerevisiae, homolog)-like; sirtuin 2 , 5E5 antigen

GENE ID SPECIES
42414 Drosophila melanogaster
456013 Pan troglodytes
495688 Xenopus laevis
548628 Gallus gallus
612558 Canis lupus familiaris
692483 Bombyx mori
830782 Arabidopsis thaliana
100380582 Salmo salar
22933 Homo sapiens
100125964 Sus scrofa
504463 Bos taurus
64383 Mus musculus
361532 Rattus norvegicus
100172430 Pongo abelii
322309 Danio rerio
Selected quality suppliers for anti-Sirtuin 2 (SIRT2) Antibodies
Did you look for something else?