anti-Succinate Dehydrogenase Complex, Subunit B, Iron Sulfur (Ip) (SDHB) Antibodies

Complex II of the respiratory chain, which is specifically involved in the oxidation of succinate, carries electrons from FADH to CoQ. Additionally we are shipping Succinate Dehydrogenase Complex, Subunit B, Iron Sulfur (Ip) Proteins (12) and Succinate Dehydrogenase Complex, Subunit B, Iron Sulfur (Ip) Kits (5) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
SDHB 6390 P21912
SDHB 67680 Q9CQA3
SDHB 298596 P21913
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Top anti-Succinate Dehydrogenase Complex, Subunit B, Iron Sulfur (Ip) Antibodies at antibodies-online.com

Showing 10 out of 128 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated WB <b>WB Suggested Anti-SDHB Antibody Titration: </b>0.2-1 ug/ml<br><b>ELISA Titer: </b>1:62500<br><b>Positive Control: </b>Jurkat cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-Sdhb AntibodyTitration: 1.0 µg/mL <br /> Positive Control: Mouse Heart 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated IHC (p), WB Anti-SDHB antibody, Western blotting All lanes: Anti SDHB  at 0.5ug/ml Lane 1: Rat Testis Tissue Lysate at 50ug Lane 2: Rat Cardiac Muscle Tissue Lysate at 50ug Lane 3: Jurkat Whole Cell Lysate at 40ug Predicted bind size: 32KD Observed bind size: 32KD Anti-SDHB antibody, IHC(P) IHC(P): Rat Cardiac Muscle Tissue 100 μg Log in to see 4 to 6 Days
$200.00
Details
Human Rabbit Un-conjugated ICC, IF, IHC, IHC (p), WB Immunocytochemistry/Immunofluorescence: SDHB Antibody [NBP1-54154] - ICC staining of SDHB in HeLa cells with FITC (green). Nuclei were counterstained with Dapi (blue). Western Blot: SDHB Antibody [NBP1-54154] - Detection of SDHB in mouse kidney lysate. 0.1 mL Log in to see 7 to 9 Days
$381.94
Details
Human Rabbit Un-conjugated ICC, IF, IHC, IHC (p), SimWes, WB Simple Western: SDHB Antibody [NBP1-87069] - Simple Western lane view shows a specific band for SDHB in 0.2 mg/ml of RT-4 (left) and U-251MG sp (right) lysate. This experiment was performed under reducing conditions using the 12-230 kDa separation system. Simple Western: SDHB Antibody [NBP1-87069] - Electropherogram image(s) of corresponding Simple Western lane view. SDHB antibody was used at 1:20 dilution on RT-4 and U-251MG sp lysates(s). 0.1 mL Log in to see 10 to 13 Days
$439.69
Details
Human Goat Un-conjugated ELISA, WB ABIN185447 (0.03µg/ml) staining of Human Liver lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 100 μg Log in to see 6 to 7 Days
$326.89
Details
Human Rabbit Un-conjugated ICC, IF, IHC (p), WB WB Image SDHB antibody [C2C3], C-term detects SDHB protein by Western blot analysis. A. 30 µg Neuro2A whole cell lysate/extract 12 % SDS-PAGE SDHB antibody [C2C3], C-term , dilution: 1:1000 IHC-P Image SDHB antibody [C2C3], C-term detects SDHB protein at mitochindria on human colon carcinoma by immunohistochemical analysis. Sample: Paraffin-embedded human colon carcinoma. SDHB antibody [C2C3], C-term , diluted at 1:500. 100 μL Log in to see 1 to 2 Days
$358.60
Details
Human Rabbit Un-conjugated ELISA, IHC (p), WB Immunohistochemistry (IHC) analysis of paraffin-embedded Human Muscle, antibody was diluted at 1:100. 100 μL Log in to see 16 Days
$175.80
Details
Human Rabbit Un-conjugated WB SDHB Antibody (C-term) (ABIN1881781) western blot analysis in 293 cell line lysates (35 µg/lane). This demonstrates the SDHB antibody detected the SDHB protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Cow Rabbit Un-conjugated WB 50 μg Log in to see 7 to 9 Days
$551.83
Details

SDHB Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-Succinate Dehydrogenase Complex, Subunit B, Iron Sulfur (Ip) Antibodies

  1. Human Polyclonal SDHB Primary Antibody for ICC, IF - ABIN4352356 : van Nederveen, Gaal, Favier, Korpershoek, Oldenburg, de Bruyn, Sleddens, Derkx, Rivière, Dannenberg, Petri, Komminoth, Pacak, Hop, Pollard, Mannelli, Bayley, Perren, Niemann, Verhofstad, de Bruïne et al.: An immunohistochemical procedure to detect patients with paraganglioma and phaeochromocytoma with germline SDHB, SDHC, or SDHD gene mutations: a retrospective and prospective analysis. ... in The Lancet. Oncology 2009 (PubMed)
    Show all 15 Pubmed References

  2. Human Polyclonal SDHB Primary Antibody for WB - ABIN1881781 : Cerecer-Gil, Figuera, Llamas, Lara, Escamilla, Ramos, Estrada, Hussain, Gaal, Korpershoek, de Krijger, Dinjens, Devilee, Bayley: Mutation of SDHB is a cause of hypoxia-related high-altitude paraganglioma. in Clinical cancer research : an official journal of the American Association for Cancer Research 2010 (PubMed)
    Show all 4 Pubmed References

  3. Human Polyclonal SDHB Primary Antibody for ICC, IF - ABIN4352351 : Morton, Beltram, Carter, Michailidou, Gorjanc, McFadden, Barrios-Llerena, Rodriguez-Cuenca, Gibbins, Aird, Moreno-Navarrete, Munger, Svenson, Gastaldello, Ramage, Naredo, Zeyda, Wang, Howie, Saari et al.: Genetic identification of thiosulfate sulfurtransferase as an adipocyte-expressed antidiabetic target in mice selected for leanness. ... in Nature medicine 2016 (PubMed)
    Show all 2 Pubmed References

  4. Human Polyclonal SDHB Primary Antibody for ELISA, WB - ABIN269796 : Selak, Armour, MacKenzie, Boulahbel, Watson, Mansfield, Pan, Simon, Thompson, Gottlieb: Succinate links TCA cycle dysfunction to oncogenesis by inhibiting HIF-alpha prolyl hydroxylase. in Cancer cell 2005 (PubMed)

  5. Cow (Bovine) Polyclonal SDHB Primary Antibody for WB - ABIN2783181 : Cascón, Landa, López-Jiménez, Díez-Hernández, Buchta, Montero-Conde, Leskelä, Leandro-García, Letón, Rodríguez-Antona, Eng, Neumann, Robledo: Molecular characterisation of a common SDHB deletion in paraganglioma patients. in Journal of medical genetics 2008 (PubMed)
    Show all 2 Pubmed References

More Antibodies against Succinate Dehydrogenase Complex, Subunit B, Iron Sulfur (Ip) Interaction Partners

Fruit Fly (Drosophila melanogaster) Succinate Dehydrogenase Complex, Subunit B, Iron Sulfur (Ip) (SDHB) interaction partners

  1. sdhB mutant is hypersensitive to oxygen and displays hallmarks of a progeroid syndrome

Human Succinate Dehydrogenase Complex, Subunit B, Iron Sulfur (Ip) (SDHB) interaction partners

  1. SDHB mutation is associated with metastatic pheochromocytoma.

  2. we found a higher estimated penetrance compared to several other studies, and a striking difference in age-related penetrance between male and female SDHB mutation carriers with no association between mutation and gender or tumor location

  3. LASS5 (show LASS5 Antibodies) interacts with SDHB and synergistically represses p53 (show TP53 Antibodies) and p21 (show CDKN1A Antibodies) activity.

  4. A novel SDHB germline mutation in a paraganglioma

  5. SDHB-related tumours are picked up as early as 2 years after initial negative surveillance scan

  6. miR (show MLXIP Antibodies)-183 cluster (miR (show MLXIP Antibodies)-96/182/183) are related to clinical parameters and SDHB expression in pheochromocytomas.

  7. In SDHB mutation carriers, a lower rate of metastatic disease and a higher number of head and neck paragangliomas compared to previous reports was observed in a nationwide study in the Netherlands.

  8. Loss of FH immunohistochemical (IHC) expression in cutaneous leiomyomas is a sensitive and specific marker for detection of hereditary leiomyomatosis and renal cell carcinoma (show MOK Antibodies) (HLRCC (show FH Antibodies)). FH expression by IHC was absent in 9 specimens and retained in 85 specimens and 2 cases were equivocal with minimal FH expression while succinate dehydrogenase B expression was retained in 95 specimens and equivocal in 1 specimen.

  9. Identify small molecule binding to the succinate dehydrogenase subunit B (SDHB) protein of complex II of the mitochondrial electron transfer chain to block mitochondrial apoptotic pathway.

  10. We have shown that ASO treatment diminished aberrant splicing and increased ISCU (show ISCU Antibodies) protein levels in both patient fibroblasts and patient myotubes in a concentration dependent fashion. Upon ASO treatment, levels of SDHB in patient myotubular cell lines increased to levels observed in control myotubular cell lines

Pig (Porcine) Succinate Dehydrogenase Complex, Subunit B, Iron Sulfur (Ip) (SDHB) interaction partners

  1. tissue expression analysis indicated that that swine SDHB, SNRPA (show SNRPA Antibodies) and CRYBB1 (show CRYBB1 Antibodies) gene were differentially expressed in tissues including fat, lung, muscle, small intestine, kidney, large intestine, spleen and liver

Mouse (Murine) Succinate Dehydrogenase Complex, Subunit B, Iron Sulfur (Ip) (SDHB) interaction partners

  1. Data show that lack of succinate dehydrogenase (SDH (show SDHA Antibodies)) activity commits cells to consume extracellular pyruvate.

  2. Using Sdhb(+/-) mice, we provide evidence that pituitary hyperplasia in SDHx-deficient cells may be the initial abnormality in the cascade of events leading to pituitary adenoma formation.

  3. Tumor-derived FH and SDH (show SDS Antibodies) mutations accumulate fumarate and succinate, leading to enzymatic inhibition of multiple alpha-KG-dependent dioxygenases and consequent alterations of genome-wide histone and DNA methylation (show HELLS Antibodies).

  4. Data show that two subunits of complex II (succinate dehydrogenase (show SDHD Antibodies), or SDH (show SDS Antibodies)), SDHA (show SDHA Antibodies) and SDHB, interacted specifically with SIRT3 (show SIRT3 Antibodies).

Succinate Dehydrogenase Complex, Subunit B, Iron Sulfur (Ip) (SDHB) Antigen Profile

Protein Summary

Complex II of the respiratory chain, which is specifically involved in the oxidation of succinate, carries electrons from FADH to CoQ. The complex is composed of four nuclear-encoded subunits and is localized in the mitochondrial inner membrane. The iron-sulfur subunit is highly conserved and contains three cysteine-rich clusters which may comprise the iron-sulfur centers of the enzyme. Sporadic and familial mutations in this gene result in paragangliomas and pheochromocytoma, and support a link between mitochondrial dysfunction and tumorigenesis.

Gene names and symbols associated with SDHB

  • succinate dehydrogenase complex, subunit B, iron sulfur (Ip) (SDHB) antibody
  • succinate dehydrogenase [ubiquinone] iron-sulfur subunit 3 (SDH2-3) antibody
  • Succinate dehydrogenase B (SdhB) antibody
  • succinate dehydrogenase complex, subunit B, iron sulfur (Ip) (sdhb) antibody
  • succinate dehydrogenase complex, subunit B, iron sulfur (Ip) (Sdhb) antibody
  • 0710008N11Rik antibody
  • CG3283 antibody
  • CWS2 antibody
  • Dmel\\CG3283 antibody
  • fj46d06 antibody
  • IP antibody
  • PGL4 antibody
  • SDH antibody
  • SDH-Ip antibody
  • SDH1 antibody
  • SDH2 antibody
  • sdhB antibody
  • SDHIP antibody
  • succinate dehydrogenase 2-3 antibody
  • wu:fj46d06 antibody

Protein level used designations for SDHB

succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial , succinate dehydrogenase complex subunit B , CG3283-PA , COMPLEX II: iron-sulfur subunit , SdhB-PA , iron-sulfur protein subunit of succinate dehydrogenase , succinate dehydrogenase , succinate dehydrogenase B , succinate dehydrogenase Iron-sulfur , succinate dehydrogenase Iron-sulfur protein , succinate dehydrogenase iron protein , succinate dehydrogenase subunit b , iron-sulfur subunit of complex II , Iron-sulfur subunit of complex II , IP , ip

GENE ID SPECIES
100050091 Equus caballus
770063 Arabidopsis thaliana
35590 Drosophila melanogaster
100144957 Xenopus (Silurana) tropicalis
6390 Homo sapiens
478217 Canis lupus familiaris
414412 Sus scrofa
286840 Bos taurus
100328585 Oryctolagus cuniculus
67680 Mus musculus
298596 Rattus norvegicus
562149 Danio rerio
379939 Xenopus laevis
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