Use your antibodies-online credentials, if available.
No Products on your Comparison List.
Your basket is empty.
Find out more
Complex II of the respiratory chain, which is specifically involved in the oxidation of succinate, carries electrons from FADH to CoQ. Additionally we are shipping Succinate Dehydrogenase Complex, Subunit B, Iron Sulfur (Ip) Proteins (12) and Succinate Dehydrogenase Complex, Subunit B, Iron Sulfur (Ip) Kits (5) and many more products for this protein.
Showing 10 out of 123 products:
Human Polyclonal SDHB Primary Antibody for ICC, IF - ABIN4352356
van Nederveen, Gaal, Favier, Korpershoek, Oldenburg, de Bruyn, Sleddens, Derkx, Rivière, Dannenberg, Petri, Komminoth, Pacak, Hop, Pollard, Mannelli, Bayley, Perren, Niemann, Verhofstad, de Bruïne et al.: An immunohistochemical procedure to detect patients with paraganglioma and phaeochromocytoma with germline SDHB, SDHC, or SDHD gene mutations: a retrospective and prospective analysis. ... in The Lancet. Oncology 2009
Show all 15 references for ABIN4352356
Human Polyclonal SDHB Primary Antibody for WB - ABIN1881781
Cerecer-Gil, Figuera, Llamas, Lara, Escamilla, Ramos, Estrada, Hussain, Gaal, Korpershoek, de Krijger, Dinjens, Devilee, Bayley: Mutation of SDHB is a cause of hypoxia-related high-altitude paraganglioma. in Clinical cancer research : an official journal of the American Association for Cancer Research 2010
Show all 4 references for ABIN1881781
Human Polyclonal SDHB Primary Antibody for ICC, IF - ABIN4352351
Morton, Beltram, Carter, Michailidou, Gorjanc, McFadden, Barrios-Llerena, Rodriguez-Cuenca, Gibbins, Aird, Moreno-Navarrete, Munger, Svenson, Gastaldello, Ramage, Naredo, Zeyda, Wang, Howie, Saari et al.: Genetic identification of thiosulfate sulfurtransferase as an adipocyte-expressed antidiabetic target in mice selected for leanness. ... in Nature medicine 2016
Show all 2 references for ABIN4352351
Human Polyclonal SDHB Primary Antibody for ELISA, WB - ABIN185447
Selak, Armour, MacKenzie, Boulahbel, Watson, Mansfield, Pan, Simon, Thompson, Gottlieb: Succinate links TCA cycle dysfunction to oncogenesis by inhibiting HIF-alpha prolyl hydroxylase. in Cancer cell 2005
Show all 2 references for ABIN185447
Cow (Bovine) Polyclonal SDHB Primary Antibody for WB - ABIN2783181
Cascón, Landa, López-Jiménez, Díez-Hernández, Buchta, Montero-Conde, Leskelä, Leandro-García, Letón, Rodríguez-Antona, Eng, Neumann, Robledo: Molecular characterisation of a common SDHB deletion in paraganglioma patients. in Journal of medical genetics 2008
Show all 2 references for ABIN2783181
sdhB mutant is hypersensitive to oxygen and displays hallmarks of a progeroid syndrome
For classification, tumors were characterized by SDHA (show SDHA Antibodies), B, C, or D (SDHX) mutations and other genetic and epigenetic alterations, including presence of mutations in germline
Mutations in some enzymes of the TCA cycle: Isocitrate dehydrogenase (IDH (show IDH1 Antibodies)), succinate dehydrogenase (SDH (show SDHA Antibodies)) and fumarate hydratase (FH (show FH Antibodies)) are associated with the accumulation of metabolites that are able to influence many aspects of cancer development and progression and for this reason are termed onco-metabolites.
Heterozygous germline deletions of up to 104 kb in size were identified in SDHB, SDHC (show SDHC Antibodies), SDHD (show SDHD Antibodies) and flanking genes in 20 paraganglioma-pheochromocytoma patients. The exact breakpoint could be determined in 16 paraganglioma-pheochromocytoma patients of which 15 were novel deletions
compound germline heterozygosity of mouse Sdhb/Sdhc/Sdhd null alleles blunts chronic hypoxia-induced increases in hemoglobin levels, an adaptive response mainly regulated by HIF-2a
Of which 4 SDHB and 2 TMEM127 (show TMEM127 Antibodies) mutations were novel.
Data suggest that succinate dehydrogenases SDHA (show SDHA Antibodies) and SDHB immunohistochemistry should be interpreted with caution, due to possible false-positive or false-negative results, and ideally in the setting of quality assurance provided by molecular testing.
Our study, suggests that SDH (show SARDH Antibodies) loss was suggestive of metastatic behavior in addition to younger age at diagnosis, larger tumor size, and higher Ki67 (show MKI67 Antibodies) proliferation rate and catecholamine type in paragangliomas of the urinary bladder
Our results demonstrated that down-regulation of SDHB and up-regulation of PDK1 (show PDK1 Antibodies) may be novel biomarkers for predicting advanced tumor progression and unfavorable prognosis in recurrent nasopharyngeal carcinoma patients
According to international guidelines, SDHB, SDHC (show SDHC Antibodies), and SDHD (show SDHD Antibodies) genetic testing were performed in this patient, but not SDHA (show SDHA Antibodies), which would have been prescribed only after surgery, in case of SDHA (show SDHA Antibodies) negative immunohistochemistry
that SDHAF1 (show SDHAF1 Antibodies) contributes to iron-sulfur (Fe-S) cluster incorporation into the Fe-S subunit of CII, SDHB.
tissue expression analysis indicated that that swine SDHB, SNRPA (show SNRPA Antibodies) and CRYBB1 (show CRYBB1 Antibodies) gene were differentially expressed in tissues including fat, lung, muscle, small intestine, kidney, large intestine, spleen and liver
Data show that lack of succinate dehydrogenase (SDH (show SDHA Antibodies)) activity commits cells to consume extracellular pyruvate.
Using Sdhb(+/-) mice, we provide evidence that pituitary hyperplasia in SDHx-deficient cells may be the initial abnormality in the cascade of events leading to pituitary adenoma formation.
Tumor-derived FH and SDH (show SDS Antibodies) mutations accumulate fumarate and succinate, leading to enzymatic inhibition of multiple alpha-KG-dependent dioxygenases and consequent alterations of genome-wide histone and DNA methylation (show HELLS Antibodies).
Data show that two subunits of complex II (succinate dehydrogenase (show SDHD Antibodies), or SDH (show SDS Antibodies)), SDHA (show SDHA Antibodies) and SDHB, interacted specifically with SIRT3 (show SIRT3 Antibodies).
Complex II of the respiratory chain, which is specifically involved in the oxidation of succinate, carries electrons from FADH to CoQ. The complex is composed of four nuclear-encoded subunits and is localized in the mitochondrial inner membrane. The iron-sulfur subunit is highly conserved and contains three cysteine-rich clusters which may comprise the iron-sulfur centers of the enzyme. Sporadic and familial mutations in this gene result in paragangliomas and pheochromocytoma, and support a link between mitochondrial dysfunction and tumorigenesis.
succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial
, succinate dehydrogenase complex subunit B
, COMPLEX II: iron-sulfur subunit
, iron-sulfur protein subunit of succinate dehydrogenase
, succinate dehydrogenase
, succinate dehydrogenase B
, succinate dehydrogenase Iron-sulfur
, succinate dehydrogenase Iron-sulfur protein
, succinate dehydrogenase iron protein
, succinate dehydrogenase subunit b
, iron-sulfur subunit of complex II
, Iron-sulfur subunit of complex II