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SYN1 is a member of the synapsin gene family. Additionally we are shipping Synapsin I Kits (27) and Synapsin I Proteins (17) and many more products for this protein.
Showing 10 out of 304 products:
Cow (Bovine) Polyclonal SYN1 Primary Antibody for DB, WB - ABIN372719
Jovanovic, Benfenati, Siow, Sihra, Sanghera, Pelech, Greengard, Czernik: Neurotrophins stimulate phosphorylation of synapsin I by MAP kinase and regulate synapsin I-actin interactions. in Proceedings of the National Academy of Sciences of the United States of America 1996
Show all 8 references for ABIN372719
Cow (Bovine) Polyclonal SYN1 Primary Antibody for IHC (fro), WB - ABIN372718
Nayak, Moore, Browning: Ca2+/calmodulin-dependent protein kinase II phosphorylation of the presynaptic protein synapsin I is persistently increased during long-term potentiation. in Proceedings of the National Academy of Sciences of the United States of America 1997
Show all 7 references for ABIN372718
Human Monoclonal SYN1 Primary Antibody for WB - ABIN393800
Bailey, Xie, Do, Montpetit, Diaz, Mohan, Keavney, Yusuf, Gerstein, Engert, Anand: Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study. in Diabetes Care 2010
Show all 5 references for ABIN393800
Human Polyclonal SYN1 Primary Antibody for WB - ABIN372717
Kao, Song, Porton, Ming, Hoh, Abraham, Czernik, Pieribone, Poo, Greengard: A protein kinase A-dependent molecular switch in synapsins regulates neurite outgrowth. in Nature neuroscience 2002
Show all 3 references for ABIN372717
Human Polyclonal SYN1 Primary Antibody for IHC (fro), IF - ABIN372716
Feng, Chi, Blanpied, Xu, Magarinos, Ferreira, Takahashi, Kao, McEwen, Ryan, Augustine, Greengard: Regulation of neurotransmitter release by synapsin III. in The Journal of neuroscience : the official journal of the Society for Neuroscience 2002
Show all 2 references for ABIN372716
Human Polyclonal SYN1 Primary Antibody for WB - ABIN197522
Bonanomi, Menegon, Miccio, Ferrari, Corradi, Kao, Benfenati, Valtorta: Phosphorylation of synapsin I by cAMP-dependent protein kinase controls synaptic vesicle dynamics in developing neurons. in The Journal of neuroscience : the official journal of the Society for Neuroscience 2005
Show all 2 references for ABIN197522
Human Polyclonal SYN1 Primary Antibody for ICC, IF - ABIN152646
Hill, Mordes, Cameron, Neuberg, Landini, Eggan, Livingston: Two familial ALS proteins function in prevention/repair of transcription-associated DNA damage. in Proceedings of the National Academy of Sciences of the United States of America 2016
Cow (Bovine) Polyclonal SYN1 Primary Antibody for WB - ABIN372721
Bähler, Greengard: Synapsin I bundles F-actin in a phosphorylation-dependent manner. in Nature 1987
Human Polyclonal SYN1 Primary Antibody for IF, IHC - ABIN1532657
Ross, Grafham, Coffey, Scherer, McLay, Muzny, Platzer, Howell, Burrows, Bird, Frankish, Lovell, Howe, Ashurst, Fulton, Sudbrak, Wen, Jones, Hurles, Andrews, Scott, Searle, Ramser, Whittaker, Deadman et al.: The DNA sequence of the human X chromosome. ... in Nature 2005
Cerebral malaria causes pre-synaptic excitation and eventually activation of synapsin I, leading to increased neurotransmitter release.
Patterns of the immunoreactivity with antibodies to SNAP-25 (show SNAP25 Antibodies), synapsin-I and synaptophysin (show SYP Antibodies) are completely appropriate to those of adult's OB on the 38-40 weeks of the prenatal development.
The implementation of the AlphaScreen pSYN1 assay and future development of additional primary neuronal HTS (show APCDD1 Antibodies) assays provides an attractive approach for discovery of novel classes of therapeutic candidates for a variety of CNS disorders.
these findings suggest PRICKLE1 (show PRICKLE1 Antibodies) mutations contribute to ASD (show ARSD Antibodies) by disrupting the interaction with SYN1 and regulation of synaptic vesicles.
Data indicate that in patients carrying the W356x mutation the function of synapsin I is markedly impaired, and support the value of Syn1(-/-) mice as an experimental model mimicking the human pathology.
Epileptogenic Q555X SYN1 mutant triggers imbalances in release dynamics and short-term plasticity.
The histone modification marks were significantly increased in major depression and this effect was correlated with significant increases in SYN1b gene expression.
A conserved region of human and mouse SYN1 promoters contains cis (show CISH Antibodies)-sites for the transcriptional activator Sp1 (show PSG1 Antibodies) in close proximity to REST binding motifs.
The allelic frequencies of SYN1 are associated with Korean female schizophrenia.
SYN1 loss-of-function mutations in autism and partial epilepsy cause impaired synaptic function.
Synapsin I is localized and produced at mature axon terminals and at immature growth cones.
HSV-1-infected neurons also exhibite significantly reduced expression of the presynaptic proteins synapsin-1 and synaptophysin (show SYP Antibodies). These effects depended on GSK-3 (show GSK3b Antibodies) activation and intraneuronal accumulation of Ab
Functions of synapsins in corticothalamic facilitation: important roles of synapsin I
SynI mRNA and protein levels are down-regulated in the hippocampus of naive and Morris water maze-treated En2 (show EN2 Antibodies)-/- mice.
these findings suggest PRICKLE1 (show PRICKLE1 Antibodies) mutations contribute to ASD (show GUSB Antibodies) by disrupting the interaction with SYN1 and regulation of synaptic vesicles.
during chronic modification of neuronal activity and is an essential downstream effector for the Cdk5 (show CDK5 Antibodies)-mediated homeostatic scaling.
O-GlcNAcylation of Thr (show TRH Antibodies)-87 interferes with folding of the ALPS motif, providing a means for regulating the association of synapsin I with SVs (show FGFR2 Antibodies) as a mechanism contributing to synapsin I localization and RPSV generation.
This study demonstrated a seizure-inducing potential of regular handling in both Syn1KO and Syn2KO mice during a period between P21 (show D4S234E Antibodies) and 4 1/2 months of age.
These results raise the possibility that Ser (show SIGLEC1 Antibodies)(603) on synapsin I is alternatively phosphorylated by p21 (show CDKN1A Antibodies)-activated kinases, not only by CaMKII (show CAMK2G Antibodies), in neuronal cells in response to some stimulants.
Synapsin-Rab3 (show RAB3A Antibodies) interaction may participate in the regulation of synaptic vesicle trafficking within the nerve terminals.
Interacts with rab3 (show RAB3A Antibodies) protein; this interaction is likely to play a major role in the modulation of neurotransmitter release.
This study reports molecular cloning and characterization of the coding sequence of the porcine ortholog of syn (show SYNM Antibodies) I, including identification and verification at the protein level of an alanine-encoding insert.
This gene is a member of the synapsin gene family. Synapsins encode neuronal phosphoproteins which associate with the cytoplasmic surface of synaptic vesicles. Family members are characterized by common protein domains, and they are implicated in synaptogenesis and the modulation of neurotransmitter release, suggesting a potential role in several neuropsychiatric diseases. This member of the synapsin family plays a role in regulation of axonogenesis and synaptogenesis. The protein encoded serves as a substrate for several different protein kinases and phosphorylation may function in the regulation of this protein in the nerve terminal. Mutations in this gene may be associated with X-linked disorders with primary neuronal degeneration such as Rett syndrome. Alternatively spliced transcript variants encoding different isoforms have been identified.
, synapsin 1
, brain protein 4.1