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catalyzes the transfer of the terminal phosphate of ATP to thymidine to form thymidine 5'-phosphate (dTMP) [RGD, Feb 2006].. Additionally we are shipping Thymidine Kinase 1, Soluble Antibodies (74) and Thymidine Kinase 1, Soluble Kits (27) and many more products for this protein.
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Human TK1 Protein expressed in Escherichia coli (E. coli) - ABIN1098640
Chang, Huang, Chi: Serine 13 is the site of mitotic phosphorylation of human thymidine kinase. in The Journal of biological chemistry 1998
Show all 2 references for ABIN1098640
The down-regulation of Tk1 activity unmasks Tk2 deficiency in Tk2-/- mice and correlates with the onset of mtDNA depletion in the brain and the heart.
blood cells are less dependent on mitochondrial Tk2 compared with several other tissues; these cells can synthesize deoxyribonucleotides required for mtDNA replication by alternative pathways such as phosphorylation of thymidine by cytosolic Tk1
Mutations in the TK1 gene were studied in neonatal transgenic mice treated with AZT.
the small colony mutant phenotype in L5178Y lymphoma is not caused by deletion of both Trp53 (show TP53 Proteins) and thymidine kinase 1
Data show that the median thymidine kinase (TK1) levels found in sera from breast cancer patients with T1 to T4 stage disease were 0.31, 0.46, 0.47, and 0.55 ng/ml, and these levels significantly differed from healthy controls.
STK1 (show CDK7 Proteins) is a reliable biomarker for discovering people with malignant tumors in cancer screening.
Serum Thymidine Kinase 1 Activity Following Nephrectomy for Renal Cell Carcinoma (show MOK Proteins) and Radiofrequency Ablation of Metastases to Lung and Liver
TK1 expression is significantly different in invasive urothelial carcinoma and benign urothelium, which underlines its potential as a diagnostic marker
Protein expression of BIRC5 (show BIRC5 Proteins), TK1, and TOP2A (show TOP2A Proteins) in malignant peripheral nerve sheath tumours--A prognostic test after surgical resection.
High Thymidine Kinase expression is associated with adenocarcinoma in Non-small Cell Lung Cancer.
These results demonstrate that there are differences in the specific activities and the subunit compositions of STK1 (show CDK7 Proteins) in hematological malignancies compared with breast and prostate cancer.
A regression analysis showed that only TK1 levels were significant (relative risk (RR)=1.03 for each unit, confidence interval (CI)=1-1.05; p=0.015) for diagnosing a true transformation
We suggest that a chip including DPYD (show DPYD Proteins), TYMS (show TYMS Proteins), TYMP (show TYMP Proteins), TK1, and TK2 genes is a potential tool to predict response in LARC (show CCL20 Proteins) following fluoropyrimidine-based CCRT.
Nuclear TK1 expression in early grade cervical intraepithelial neoplasia predicts risk for progression to malignancy
catalyzes the transfer of the terminal phosphate of ATP to thymidine to form thymidine 5'-phosphate (dTMP)
, thymidine kinase, cytosolic
, thymidine kinase 1, soluble
, thymidine kinase 1
, Thymidine kinase, cytosolic
, thymidine kinase
, thymidine kinase 1 soluble isoform
, thymidine kinase-1