TK1 Protein (His tag)
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- Target See all TK1 Proteins
- TK1 (Thymidine Kinase 1, Soluble (TK1))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- Human Cells
- Purification tag / Conjugate
- This TK1 protein is labelled with His tag.
- Purpose
- Recombinant Human TK1 Protein (His Tag)
- Sequence
- Met 1-Asn234
- Characteristics
- Recombinant Human Thymidine kinase, Cytosolic is produced by our Mammalian expression system and the target gene encoding Met1-Asn234 is expressed with a 6His tag at the C-terminus.
- Purity
- > 90 % as determined by reducing SDS-PAGE.
- Endotoxin Level
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product TK1 Protein
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Thymidine Kinase 1, Soluble (TK1) (AA 2-242) protein (His tag)
TK1 Origin: Dog Host: Escherichia coli (E. coli) Recombinant > 95 % as determined by Tris-Bis PAGE
Thymidine Kinase 1, Soluble (TK1) (AA 2-234) protein (His tag)TK1 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % by SDS-PAGE gel analyses ELISA, WB
Thymidine Kinase 1, Soluble (TK1) (AA 1-234) protein (GST tag)TK1 Origin: Human Host: Wheat germ Recombinant ELISA, WB, AP, AA
Thymidine Kinase 1, Soluble (TK1) (AA 157-234) protein (GST tag)TK1 Origin: Human Host: Wheat germ Recombinant ELISA, WB, AP, AA
Thymidine Kinase 1, Soluble (TK1) (AA 2-234) protein (His tag)Crystallography grade TK1 Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, SDS, WB, Crys
Thymidine Kinase 1, Soluble (TK1) (AA 2-233) protein (His tag)Crystallography grade TK1 Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, SDS, WB, Crys
Thymidine Kinase 1, Soluble (TK1) (AA 1-376), (full length) protein (His tag)TK1 Origin: Herpes Simplex Virus (HSV) Host: Escherichia coli (E. coli) Recombinant > 90 % SDS
Thymidine Kinase 1, Soluble (TK1) protein (DYKDDDDK Tag)TK1 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- Restrictions
- For Research Use only
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- Format
- Frozen, Liquid
- Buffer
- Supplied as a 0.2 μm filtered solution of 20 mM TrisHCl,150 mM NaCl,1 mM DTT,2 mM EDTA, 10 % Glycerol, pH 7.5.
- Storage
- -20 °C
- Storage Comment
- Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
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- Target
- TK1 (Thymidine Kinase 1, Soluble (TK1))
- Alternative Name
- TK1 (TK1 Products)
- Synonyms
- fi19b06 Protein, zgc:55362 Protein, wu:fi19b06 Protein, TK1 Protein, tk2 Protein, D530002A18Rik Protein, Tk-1 Protein, Tk1a Protein, Tk1b Protein, TK2 Protein, Tk Protein, TK Protein, thymidine kinase 1, soluble Protein, thymidine kinase 1 Protein, thymidine kinase, cytosolic Protein, Thymidine kinase, cytosolic Protein, temporal expression: early Protein, thymidine kinase Protein, Tk thymidine kinase Protein, tk1 Protein, TK1 Protein, EDI_049980 Protein, kith Protein, J2R Protein, HVT031 Protein, Tk1 Protein, tk Protein
- Background
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Background: Thymidine kinase 1(TK1) belongs to the thymidine kinase family. It is located in the cytoplasm, and phosphorylated on Ser-13 in mitosis during post-translational modification. Two forms of this protein have been identified in animal cells, one in cytosol TK1 and one in mitochondria TK2. Thymidine kinases have a key function in the synthesis of DNA and thereby in cell division, as they are part of the unique reaction chain to introduce deoxythymidine into the DNA. Activity of the cytosolic enzyme is high in proliferating cells and peaks during the S-phase of the cell cycle, while it is very low in resting cells. TK1 acts as a homotetramer, and can transform thymidime to thymidine 5'-phosphate with the help of ATP
Synonym: Thymidine kinase, cytosolic,TK1
- Molecular Weight
- 26.5 kDa
- UniProt
- P04183
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