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Sequence-specific DNA-binding protein that interacts with inducible viral and cellular enhancer elements to regulate transcription of selected genes. Additionally we are shipping TFAP2E Proteins (4) and many more products for this protein.
Showing 9 out of 10 products:
Cow (Bovine) Polyclonal TFAP2E Primary Antibody for WB - ABIN2779389
Tummala, Romano, Fuchs, Sinha: Molecular cloning and characterization of AP-2 epsilon, a fifth member of the AP-2 family. in Gene 2003
These findings reveal that Tfap2 (show TFAP2A Antibodies) activity, mediated redundantly by Tfap2a (show TFAP2A Antibodies) and Tfap2e, promotes melanophore differentiation in parallel with Mitf (show MITF Antibodies) by an effector other than Kit.
Hypermethylation of TFAP2E was associated with lack of response to fluorouracil-based chemotherapy, indicating that it might be a potential predictor of treatment response in patients with gastric cancer.
AP-2E was frequently hypermethylated in tumors from patients with colorectal cancer
AP-2epsilon indirectly interacts with the core promoter of COL2A1 (show COL2A1 Antibodies) and subsequently inhibits its transcriptional activity, thus modulating cartilage development.
TFAP2E hypermethylation is associated with clinical nonresponsiveness to chemotherapy in colorectal cancer.
Report of the expression and function of Tfap2e in developing Xenopus laevis; propose that Tfap2e is a novel player in the gene regulatory network controlling neural crest specification in Xenopus downstream of Pax3 (show PAX3 Antibodies) and Zic1 (show ZIC5 Antibodies)
We reveal a novel role of AP-2epsilon in the regulation of gene expression in articular chondrocytes, as well as in osteoarthritis development, through modulation of Mmp13 (show MMP13 Antibodies) expression and activity.
cloning and characterization; AP-2 epsilon is expressed most prominently in the mitral cell layer of the developing olfactory bulb; it is able to activate transcription in a binding site-dependent manner
AP-2 epsilon is important for the development of the olfactory system.
Sequence-specific DNA-binding protein that interacts with inducible viral and cellular enhancer elements to regulate transcription of selected genes. AP-2 factors bind to the consensus sequence 5'-GCCNNNGGC-3' and activate genes involved in a large spectrum of important biological functions (By similarity).
, transcription factor AP-2-epsilon
, activating enhancer-binding protein 2-epsilon
, adaptor-related protein complex 2, epsilon subunit
, activating enhancer-binding protein 2 epsilon