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Translocase of Inner Mitochondrial Membrane 8 Homolog A (Yeast) Proteins (TIMM8A)

This translocase is involved in the import and insertion of hydrophobic membrane proteins from the cytoplasm into the mitochondrial inner membrane. Additionally we are shipping Translocase of Inner Mitochondrial Membrane 8 Homolog A (Yeast) Antibodies (31) and Translocase of Inner Mitochondrial Membrane 8 Homolog A (Yeast) Kits (19) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
TIMM8A 1678 O60220
TIMM8A 84383 Q9WVA1
Mouse TIMM8A TIMM8A 30058 Q9WVA2
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Top Translocase of Inner Mitochondrial Membrane 8 Homolog A (Yeast) Proteins at antibodies-online.com

Showing 8 out of 9 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
Yeast Zebrafish His tag   1 mg Log in to see 56 to 66 Days
$2,143.17
Details
Yeast Takifugu rubripes His tag   1 mg Log in to see 56 to 66 Days
$2,143.17
Details
Yeast Rat His tag   1 mg Log in to see 56 to 66 Days
$2,165.17
Details
Yeast Cow His tag   1 mg Log in to see 56 to 66 Days
$2,165.17
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   100 μg Log in to see 3 to 4 Days
$388.93
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

TIMM8A Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
,
Rat (Rattus)

More Proteins for Translocase of Inner Mitochondrial Membrane 8 Homolog A (Yeast) (TIMM8A) Interaction Partners

Human Translocase of Inner Mitochondrial Membrane 8 Homolog A (Yeast) (TIMM8A) interaction partners

  1. The results of this study demonistrated that the syndrome of deafness-dystonia is cause by mutation of Timm8a.

  2. knockdown of the TIMM8A gene by RNA interference did not show an influence on the oxygen respiration rate and the mitochondrial membrane potentia

  3. Interaction of TIMM8a with the signal transduction adaptor molecule STAM1 (show STAM Proteins).

  4. Intronic mutations in the DDP1 gene can also cause X-linked dystonia-deafness syndrome.

  5. Bax (show BAX Proteins)/Bak (show BAK1 Proteins)-dependent release of DDP/TIMM8a promotes Drp1 (show CRMP1 Proteins)-mediated mitochondrial fission and mitoptosis during programmed cell death.

  6. Mutation in TIMM8a is associated with deafness-dystonia (Mohr-Tranebjaerg) syndrome

  7. A sporadic 42-year-old man with MTS presenting with postlingual deafness, adult-onset progressive dystonia with marked arm tremor, mild spasticity of the legs, and visual disturbance due to a novel mutation in the DDP1 gene.

  8. mRNA expression demonstrate increased TIMM8A mRNA levels in cultured fibroblasts from a patient with Mohr-Tranebjaerg Syndrome.

Mouse (Murine) Translocase of Inner Mitochondrial Membrane 8 Homolog A (Yeast) (TIMM8A) interaction partners

Translocase of Inner Mitochondrial Membrane 8 Homolog A (Yeast) (TIMM8A) Protein Profile

Protein Summary

This translocase is involved in the import and insertion of hydrophobic membrane proteins from the cytoplasm into the mitochondrial inner membrane. The gene is mutated in Mohr-Tranebjaerg syndrome/Deafness Dystonia Syndrome (MTS/DDS) and it is postulated that MTS/DDS is a mitochondrial disease caused by a defective mitochondrial protein import system. Defects in this gene also cause Jensen syndrome\; an X-linked disease with opticoacoustic nerve atrophy and muscle weakness. This protein, along with TIMM13, forms a 70 kDa heterohexamer. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

Gene names and symbols associated with TIMM8A

  • translocase of inner mitochondrial membrane 8 homolog A (yeast) (TIMM8A)
  • mitochondrial import inner membrane translocase subunit Tim8 A-like (LOC101061507)
  • translocase of inner mitochondrial membrane 8 homolog A (yeast) (timm8a)
  • translocase of inner mitochondrial membrane 8 homolog a1 (yeast) (Timm8a1)
  • translocase of inner mitochondrial membrane 8A1 (Timm8a1)
  • DDP protein
  • Ddp1 protein
  • DFN1 protein
  • DXHXS1274E protein
  • Fci-12 protein
  • im:6896085 protein
  • MTS protein
  • TIM8 protein
  • Tim8a protein
  • Timm8a protein
  • zgc:100916 protein

Protein level used designations for TIMM8A

translocase of inner mitochondrial membrane 8 homolog A (yeast) , mitochondrial import inner membrane translocase subunit Tim8 A , Mitochondrial import inner membrane translocase subunit Tim8 A , deafness dystonia protein , X-linked deafness dystonia protein , deafness dystonia protein 1 , deafness/dystonia peptide , deafness dystonia protein 1 homolog , translocase of inner mitochondrial membrane 8 homolog a , translocase of inner mitochondrial membrane 8 homolog a1

GENE ID SPECIES
422190 Gallus gallus
480986 Canis lupus familiaris
702885 Macaca mulatta
738690 Pan troglodytes
101061507 Takifugu rubripes
1678 Homo sapiens
515109 Bos taurus
445243 Danio rerio
101105475 Ovis aries
84383 Rattus norvegicus
30058 Mus musculus
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